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4-ho-5-meo-mipt, 4-ho-5-meo-dipt?

L

lostreality

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well there is talk of the possibility of 4-ho-5-meo-dmt by adding 5-meo-dmt to mushroom substrate.

Do you think that the same could be done with 5-meo-mipt and 5-meo-dipt?

Do you think that these substances are possible to create?

Do you think they may even have value?
 
Can anyone theorize what they would be like?

Would they take on a more generic 4-substituted-T feel or would they retain the feel of their respective bases (foxy and moxy)?

I'm interested. If I ever try this though it would definitely be with 5-meo-dmt.
 
Also, does anybody know the ratios of 5-meo-dmt to substrate one would add? I've heard if one adds too much tryptamine to the base then it can shut down synthesis in the fungus.
 
Tryptamine may be added to a degree far beyond the limits of the enzymes naturally present to process them without any negative effects. One gram of tryptamine per quart jar of spawn produces fruits with potency of 3x to 4x that of the untreated jars.

A person attempting to make a novel tryptamine would want to completely saturated the synthetic pathways with the novel tryptamine precurser to ensure that the target compound was the only one being produced. So adding a gram to a quart jar of spawn, and then casing the spawn directly instead of using a bulk substrate would be most effective to prevent other competing tryptamines from being synthesized and producing a mixture of 4-ho-dmt and the target compound.

To know the exact ratio a person could make say ten jars of spawn with varying amounts of tryptamine and then test the resulting fruits for potency. The first jar to have a drop in potency is obviously near the saturation point which could then be used to determine how much 5-meo-dmt needed to be added to saturate.

Any added compound should be ph 7-8 before being added.

^If you have any links to that information it would be appreciated :)
 
a whole gram per jar? that seems crazy. you could trip 50 times off of a gram of dmt, why would you want to use that much to make a quarter of mushrooms 3x more potent?


i could see that with dpt or someshit, but what about 5meo-dmt or dipt
 
kong said:
Tryptamine may be added to a degree far beyond the limits of the enzymes naturally present to process them without any negative effects. One gram of tryptamine per quart jar of spawn produces fruits with potency of 3x to 4x that of the untreated jars.

A person attempting to make a novel tryptamine would want to completely saturated the synthetic pathways with the novel tryptamine precurser to ensure that the target compound was the only one being produced. So adding a gram to a quart jar of spawn, and then casing the spawn directly instead of using a bulk substrate would be most effective to prevent other competing tryptamines from being synthesized and producing a mixture of 4-ho-dmt and the target compound.

To know the exact ratio a person could make say ten jars of spawn with varying amounts of tryptamine and then test the resulting fruits for potency. The first jar to have a drop in potency is obviously near the saturation point which could then be used to determine how much 5-meo-dmt needed to be added to saturate.

Any added compound should be ph 7-8 before being added.

^If you have any links to that information it would be appreciated :)
Click to expand...


No way am I going to add a gram of 5-meo-mipt into a quart jar. I was thinking more along the lines of 100 mgs in a half pint jar. I think that amount would be sufficient to determine if 4-ho-5-meo-mipt was actually made.

It appears that none of this stuff has ever been done only theorized. Its quite surprising. Every one brings up the topic and gets excited but no one does anything. I will not be doing this for a while but if I ever do, I'll be sure to inform the public. Maybe I'll become one of those that never does anything either.
 
Have you got the equipement to test if 4-OH, 5MeO DMT is made, or would you just tase it and hope? I would wonder if that 5MeO would prevent the 4-OH from being formed...
 
I do not have the equipment to test anything. In all honesty my little experiment would prove nothing conclusively. But my curiosity is eating away at me.
 
if you go the the shroomery message boards, there are advanced mycologists that can tell you how to do it (and they have done it)
 
A gram of tryptamine costs less than a dollar. A quart jar of spawn can produce over an oz if cased properly. A couple quart jars can put out a pound if spawned to bulk. A couple dollars worth of tryptamine seems worth the cost to me.

As far as I know the only reactions that have been proven to work are those add 4-ho to tryptamines with no 4/5 position groups. Most people who can get dipt for instance can also get 4-ho-dipt which is why few people try this.

Adding tryptamine by the gram is incredibly cost efficient:)
 
If you'll read Shulgin's notes about the experiment in Europe (somewhere?) he noted that in the early stages they realized adding too much of tryptamineX would cause synthetic pathways to completely shut down and NO alkaloids would be produced.

Also, adding the right amount of DPT caused 4-ho-DPT to be produced and ONLY 4-ho-DPT (ie the mushrooms pathway for 4-ho-DMT was shut down). In this way you get legal mushrooms (presuming that your country hasn't schedule 4-ho-DPT).
 
Interesting, 1 gram tryptamine added to quart jars of spawn, spawned to straw and shit doesn't reach this point.
 
kong said:
A gram of tryptamine costs less than a dollar.
Adding tryptamine by the gram is incredibly cost efficient:)
Click to expand...

maybe you can get grams of tryptamines for a dollar, but i sure as hell cannot,
And i assume many others here are in the same boat as me.
What do you buy 10 kilos for 10,000 bucks?
 
actually MANY chem companies that WILL sell to individuals will sell tryptamine in standard quantities as it is a very common product you can buy any amount and it's still very cheap, 10kgs would cost way less than $10gs. Or you could get tryptophan and decarboxylate it which is fairly simple. But I wonder if the shrooms can naturally decarboxylate tryptophan as it is found in small quantities in shrooms, perhape you could just add that too the medium and the shrooms will handle the rest.
 
I have heard there are issues in adding nitrogenous stuff to mushroom substrates whether they are psychedelic or not, the more nitrogen the 'hotter' the substrate and the more likely it will contaminate before the colonisation is complete. The Dutch growers found this was a problem going from grain spawn to bulk compost, when the grain spawn was supplemented with tryptamine or tryptophan supplements.
 
Well using shit is fairly common practise, shit being full of tryptophan and nitrogenous compounds. It is more difficult to colonize vs straw ect....

Using tryptamine supplemented spawn to straw isn't more prone to contamination than using shit, (as far as I know).

Tryptophan is cheap, not tryptamine.
 
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