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A question on oral freebase DMT

C

Chocolate-Salad

Bluelighter
Joined
Jun 8, 2012
Messages
71
I believe this falls within the rules of PD and is in the spirit of harm reduction.

I know there's threads on this, but there's a problem with each of them.

I've read reports of users suggesting to take upwards of 100-200mg* of mao-inhibited dmt while others claim 75mg can be intense*.

I also found a poll* that yielded inconsistent results.

An online user posted an estimation scale
.45-.46 mg/kg : light dosage/sensitive*
.47-.485 mg/kg : moderate dosage/average
.49-.51 mg/kg : strong dosage/resistant
Click to expand...

Random doses calculated using this scale appear lower than plenty of reported doses.

I just whipped up a simple html calculator from a few things might be useful in more places than just this thread. The use of it isn't required, but it would help to get a more accurate scale going for each level!



So, where I'm getting at is that I'd like to see if people could contribute their findings to the community to help others find a comfortable and accurate dose. Hopefully a compilation of data will lead to a better understand of how one should dose.
This is a call to those with experience! What are your low/mid/high doses?
 
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It isn't at all confirmed that dosage is a function of body weight. It is with things like alcohol where the drug disperses over the bodily fluids and tissues, but as far as I know with most psychedelics it isn't the deciding factor, it may be that something like serotonin receptor population density is the most important factor (maybe there is much more variance in serotonin receptor densities than GABAr densities? I honestly don't know).

You cannot quickly check that like knowing your body weight and it would require titration and would account for the unexplained inconsistencies.
 
So it's based more on brain chemistry? The dosage range people experience intense effects from seems to vary from 75 to 200 mg. I'm not really well versed on the chemistry of the brain but seeing as how there can be a huge difference in dose, I would think there'd be a huge difference in brain chemistry as well. Am I mistaken?

/edit
But then why is dmt the only tryptamine that has such a large dose difference in what people classify as 'heavy' oral doses?
 
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DPT has HUGE variances in doses.
Some people need 30mg insufflated, I've personally done over 100mg and not gotten where I need to go.
This isn't unheard of with DPT but I still think I have bunk product
 
I would think since DPT freebase is an oil that it would inherently be more difficult to work with no? Is it possibly because of impurities from synthesis/and or cut product that makes the freebase easier to dose since it's essentially pure after freebasing? Sorry, I don't mean to be an ass I was just genuinely curious about that remark and I'm about to do several experiments with DPT for essentially the first time (besides a test just to see how much it sucks to snort -and I found it very grim to put up my nose).
 
More or less I was commenting on the issues with method. Since I don't insufflate I can't comment about that, but DPT seems to metabolize very strangely with oral ROA, so to get more predictable effects I find to vaporize the freebase more efficient. Your mileage might vary though, as it really does tend to do with DPT. If you have a little HCL to spare I'd recommend you convert some with NaOH and see what works best yourself.
 
Well, back to topic.. what would help me determine where to start with oral DMT? I don't want to end up in mental ward hyperspace, just regular hyperspace. It's impossible to guesstimate my dosage with everyone's subjective opinions and I wouldn't exactly want to waste material on an underwhelming dose.
 
Well start low.
try maybe 30mg and see where it gets you, have more ready in case you want to take more
The maoi should be active long enough for you to add on top of your dose
 
I don't consume psychedelics normally unless I feel like the time is right. I don't do it often. I feel like there needs to be a 'perfect storm', not just spontaneity if you know what I mean. That being said, I feel like I'm hard headed when it comes to psychedelics and I'd need to start somewhere higher, like say 50-60mg. And that's what I hope a powerful experience would be. 200mg down the hatch sounds downright terrifying.

Is caapi or harmalas preferred? People say that caapi is more than just an maoi and has character and suggest using it over harmala teas. Is this true? Does anybody prefer one to the other?
 
Chocolate-Salad said:
.

Is caapi or harmalas preferred? People say that caapi is more than just an maoi and has character and suggest using it over harmala teas. Is this true? Does anybody prefer one to the other?
Click to expand...

Caapi also contains harmalas (which include harmine, harmaline, tetrahydroharmine, ect) , and yes, I have heard that it is preferred over Syrian Rue.
I have not yet met the character of the ayahuasca vine, as I havnt tried the kilo I acquired a couple months ago.
Waiting for the perfect time.
I have done much research on the adequate dosage for MAOI enhanced dmt, and I have found that it varies greatly.
I think that has a lot to do with personal preference of effects, along with individual differences in physiology.

I personally am a fan of low dose dmt, so I am going to start with numbers like 50g caapi , 30mg dmt, and build to numbers like 150g + caapi , 200g + dmt, varying between heavy harmalas and heavy dmt

Always prep a redose, as you never know when you will want to kick it to the next level.
 
Chocolate-Salad said:
So it's based more on brain chemistry? The dosage range people experience intense effects from seems to vary from 75 to 200 mg. I'm not really well versed on the chemistry of the brain but seeing as how there can be a huge difference in dose, I would think there'd be a huge difference in brain chemistry as well. Am I mistaken?
Click to expand...

I think that's right.

Big differences in brain chemistry like that (i.e. significant variance in receptor populations) may seem bizarre because you'd think we are supposed to function using a nervous system with a delicate balance, right?
1) Well first of all: people can indeed be pretty different in personality and congenital traits profile, but I think that has much more to do with the unique way each brain develops - on a larger level than chemistry, rather anatomical and topological. (Edit: though I can imagine congenitally determined receptor populations of some kinds being low leading to things like dysthemia, limited inhibition or high excitability - and things like dysthemia seem to be genetically passed on pretty often). A part of this would be genetically driven and preset, but the unique set of experiences each human life comprises and the path emotions and cognitions develop and learn from events also determines a pretty big amount. To get an idea of the influence we need to look at identical twins, especially when raised in different environments - but even when raised together: again each experience and total set of those experiences, thus each life... is unique if only because every location is unique.
2) There are a lot of examples like developing drug tolerance and significant downregulation of receptor densities meaning that they can apparently become more scarce with the same rate of significance as the significance of the variance I initially mentioned in this post. However from what I know about consciousness emergent from our CNS I'd say that it continuously strives to reach coherence and there are probably a lot of equilibria that support this. Meaning that if there are changes and influences the brain finds a way to recalibrate and orchestrate each specialized circuit to join in a coherent field by any means necessary. The result would usually be called our baseline. Though that term is elusive because homeostasis is never absolutely complete. But it can be significantly stabilized.

Note: I am not a neurologist or anything like that and I theorize so please correct me where I am wrong, but I feel at least confident to say that brain chemistry can be pretty different and this is continously demonstrated by how different people can react to medication and recreational drugs, and that goes beyond psychological explanations.
 
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I've always preferred moclobemide as the MAOI. It's hard to recomend a dose, oral DMT is probably the perfect psychedelic (apart from the initial nausea). It has the greatest bodyhigh of any drug and it's the most psychedelic. It also has the biggest "presence" of any drug I've ever taken. The feeling that it's an ancient spirit/part of you reconnecting with yourself or "coming home".

For dosage it's always start low and see how you go. I'd recomend at least a full 00 capsule - if you're experienced with psychedelics a capsule and a half or two.
 
Solipsis, I always love reading your posts. You're a fountain of knowledge.
I've heard that of moclobemide, but it isn't exactly readily available. Dosing rue seems easiest and I may take that route whenever the chance arises.
 
Chocolate-Salad said:
Solipsis, I always love reading your posts. You're a fountain of knowledge.
I've heard that of moclobemide, but it isn't exactly readily available. Dosing rue seems easiest and I may take that route whenever the chance arises.
Click to expand...

Trade name of moclobemide is "aurorix". It actually works out cheaper than syrian rue.
 
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