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Kratom 7-OH-Mitragynine and Mitragynine Pseudoindoxyl

My suggestion for anyone using these things is to take frequent tolerance breaks if you are dependent on opioids.

My kratom use had escalated pretty wildly the past 6 months or something once I started walking again, and I started buying the 7ohm tablets from the store because regular powder just wasnt cutting it anymore. Dang they were great at first, had not gotten good nods like that outside of heroin in a long time.

Then I went ahead and grabbed a couple grams of 7ohm and pseudo extracts, and yeah it didnt take long before they were both "nothing special" really, which ultimately led me to just getting a couple grams of heroin because I really just needed anything to make my days bearable.

So over the past few weeks I tried to limit my opioid use to just a couple doses of regular kratom a day, and yeah its been ok, but Monday and Tuesday were both some tough ass days for work and for pain, and I broke down and got 3 of those 7ohm tablets from the store Monday, even if I took all three, it did not really have much effect.

I mean at this point my opioid tolerance has just been thoroughly broken over 15 years or whatever, but I'm pretty damn bummed that this stuff doesn't even really cut it anymore. I'll have to just continue my tolerance break for a bit longer and try again.
 
Man... these two drugs are EXPLODING in popularity at an alarming rate. A few months ago my vendor used to get a batch and it would take several weeks to sell out. Now they sell out in just a few days. It's actually concerning me for the future of kratom.

There are now a few subreddits dedicated to them, and those are also way more active now.

I think what's happening is everyone who tried regular kratom in the past and wasn't very impressed with it are now catching on that these are like real drugs and can nod you the fuck out.

On top of that, they are all in every vape shop now, and you have asshole companies literally labeling them as percs... I am surprised the DEA hasn't made a statement yet.
 
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Man... these two drugs are EXPLODING in popularity at an alarming rate. A few months ago my vendor used to get a batch and it would take several weeks to sell out. Now they sell out in just a few days. It's actually concerning me for the future of kratom.

There are now a few subreddits dedicated to them, and those are also way more active now.

I think what's happening is everyone who tried regular kratom in the past and wasn't very impressed with it are now catching on that these are like real drugs and can nod you the fuck out.

On top of that, they are all in every vape shop now, and you have asshole companies literally labeling them as percs... I am surprised the DEA hasn't made a statement yet.
They sell perks in one of the smoke shops by me. They have an advertisement sign (the company) saying things like ‘fast acting!’, ‘good pain relief!’ and I kid you not … ‘not fentanyl!’
 
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Smoke shop near me sells almost all the main 7OH and pseudo tabs and shots, as well as tianeptine and the amyl replacement whose name is escaping me.

I used to be very active on the boards, specifically about kratom and other opioid use. I was heavily dependent on kratom for about a decade, most of it was at 100+gps and OPMS (when it was king). I have a long history of opioid use and was also using pharmaceutical morphine and hydrocodone regularly. I started 16mg suboxone 3 years ago to stop kratom use after everything else had failed.

Now, I find myself free to experiment and having terrible dental issues from the subs. I’ve recently started using pseudo alongside my suboxone at night and have cut my suboxone dose by 1/3. I find it rather interesting that pseudoindoxyl works alongside lower dose suboxone than heavier opiates ime.

Some may view this as backsliding. Maybe it is. But I need to try something different.
Wow yea that is interesting about the pseudo and suboxone. I like the pseudo/7oh mix but only pseudo from certain vendors (I don’t know what makes some of them different). There’s this one vendor I order pseudo from online that feels like a straight pain pill like a Roxy or something when I mix with 7oh. I only order that once in a blue moon because that shit jacks up my tolerance I believe … or either way when I did it for a while and stopped, I got a mean withdrawal. I used to take and rotate tramadol, heavy amounts of hydromorphone and then when I ran out of those .. 7oh and pseudo. I haven’t taken hydromorphone in months (which is crazy for me because I was doing it for years). But still take tramadol for chronic pain and when I run out the 7oh. Some reason though 7oh and pseudo jacks up my tramadol tolerance. So still tryin to figure shit out. It’s still really noticeable for me that I’m no longer taking hydromorphone. Anyways I’m rambling, but I feel you when you’re talking about trying something different and being unsure.

Man it really bothers me that suboxone is messing peoples teeth up. It’s so not fair to the person that’s trying to get their life together and then to encounter this problem. I feel it’s been documented long enough that they need to do something about it. I hope that you’re doing okay though. I definitely remember seeing you around and also I like your avatar lol.
Hugs 💜
 
Wow yea that is interesting about the pseudo and suboxone. I like the pseudo/7oh mix but only pseudo from certain vendors (I don’t know what makes some of them different). There’s this one vendor I order pseudo from online that feels like a straight pain pill like a Roxy or something when I mix with 7oh. I only order that once in a blue moon because that shit jacks up my tolerance I believe … or either way when I did it for a while and stopped, I got a mean withdrawal. I used to take and rotate tramadol, heavy amounts of hydromorphone and then when I ran out of those .. 7oh and pseudo. I haven’t taken hydromorphone in months (which is crazy for me because I was doing it for years). But still take tramadol for chronic pain and when I run out the 7oh. Some reason though 7oh and pseudo jacks up my tramadol tolerance. So still tryin to figure shit out. It’s still really noticeable for me that I’m no longer taking hydromorphone. Anyways I’m rambling, but I feel you when you’re talking about trying something different and being unsure.

Man it really bothers me that suboxone is messing peoples teeth up. It’s so not fair to the person that’s trying to get their life together and then to encounter this problem. I feel it’s been documented long enough that they need to do something about it. I hope that you’re doing okay though. I definitely remember seeing you around and also I like your avatar lol.
Hugs 💜

For whatever reason I don't get the same enjoyment out of pseudo as I do from 7-OH. Perhaps that's because I don't have chronic pain and don't need a painkiller. For me, the pseudo just makes me tired and feel flat, no stimulation or euphoria. And the rebound/withdrawal is nasty, aches in the joints etc, depression.

7-OH is some pretty addictive shit though. In 2024 I probably spent over $10k on it. One of my new years resolutions is to not use it. So far, that resolution hasn't been going so well 🥲
 
Wanted to chime in here (as I have been on a handful of other threads) about my recent antics with carisoprodol, as I've been spending a lot of time experimenting with mixes of kratom leaf, 7-OH, pseudo, and carisoprodol together. Most 7Heads will tell you that taking some straight kratom leaf alongside 7-OH will make the 7-OH last much longer, as will pseudo. 7-OH on its own lasts 3-4 hours for me, with kratom leaf OR pseudo it's 7-8, but with both kratom leaf AND pseudo, I'm getting easily 10-12 hours out of a single dose. I don't take it often and take frequent tolerance breaks by the way.

Carisoprodol can add at least a few more hours of duration, and DRAMATICALLY intensifies the potency of any of these mixes. My boyfriend and I have been recently referring to the combo of these four aforementioned drugs (sometimes without pseudo though) as the "maxrelax", as it's an unbelievably relaxing combination compared to other opioids/opioid combinations we've tried. It often necessitates a caffeine pill though to remain awake throughout the course of the high. I do fear that the initial overdose deaths related to 7-OH/pseudo may come from carisoprodol combinations, but the magic of 7-OH is truly unlocked via the ensemble effect with other kratom alks/kratom-derived alks like pseudo and some straight leaf, and then the magic REALLY begins to shine once the carisoprodol is introduced in my opinion. Gabapentin, baflofen, floribut, and phenibut don't hold a candle to carisoprodol as far as what it can do for buffing up the potency of opioids, it seems. Anybody doing this should cut their normal doses of opioid in half, and preload the carisoprodol ~45 minutes before taking the opioids in my opinion.
 
. I like the pseudo/7oh mix but only pseudo from certain vendors (I don’t know what makes some of them different
My guess is because very few people/labs are doing the chromatography to purify their post reaction products or even mitragynine which is their input to the 7-OH. If there are other alkaloids, they will likely follow similar reactions. I know this occurs to some extent because one of my extracts had like 95% Mitragynine, 1.6% corynantheidine, and when I converted it to 7-OH all the Mit and Cory were gone, and I was left with 50% of 7-OH and .8% of something mitraphylline. So when people are using extracts that have more alkaloids than mitragynine to make 7-OH they're getting an end product that is chemical soup. Even if youre starting with pure mitragynine the unknowns in the crude 7-OH are potentially 3 different mitragynine dimers (2 mitragynine molecules bonded to each other) plz sci hub this paper to see similar structures.) Sadly the "chemists" who are doing this process don't even know that. They don't even care.


Or if you didn't want to read the whole paper i think this link will just show the images.

On top of that, very few people are purifyng their 7-OH before oxidizing to the pseudoindoxyl (or oxoindole), so it's going to have even more unknowns. The purifications at each stage become more difficult and yield less, so the cost goes up big time. In a market that is as competitive as kratom where cost is kind of everything, you KNOW that not everyone is doing the proper cleanup. Another reason I KNOW this is happening is because I got a series of transdermal patches of MIT, of 7-OH, and Pseudo along with hundreds of the R, G, W pressies that were going around. The transdermal patches were gold, red, and then black. Pure Migraine is actually white. Pure 7-OH is a pale green. I know because of made them. Haven't made the pseudo yet.

I hate shitty chemists and kratoms businesses.
 
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Ok, I just read/reread all 3 pages and my post too.
Oh if only my tolerance hadn't shot up to these Kratom alkaloids, I'd not be spending so much $$, but I'm not as disciplined as I'd like to be, or tolerant of pain.
I'll say at $1/mg street price for real Rx oxy immediate release, Kratom alkaloid tablets run around $5 each so they cost less and beat oxy in effectiveness by a long shot. My body laughed at oxy 20mg IR after my 1st month using Kratom alkaloids.
With over 10 years in pain management, I required no less than 150 mg oxy IR /24 hours or somethings didn't get done because of pain and the mental anguish it brings.
The 100mg MS ER at 1 every 12hrs (2 a day) helps keep the base level pain from being unbearable and withdrawals away, but the oxy IR is the only way I could get going first thing in the morning when my pain is usually the worst.
I find the 100% pseudoindoxyl tablets are still the best for pain relief and not feeling wired/hyped on caffeine. Often I get the 50/50
7-OH/pseudoindoxyl tabs because 100% pseudoindoxyl is often not available locally.
I stopped using the MOJO7OHMS product because I got about 18 good, fresh, shiny tabs (3 per card) instead of the dull, crumbly ones I'd been used to and they gave me chest pain and I felt overcaffienated and it didn't help as much for pain.
I found the lavender 7-OHMS 30mg straight 7-OH tabs worked well for pain, and taking 2 helped get me moving too, like oxy has.

Well now I have gone through as much as 15 of the 7-OH 30mg tabs in 24 hours, PLUS 4 of the 20mg pseudoindoxyl/7-OH mixed or 15mg straight pseudoindoxyl tabs. That costs about $110 for the 15+4 combo, so less $$ than the bare minimum 150mg of oxy IR/24 hrs but it's still $110 a day and I can't keep that up.
Regular Kratom? Not effective without eating 40 capsules a day and burps smelling and tasting like I ate my yard, and the results being no withdrawals but hardly any pain relief.
So if anyone can advise me how to obtain pseudoindoxyl at the best price or maybe look at making it myself I'm open to a private message. I'd also like to know what has been the most effective for pain but with no hyped up side effects.
 
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Well now I have gone through as much as 15 of the 7-OH 30mg tabs in 24 hours, PLUS 4 of the 20mg pseudoindoxyl/7-OH mixed or 15mg straight pseudoindoxyl tabs.
Yeah, 7-OH and pseudo have a hard tolerance cap just like regular mit/kratom. It takes a lot longer to reach, but it exists. My tolerance has been to the point where 200mg+ of pure 7-OH powder in a single dose barely produced any effect at all other than avoiding withdrawal.

Tolerance break is required at that point.

That costs about $110 for the 15+4 combo, so less $$ than the bare minimum 150mg of oxy IR/24 hrs but it's still $110 a day and I can't keep that up.

They sell 7-OH powders now that are much much cheaper per dose compared to those pills man. I hope you aren't buying them in a headshop and paying those prices. You can get 1g of 7-OH powder for ~$80-90 after shipping (they're usually 70-85% pure). That works out to be much, much cheaper on your wallet per dose man... but also just feeds your addiction. Super easy to start taking more than you intend to when you have a scoop and a pile of powder....

Yeah once you're addicted to 7-OH and/or pseudo, regular kratom powder won't do anything at all for you. Sad. Only high doses of pure mit will have an effect. Your only option is to go on suboxone, or use high dose mitragynine extracts to taper.

So if anyone can advise me how to obtain pseudoindoxyl at the best price or maybe look at making it myself I'm open to a private message. I'd also like to know what has been the most effective for pain but with no hyped up side effects.
There is only one brand called Hydroxie that puts out REAL pseudo, but they suck and their pills have leftover solvent and have massive dose consistency issues... and overpriced.... but it's real pseudo. Also gave me liver pain/rash, probably from the solvent as I have used pseudo in the past over a year ago without that issue.

Too many companies say they have pseudo in their pills but they don't.

GC/MS cannot accurately identify mit derived alkaloids at the moment.
 
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There is only one brand called Hydroxie that puts out REAL pseudo
What a coincidence! THAT is exactly what my first experience was with concentrated Kratom alkaloids (as a broadly described category) and it really saved my trip to Hawaii. I was out of Rx, and I had 2½ days left including physically active vacation stuff, and I would have been in deep shit if not for the guy at a local shop recommending it.
Thanks for the other info, I will see what I can find.
 
Man, I'm someone who is only sporadically dependent on plain leaf and sometimes OPMS and extracts (I need to stop OPMS at the moment for a while IMO) and I've never even tried them but 7-OH and pseudo seem SUPER addictive. Would you guys who have used them generally recommend I NOT EVER get into them? Cause that's what I'm thinking. I already have an addictive personality with regular Kratom, but these seem basically like the same level or even stronger than certain street opioids. I think I'd go straight down the tubes and become a complete and utter fiend with no joy in my life other than this shit. Like, I still believe all drugs should be legal, but getting into these sounds like a good way to lose enjoyment in just about everything else in life.
 
7-OH and pseudo seem SUPER addictive. Would you guys who have used them generally recommend I NOT EVER get into them?
They are indeed very addictive, on par with other traditional opioids. Much more addictive than regular kratom or even mit extracts.

Particularly pseudoindoxyl, for whatever reason, is insidiously addictive. The withdrawals hit so fast and furious after just a few days, it's unreal and unlike any other opioid.

I have been addicted to them on and off over the last 18 months or so. It's hell, like any other drug addiction.

Plus, to state the obvious, it ruins your tolerance to regular kratom.

They also come with the gamut of issues when taking daily opioids. They gave me wicked constipation. They can mess with your sleep. They make you feel nausea, etc, etc... all much more than regular kratom.

I would stick to kratom. It's not worth it. I would ONLY ever recommend these to people who have legitimate pain management needs.
 
Man, I'm someone who is only sporadically dependent on plain leaf and sometimes OPMS and extracts
Sporadically dependent...
I wish I was at that level, but in my case it's about pain management. I'm not going to deny I've had pleasant what I'd call "side effects" like motivation to move about getting stuff done, a euphoric effect, but when debilitating pain is an obstacle and it's removed, that alone is a reason to be happy.
I also have work responsibilities and it's a physically active job.
Would you guys who have used them generally recommend I NOT EVER get into them? Cause that's what I'm thinking. I already have an addictive personality with regular Kratom, but these seem basically like the same level or even stronger than certain street opioids.
You're thinking correctly, and they are very strong.
I don't take them for "fun", it's for pain management so I can function on a reasonable level.
getting into these sounds like a good way to lose enjoyment in just about everything else in life.
Try hurting so badly that it's hard to be with yourself because of the physical pain you experience.
THAT takes the enjoyment out of life.
 
Sporadically dependent...
I wish I was at that level, but in my case it's about pain management. I'm not going to deny I've had pleasant what I'd call "side effects" like motivation to move about getting stuff done, a euphoric effect, but when debilitating pain is an obstacle and it's removed, that alone is a reason to be happy.
I also have work responsibilities and it's a physically active job.

You're thinking correctly, and they are very strong.
I don't take them for "fun", it's for pain management so I can function on a reasonable level.

Try hurting so badly that it's hard to be with yourself because of the physical pain you experience.
THAT takes the enjoyment out of life.
Man, I'm really sorry about your chronic pain. I HOPE that I don't end up that way, but truth is I'm probably headed in a relatively painful direction as well, only I don't know how bad.

I've got cervical disk disease from years of doing Brazilian Jiu-Jitsu and martial arts' training. Now, C.D.D (also called degenerative disk disease) is something that everyone ends up with anyway due to wear and tear on the neck, so it's not a good descriptor, but having it at 45 is very early onset, and I've been told that MRIs of my neck look like an 80 year old's. I've only just had my 2nd flareup in 8 years since I was diagnosed, which my physical therapist says is pretty good, but the pain was spreading from my neck to my left arm and pectoral muscle and making it hard to sleep or do much till I took a week of Naproxen. Then again, I do a lot of physical therapy to keep my neck strong which helps prevent flareups. I've also torn my ACLs three times and will someday have arthritis cause of that, but now they are ok.

I had to stop training due to my recent neck flareup and I'm just trying to get back again. If there's ever a day I can't do BJJ that will be BEYOND depressing cause it's pretty much my favorite thing in life, but I'm determined to NEVER let that happen. I'll get surgery before I stop training because I like martial arts better than drugs.

I was really just talking about the kind of anhedonia that chronic opioid use can cause because I'd heard people, either in this thread or another, say that they can no longer enjoy anything other than drugs because of their opioid use and what it's done to their brain. I wasn't in any way trying to suggest that anhedonia is worse than chronic pain, though I don't necessarily think that's what you thought I was saying...
 
Man, I'm really sorry about your chronic pain. I HOPE that I don't end up that way, but truth is I'm probably headed in a relatively painful direction as well, only I don't know how bad.

I've got cervical disk disease from years of doing Brazilian Jiu-Jitsu and martial arts' training. Now, C.D.D (also called degenerative disk disease) is something that everyone ends up with anyway due to wear and tear on the neck, so it's not a good descriptor, but having it at 45 is very early onset, and I've been told that MRIs of my neck look like an 80 year old's. I've only just had my 2nd flareup in 8 years since I was diagnosed, which my physical therapist says is pretty good, but the pain was spreading from my neck to my left arm and pectoral muscle and making it hard to sleep or do much till I took a week of Naproxen. Then again, I do a lot of physical therapy to keep my neck strong which helps prevent flareups. I've also torn my ACLs three times and will someday have arthritis cause of that, but now they are ok.

I had to stop training due to my recent neck flareup and I'm just trying to get back again. If there's ever a day I can't do BJJ that will be BEYOND depressing cause it's pretty much my favorite thing in life, but I'm determined to NEVER let that happen. I'll get surgery before I stop training because I like martial arts better than drugs.

I was really just talking about the kind of anhedonia that chronic opioid use can cause because I'd heard people, either in this thread or another, say that they can no longer enjoy anything other than drugs because of their opioid use and what it's done to their brain. I wasn't in any way trying to suggest that anhedonia is worse than chronic pain, though I don't necessarily think that's what you thought I was saying...
Thanks for the reply. I don't know how common a state of anhedonia is and in 60 years I've never heard that term even in psych classes..
BJJ is such a great art, and that reminds me of my Tae Kwon Do days. It may sound funny, but in my mind it wasn't so long ago, although it was 1979-81. If at all possible, and with the importance you put on it, you should do all you can to continue, at least the flex training on your own if it comes to that.
Degenerative disk disease is the same thing I was told, lower back, but I know people way worse off.
For me, after doing a lot of difficult labor in my younger years, to doing a lot of ladder climbing and attic crawling, and now very technical work but still requires being on my feet and moving around, lifting heavy devices sometimes, it's fortunate my ability to change vocations has worked out to match my ability.
It did "sound harsh" the way you described anhedonia, but again, if surgery(s) had a very high likelihood of fixing my pain issues I'd try it, but I think the only solution other than pain management and whatever diet and exercise I can manage would be a TIME MACHINE to go back and avoid some of the things that got me in this situation.
 
Thanks for the reply. I don't know how common a state of anhedonia is and in 60 years I've never heard that term even in psych classes..
BJJ is such a great art, and that reminds me of my Tae Kwon Do days. It may sound funny, but in my mind it wasn't so long ago, although it was 1979-81. If at all possible, and with the importance you put on it, you should do all you can to continue, at least the flex training on your own if it comes to that.
Degenerative disk disease is the same thing I was told, lower back, but I know people way worse off.
For me, after doing a lot of difficult labor in my younger years, to doing a lot of ladder climbing and attic crawling, and now very technical work but still requires being on my feet and moving around, lifting heavy devices sometimes, it's fortunate my ability to change vocations has worked out to match my ability.
It did "sound harsh" the way you described anhedonia, but again, if surgery(s) had a very high likelihood of fixing my pain issues I'd try it, but I think the only solution other than pain management and whatever diet and exercise I can manage would be a TIME MACHINE to go back and avoid some of the things that got me in this situation.
So you also have degenerative disk disease? I'm sorry to hear it's caused you so many problems. Are you able to workout in any way? I ask both for you and myself, but honestly, physical therapy is SUPER important for almost all injuries, so if you don't do any then I'd highly recommend it. Both the pain management doc I just saw and my PT have explained that building the muscles surrounding any injured area is the most important thing you can do to deal with pain and stay functional. I was also told that you can't lower inflammation and build strength at the same time, and that's why my pain doc didn't want to give me a cortisone shot. He explained that NSAIDs actually weaken areas you are trying to strengthen by negating the necessary inflammation from exercise. We NEED inflammation from exercise to get stronger.

I personally am trying not to freak myself out about the DDD because we all get it and I'm very serious about my PT work. Lots of BJJ guys and MMA fighters end up with neck problems and learn to deal with them and continue training, so I'll be one of them. I can't go back in time either lol, but if I could I wouldn't have not done BJJ, which is what caused these issues in the first place. It's too much a part of my identity and what I love.

I don't know why you think surgery wouldn't help for you. I was told it would help for me but only as an absolute last resort. Did a doctor tell you it wouldn't work for you?
 
DDD is fairly common just going by what I hear.
Don't freak yourself out, keep up the BJJ and as I suggested definitely the flex and strength training.
I'm not getting my back cut on unless my pain becomes UN-manageable, and I have painS elsewhere unrelated to my back that meds and 7-OH/pseudoindoxyl erase..for a while...
Like you saidsurgery as a last resort.
You sound like your head is screwed on pretty straight, I'm curious:
What first brought you to the Bluelight forum??
 
DDD is fairly common just going by what I hear.
Don't freak yourself out, keep up the BJJ and as I suggested definitely the flex and strength training.
I'm not getting my back cut on unless my pain becomes UN-manageable, and I have painS elsewhere unrelated to my back that meds and 7-OH/pseudoindoxyl erase..for a while...
Like you saidsurgery as a last resort.
You sound like your head is screwed on pretty straight, I'm curious:
What first brought you to the Bluelight forum??
Thanks. I appreciate it. Yeah, I agree, only do surgery as a last resort. I don't know what "flex" training is but I'll look it up. I just do typical PT.

Well, I find drugs really interesting and always have. I first came on this site about 10 years ago when I was getting my third knee surgery because I wanted to better understand interactions between my prescribed Klonopin and the Oxycodone and Hydrocodone I knew I'd be prescribed. People then told me about Kratom which I got into, as well as Phenibut which i was into for a bit but thankfully stopped (I just don't think it's the best drug to experiment with.)

I mean, there are a lot of different types of people on this forum as you can probably tell. I've met a lot of really intelligent and open minded people here. I also have my own mental health problems like anxiety and depression and a learning disability which makes me neurodivergent, and there's people here who have some similar problems, so I can relate to that.
 
I don't know what "flex" training is but I'll look it up. I just do typical PT.
Flexibility PT. It was a big part of Korean Karate, especially the high kicks. Stretching, stuff that lends to your ability to perform various moves.
I'm sure you know what I mean now.
 
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