I thought I remember there being reports from way back when of synthesized baeocystin (4-po-nmt) being active on its own. Given that's true, and that the 4-ho-NMT that I've IM'd, Dondante's IV'd (meaning it's not MAO that's the problem), and numerous other people have swallowed to little effect was legitimately 4-ho-NMT, that "po" could make a big difference for other tryptamines.
Regarding 4-ho/AcO-DPT (if it's truly out there now), I'm cautiously optimistic. It would be amazing if it inherited the power and utter uniqueness of DPT the same way 4-ho-DMT does in regards to its dad. Here's hoping something actually comes of the hearsay this time around.