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5-htp question

Don't take 5-htp before rolling, it will diminish your roll, possibly even make you not roll at all. Post-load with 5-htp to rebuild up serotonin, pre load with piracetam.
 
reason y i asked is my friend had heard 5-htp is good for anxiety/depression, so hes been taking 100mg a night for 5 days now, and plans rollin on saturday...if he doesnt take it tonight, tomorrow or saturday is he good to go for saturday? or is serotonin syndrome risk? sorry shoulda been more clear
 
gnarleyonaharley said:
reason y i asked is my friend had heard 5-htp is good for anxiety/depression, so hes been taking 100mg a night for 5 days now, and plans rollin on saturday...if he doesnt take it tonight, tomorrow or saturday is he good to go for saturday? or is serotonin syndrome risk? sorry shoulda been more clear
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as long as he stops a few days before, he is fine.
So it sounds like he will be ready to roll.

If he is suffering from anxiety and depression, rolling might not be the best thing for him, as it depletes serotonin, which can lead to more depression.. but i guess that is another topic of it's own.
 
gnarleyonaharley said:
reason y i asked is my friend had heard 5-htp is good for anxiety/depression, so hes been taking 100mg a night for 5 days now, and plans rollin on saturday...if he doesnt take it tonight, tomorrow or saturday is he good to go for saturday? or is serotonin syndrome risk? sorry shoulda been more clear
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Have him stop now, and he should roll. People usually stop a week to a month before they roll just to be safe, but you should be fine

No Consequence said:
If he is suffering from anxiety and depression, rolling might not be the best thing for him, as it depletes serotonin, which can lead to more depression.. but i guess that is another topic of it's own.
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Think of this too ^
Depletion of serotonin causes depression in itself, and anxiety before and after. has your friend rolled before?
 
he's always had anxiety tho, even before ever rolling so whatever that doesnt seem to bother him haha...but i got freaked out so i told him not to roll bc i hear about serotonin syndrome with that combo...i told him to discontinue it today tho, so he wanted to drop saturday night and the last time he took the 5-htp was wednesday... i will give him go ahead unless anybody else thinks this is a bad idea
 
gnarleyonaharley said:
he's always had anxiety tho, even before ever rolling so whatever that doesnt seem to bother him haha...but i got freaked out so i told him not to roll bc i hear about serotonin syndrome with that combo...i told him to discontinue it today tho, so he wanted to drop saturday night and the last time he took the 5-htp was wednesday... i will give him go ahead unless anybody else thinks this is a bad idea
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It should be fine as long as he stops taking the 5-htp.
 
Sooo, what if you stopped the day before? Is there anyway to kind stop the effects of the 5htp so soon? Could I like drink a ton of water all day before I roll and have it work? I wasn't aware that 5htp made you not roll. D:
 
exm said:
Sooo, what if you stopped the day before? Is there anyway to kind stop the effects of the 5htp so soon? Could I like drink a ton of water all day before I roll and have it work? I wasn't aware that 5htp made you not roll. D:
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I wouldn't take the chance of stopping the day before, it could end up just being a waste of the MDMA.
 
5HTP is extremely soluble. It's half-life in the body is roughly the same as MDMA. So wait 2-3 days. Minimum.

Always take 5HTP *after* your event, in normal doses. Loading your body up won't do any better than following a dosage.

It's like everything else, you can only absorb and process so much before the rest goes to waste.

Anyone feel free to disagree, but here is my "best practice" advice:

Don't take it 3 days beforehand, and take it for 3 days afterward.
 
Chances are it won't "kill" it completely if you stop taking it the day before, but try to have just a little patience and don't waste the experience - There are a lot of us who haven't seen x is a long time, and would be very sad if people weren't using it to it's full potential!!
 
5HTP is extremely soluble. It's half-life in the body is roughly the same as MDMA. So wait 2-3 days. Minimum.

Always take 5HTP *after* your event, in normal doses. Loading your body up won't do any better than following a dosage.

It's like everything else, you can only absorb and process so much before the rest goes to waste.

Anyone feel free to disagree, but here is my "best practice" advice:

Don't take it 3 days beforehand, and take it for 3 days afterward.
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When pre-loading (or post-loading) with 5-HTP, always make sure you do it on a full stomach or with a medium-to-large sized meal.
 
Ok I am confused now...I thought preloading w 5-htp a few days before rolling could lead to seratonin syndrome which is y I started thread, now I am under the impression that it will make u not roll? Someone please explain...
 
5-HTP can cause serotonin syndrome in rare cases (it's happened to me, horrible horrible experience, which is why I recommend only taking 5-HTP on a full stomach), as far as it "dulling" the roll, that depends on who you ask.

I've preloaded with 5-HTP for tripping on LSD and it caused favorable results. I've never tried it with MDMA, however.
 
Sorry to add to the confusion. Here is *my* experience:

Taking the day of has ruined my roll twice. I did not take due diligence and research what I had heard, and was told 5-HTP would skyrocket my roll. It most definitely caused adverse effects.

That is how I define "preload" as it was passed to me: Taking 5-HTP the day of, or the day before the roll.

But - as a precursor, your body still has to process what you give it.

Here is how I look at it:

Everyone's body is different. Multiple people say it dulls -in my case twice virtually canceled- the roll. I don't like to throw time and money and the experience down the drain. So, do a tiny bit of your own research out there.

How will you know if it effects you personally? To be perfectly frank, you would just have to do it and find out.

I say, play it safe. If you take 5-HTP before had-do it long enough in advance that it will have processed in your body- Hence *my* "3-Day" rule.
 
Ok so am I correct in saying that by not taking it the day of the roll or the day before the roll you will not be at risk of serotonin syndrome AND will have a better chance of not dulling your roll? My concern wasn't him dulling the roll with the 5-htp but putting himself at higher risk for S.S.
 
I rolled on SSRIs after taking .9 g's of 5htp daily for a month and I way sniffing coke, I never got serotonin syndrome.. But if your worries avoid it a day or two before your drop.
 
Serotonin syndrome can come from a lot more than 5-HTP. Synthetic opioids for example - hydrocodone, st johns wort, etc. and the symptoms can range from nothing to...the badness.

Personally, if you want to avoid being at risk, I would say the following:

Avoid overloading yourself on 5-HTP period. Take normal doses. That in itself will reduce your risk exponentially. Severe S.S. is kinda rare as it is. Not to say throw caution to the wind -

But I -personally- believe if you stop taking it beforehand and take it in normal doses afterward, you shouldn't be overly worried.
 
Thanks for input everyone...after doing some research, it is my understanding that the risk of S.S. is increased when you COMBINE mdxx and 5-htp (as in take them same day or same time)...the doseage of 5-htp in question was for 5 days at 100 mg a night...
so i guess stopping for 2 or 3 days before the roll would be ok considering the half life of 5-htp is somewhere between 90 min and 7 hr...

this sound good in the interest of harm reduction?
 
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