20mg of APVP is a fairly strong dose and a decent sized oral dose, 40mg is just absolutely ridiculous and I personally don't see why anyone would go that high unless they had a strong tolerance. My girlfriend actually suggested that we try this combo once and I never shot down any idea quicker before in my life. Now I'm not one of those people who thinks you should only use psychedelics for spiritual purposes, if you want to trip recreationally I say go for it, a good majority of my trips are for recreational purposes. When she brought it up I quickly shot it down and told her that mixing 5-Meo-Mipt with A-PVP is a slap in Moxys face. Don't get it twisted, I have nothing against A-PVP either, but it is not one to mix with psychedelics, especially a 5-MeO tryptamine. A-PVP feels very hard on the body (personally at least) and that mixed with the high blood pressure and increased heart rate of 5-Meo-Mipt is a train wreck waiting to happen IMO.
What I get from a-PVP is labored breathing, heart stress and sweat pouring out my underarms. I had to stick paper towel under each arm to absorb it. I was also thirsty as a muhfukker and could hardly eat anything. The euphoria was minor. My nutsack was also contracted into a hard flat configuration and I had a case of noodle-pud. What little euphoria I got was nowhere near worth the side effects, but maybe some people like sweat pouring out their underarms and messed up genitalia.
This is very similar to what A-PVP would do to me. My preferred ROA was insufflated, but changing ROA's didn't really lessen the side effects, except for freebasing ( I highly recommend staying far away from this ROA with A-PVP, it's a fast track to addiction or at least a nice 24 hour binge that stopped being fun 23 hours ago). Anyways this is pretty much what APVP would do for me:
Snort my bump and about a minute get hit with strong euphoria. Seriously some of the strongest euphoria that I have personally felt, and it had the best music enhancement out of any stimulant I have ever done, short of MDMA and 4-Fluoroamphetamine. The euphoria would last anywhere from 15-45 minutes, after which I was hit by breathing becoming more difficult, heart rate through the roof, terrible heart palpitations, extreme sweating (especially the underarms), anxiety, suppressed appetite (but nowhere near as bad as any given amphetamine), terrible dry mouth (which led to very frequent urination and even further difficulty eating) and a very strong urge to re-dose. With each consecutive bump the euphoria gets less and less (for me it almost completely goes away after maybe 4 bumps) and the side effects get worse and worse, To the point of extreme anxiety about your physical well-being. It was wonderful for doing the dirty though
TL;DR - Dont mix A-PVP with any psychedelic, especially one like A-PVP. I see no pros with this combination or combining A-PVP with any other psychedelic.