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[6-APB Subthread] Adverse Effects / Side-effects

Took 2 Fri night, felt ok after good sleep, most noticable side effect, feels like i have been ripped a new arse hole, wow it burns on the way out!!!! lol
 
Took 1 pellet after an meph/meth/mdai bomb. Don't know what contributed to what but the come-down for me has included:
- For 3 days and counting... rapid resting heartbeat, strange feeling of vibrating in chest when trying to sleep => causing some insomnia, vaguely migrainey and lightheaded, feeling generally quite low, just got a cold to top it all off. Gradually improving though.
- For 2 days... unsettled stomach, vague kidney pain, liquid shits
- The day after... generally felt absolutely awful - but not that much different to the comedown from anything else, apart from my eyes couldn't bear any bright light (or read the mobile).

I really don't like this chemical - or maybe it was the combination of that and the bomb wot has caused the extended -ve crap. And the trip itself was unenjoyably intense as well. Think I'm gonna stick to meph/meth/mdma where the fatigue might last a couple of days but at least the heart and brain shit is over with after one...
 
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Took 1 pellet after an meph/meth/mdai bomb. Don't know what contributed to what but the come-down for me has included:
- For 3 days and counting... rapid resting heartbeat, strange feeling of vibrating in chest when trying to sleep => causing some insomnia, vaguely migrainey and lightheaded, feeling generally quite low, just got a cold to top it all off. Gradually improving though.
- For 2 days... unsettled stomach, vague kidney pain, liquid shits
- The day after... generally felt absolutely awful - but not that much different to the comedown from anything else, apart from my eyes couldn't bear any bright light (or read the mobile).

I really don't like this chemical - or maybe it was the combination of that and the bomb wot has caused the extended -ve crap. And the trip itself was unenjoyably intense as well. Think I'm gonna stick to meph/meth/mdma where the fatigue might last a couple of days but at least the heart and brain shit is over with after one...

No offense - no offense, but taking a novel, potent, sketchily identified substance for the first time after a cocktail of methylone/meph and either MDAI 0r MDMA - your post abouve suggests both - is reckless to the point of suicidal. Someone else is likely to do something similar, the press will blame the new drug, and all this glorious debate with come to an end.

Mixing the 3m's is dodgy enough - adding 6-APB leaves you frankly lucky not to have won a Darwin awared. The genie's probably out of the bottle, and the scene won't last long as is - shit like this is just goint to speed the end.

Sorry to preach, I've mixed plenty of drugs myself - had a rep as a madman - but this kind of behaviour is exactly why governments don't trust us to use drugs sensibly.

So many users don't.
 
6-APB - Reported side effects

Could you please post any side effects experienced. I'm collecting this information on behalf of Erowid, we need to get a vault up ASAP.

Could I also ask to submit trip reports and send me the reference number, I'll get them prioritised.
 
Suppose I'll start...

Euphoria
Sweating
Bruxism
Dilated pupils
Stimulation
General feeling of good will
Empathy
Increased appreciation of music
 
Tiredness and a headache nothin more id get from alcohol...

For all interested its clear the first lot of pellets are under dosed from 100mg...

No doubt about it is the same chem as the samples , wouldn't shoot them down like u like t do scooby most of the intelligent people on ere know your full of it anyway, when I've the time ill pm u. Cos I wanna know what your agenda is


Seejay
 
Took 2 Fri night, felt ok after good sleep, most noticable side effect, feels like i have been ripped a new arse hole, wow it burns on the way out!!!! lol

Yeah man, everybody who I've talked to had some ungodly shits after this, took 4 days for my arse to recover.


I felt extremely fucking low a few days after this, and a friend did too. MDMA never did this, it wasn't just feeling down, it was serious life evaluating stuff. Pretty much wanted to die.
 
No offense - no offense, but taking a novel, potent, sketchily identified substance for the first time after a cocktail of methylone/meph and either MDAI 0r MDMA - your post abouve suggests both - is reckless to the point of suicidal. Someone else is likely to do something similar, the press will blame the new drug, and all this glorious debate with come to an end.

Mixing the 3m's is dodgy enough - adding 6-APB leaves you frankly lucky not to have won a Darwin awared. The genie's probably out of the bottle, and the scene won't last long as is - shit like this is just goint to speed the end.

Sorry to preach, I've mixed plenty of drugs myself - had a rep as a madman - but this kind of behaviour is exactly why governments don't trust us to use drugs sensibly.

So many users don't.

Yeah I have actually learnt my lesson. Had such a shit week that I won't be trying out new things in a full dose, or in combination again.

But I don't think you're really right that "this kind of behaviour is exactly why governments don't trust us to use drugs sensibly". The government will ban it regardless of whether people use it sensibly or not. As soon as it's picked up by the ACMD/related groups or the media, it will be banned because it's psychoactive. Period. And they will already have picked up on this chem because they monitor the RC market.
 
i have asked Felix can i use his post for harm reduction purposes, for peeps here who do not know felix and his better half Kate they are long standing mods at bluelight of mature age ..haha and there integrity can not be questioned

members please take note of this report(s) as it shows the amount from being a nice high to a terrible one can be just one pellet or 100mg at the most.

This is Kate's post

"We had 4 6-APB pellets, the light orange coloured ones. Decided I'd take the risk to try it out and see how it went and I'm glad I did - but have mixed reviews.

We took one pellet each - I was with my partner at home, which is our ideal setting. We are 40 and 44 and have a varied and reasonably wide experience of RC's especially those available in the UK which were banned earlier this year. We both really love our 2C's and psychedelics and have have enjoyed Methylone over all RC's as a particularly good "couple drug". Mdma / decent pills have become incredibly difficult for us to source in Scotland, hence we have opened up to trying new experiences and weighing up the risk of doing so.

Last night we started with one pellet each, crushed up in our mouth at 10.30pm (GMT). No other drugs were consumed though we'd both had a little alcohol.

Within 30 minutes we could feel the effects starting - music appreciation was amazing and I started to dance around to Toots & The Maytals etc, harder dance music was just not hitting my spot! We got chatty and cuddly with each other and started to play around "sexy-like" though my boyfriend could not quite rise to the occasion we both felt naughty and adventurous, ending up playing around in an uninhibited manner of dirtiness. Great fun!

What struck me about this one pellet experience was how smooth and easy it was. So gentle but never quite getting me to the place I wanted to be. Little mini-rushes, lite euphoria, pleasant stimulation. No ill effects - no headaches or nausea. Just fun times, great intimate conversations - but not quite getting there to what we'd really have liked. Unaffected eyesight and a clear head ensured I could even see my BL screen on my laptop! Felt totally in control if I needed to be.

We both wanted to try more - to see where it took us next and if would ramp up the enjoyable effect's we'd been getting.

At 2.20am we crushed and ate the second pellet.

Things changed from here on in - like we'd taken a completely different drug

At 3.00am I could feel my body temperature fluctuate - We decided to go and sit outdoors, look at the trees and stare at the stars in the sky. It felt good to cool down a bit - I was getting unpleasantly hot n' sweaty. The stars started moving around and leaving tracers - swirling away. We have colour changing lights in our garden and they immediately took my attention as the drug changed into a very much psychedelic experience for me. This was great - it was a colourful, easy scene with no head fuckery. Pretty, colourful and engaging shape-shifting, breathing surfaces and intricate patterning.

By 3.45am I started to feel very nauseous my partner started suffering bad jaw clenching that was beginning to distract him. We tried to get some magnesium down him but it had no effect. I could feel it too. Quite quickly we got really fucked - wobbly on our feet, vision very compromised. The visuals were very enjoyable for me but sometimes the whole garden would morph into a breathing cartoon like place. I was totally tripping balls! My partner less so, he was beginning to look agitated and not having such a good time, due to the severe jaw clenching & teeth grinding.

By 4.20am the vomiting started - it came on very suddenly and there was no warning. It was the strangest sickness I've ever experienced - gurgling, windy, acid bile type. Very distressing. I started first (and I can be quite a vomiter on many things) but very soon after my partner started too (very unusual for him). This sickness went on every 15-20 mins or so for the next 7-8 hours. It was horrifying and totally spoiled the pretty psychedelics and energy. By 5.00am we both had really bad headaches and taking ibuprofen did nothing. By sunrise my headache at the front of my head was the most massive migraine, so so painful and quite frightening. It consumed me in-between the constant puking and mad lovely visuals.

I'd been enjoying the psychedelic experience at this dose - it was beautiful and non threatening but totally spoiled by the negative side-effects. There was little joy with so much crap going on physically.

Neither of us had any clue what was going on with our body thermostat - it was all over the place. Sensibly enough we brought blankets into the garden to snuggle up together in. We kept throwing up - within the hour agreed it would be safer to go indoors. I noticed on the 2nd pellet my thermostat was all over the place, I was really unsteady on my feet / walking and could not see properly.

By 6.00am we'd taken to the comforts of our bedroom, still close and hugging but having to still take breaks to throw up. This is what the 2nd pellet experience was most marked for - very sore jaw clenching, major head pain and constant trips to the loo. Relentless and we started to get really fed up. Things were still really trippy for me though he'd stopped.

By 7.00pm we spoke of settling ourselves. We had 7.5mg zopiclones and 1mg xanaxes in the drug box and decided to go for the xanax to smooth ourselves, and lessen the anxiety we were getting about the awful side effects. It took 3 xanaxes each over a 3 hour spell to get us to ease up and nod off.

By 11.30pm we had nausea, painful head and were knackered - the 3rd xanax slowly kicked in, coddling us into some sleep. By mid-day today we slept until 4.00pm.

Now that was a surprising experience for us - the first pellet smoothness and niceness but not quite hitting the spot was lovely. So much so we were driven to continuing the experience by taking the 2nd. This turned into a compete nightmare - a great pity as the visuals were great fun but overridden by the constant vomiting and discomfort. It truly was like taking a different drug.

My conclusion to our wee experiment is - yes, I'd take it again (infrequently) but I would not touch the pellets again. IMHO they are a very bad idea as you have little control over your dose and what actual amounts of active 6-apb's in them. I'd rather wait to see if 6-apb becomes available in powder form so you can accurately measure the dose for yourself.

2 pellets were horrible physically on us - one not enough. Somewhere between those points is a really nice couple drug for us to enjoy.

This is felix's account

"^yep - i was the other half during this experience and we both thought it was important to write up a trip report from people the other users would hopefully trust. :)

but that jaw clenching was the worst i've ever had. i get it pretty bad with methylone and sometimes with MDMA, but this was in a different league. as soon as we took the second pill, it completely ruined the experience for me. i can handle throwing up a bit, but the jaw clenching and teeth grinding went on for HOURS. thank fuck for xanax, that's all i can say.

i must confess that i hadn't even thought of whether this compound is a MAIO, but that's an interesting point.

anyway, the first pill we had was fantastic. i would definitely do it again, but the thought of taking a second one makes me feel nauseous!

cheers."
 
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yeah one thing i find on 6-apb which is quite strange is i prefer listen to slower less hard music where as when i'm on E or amt its always harder dance music.
 
I'm not liking some of the side effect reported here, some are bordering on possibly serotonin syndrome symptoms.

Body temp fluctuations
Vomiting for hours every 30 mins ( much like a migraine side effect - also caused by serotonin release)
Prolonged Diarrhea
Feet and hand spasms (Clonus)

I could go on.

Be safe people.
 
I'm not liking some of the side effect reported here, some are bordering on possibly serotonin syndrome symptoms.

Body temp fluctuations
Vomiting for hours every 30 mins ( much like a migraine side effect - also caused by serotonin release)
Prolonged Diarrhea
Feet and hand spasms (Clonus)

I could go on.

Be safe people.

yeah i ahd been thinking that temperature fluctuations are very worrying as neurotoxicity is massively increased by high temperatures.

i think strong serotonin releasers lead to many side effects, i have had my share in the past mdma/mda/mde/4fmp/methylone/amt/mephedrone/methamphetamine and to be fair mdma and mephedrone had the least rough effects when used in small sensible doses (out of the before mentioned chemicals). MDMA can have a harsh comedown but the reason it was so popular compared to mda (which 6apb is far closer to) is that its euphoria was high and nasty side effects were low while you were on it, it obviously has a rough two day later comedown.

mda was rough in all aspects and never was as mellow and easy as mdma. i was with someone on mda whose legs wouldn't stop twitching and they got excruciating cramp, another friend had horrible halucinations, and to be honest the high was lighter and more like strong speed. this 6-apb sounds so similar:\
 
It could well be that 6-APB exhibits some MAOI activity and redosing exposes this.

Until research is done we will never know.
 
mda was rough in all aspects and never was as mellow and easy as mdma. i was with someone on mda whose legs wouldn't stop twitching and they got excruciating cramp, another friend had horrible halucinations, and to be honest the high was lighter and more like strong speed. this 6-apb sounds so similar:\

well the N-methyl varient will no doubt never see the light of day after this gets banned + N-alkyl substitutions + esters there'of etc etc
 
Aren't alot of these negative symptoms people are describing symptoms for Serotonin Syndrome? :\
 
Yes they are Rick . I also note that a lot are I combination or taking more than one.

Some of them also sound like a classic comedown. I had wackywednesday off these things got through it. Tho some friends have noted higher resting heart rates
 
This is how i commented some of the 6-APB side-effects after my initial trip reoprt: http://www.bluelight.ru/vb/showpost.php?p=8689647&postcount=467

Qualitative comments:
I noticed that 6-APB tends to produce vascoconstriction and really high BP that could lead to a hypertensive crysis. I suspect that these side effects are caused by serotonine intoxication. Other symtoms like
hallucinations, agitation, muscle stiffness or anxiety also correspond to that picture. To solve the issue, there are many meds that cause vascodilatation. Potential counter agents are alpha-blockers, L-arginine, Sildenafil (Viagra), Amylnitride (Poppers). Phisical effort is also very useful, as it accelerates the transformation of L-arginine in NO. NO is used in the whole body to dilate blood vessels. In this case, that happens cause the muscles need more energy from blood vessels, so they have to dilate. But for really getting rid of serotonine intoxication, there is no med is listed in literature (serotonine syndrome). Inspite of this, it was found that Baclofen has a neuroprotective effect in the brains of MDMA treated rats. I Personally found that it does wonders against serotonine intoxication. The same would probably count for GHB, GBL or Phenibut. All are acting in a similar way through GABA-B agonism. Hopefully one time there will be more research on this.
For those who had a bad reaction on 6-APB that was maybe caused by serotonine intoxication, keep in mind that the intoxication symtoms could worsen if:

Endogen dopamine is depleted from bingeing with srong dopaminergic stimulants (Meth, Meph, Cocaine, Speed ect). Endogen Dopamine and Serotonine tend to be in a balance through an autoreceptor mechanism. If Dopamine is absent, more Serotonine will be released and vice-versa.

The man/woman in case has an unhealthy diet. In that case essential amino acids like L-arginine are insufficient to dilate the blood vessels again.

No physical effort is being done during the trip. Maybe some of you know the impression that everything is darkening around you when lying on the couch on a hard tryptamine trip. When you get up and walk araund a little you migt instantly feel fine again.
 
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