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4-F-MABP, 4-MeO-PBP, 4-Et-PBP, 3-Me-4-MeO-MCAT, 4-Me-EABP

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4-fluoro-methylaminobutyrophenone will be good dopaminergic stimulant with dosage around 100 mg
4-Ethyl-Pyrrolodinobutyrophenone - may be an active stimulant in 100 mg range
4-Methyl-ethylaminobutyrophenone - can be NE reauptake inhibitor

but is is all I guess
I have tasted 4-f-PBP it is active stimulant in 100 mg dose
 
Whats the matter with all theese beta keto designer drugs? In my opinion there is nothing that special about it and it tends to make the drug even more anxiogenic and hypertensive apart from making the molecule much more hydrophilic and by so less prone to cross the BBB easily (also they turn into beta hydroxys very quickly...which is crap).

MMA is a good non neurotoxic MDA substitute, it hit the strees around the same years even here in Italy where other RCs never did. David Nichols studied it again in the 90's and from what I've heard so far it was very appreciated by most users. A N-methylated version would surely be very promising. 5-methyl MDA is also a winner among many RCs.
I just don't get all this obsession around beta ketos.

BTW could someone explain to me what pros and cons does the N-pyrrol have over the N-methyl?
 
/navarone/ said:
But what about dopaminergic action?

So if whe where to compare N-methylamphetamine and N-pyrrolamphetamine which in your idea would show more interesting properties?
Click to expand...
The N-pyrrol turns the compound from a crappy NDRA into a decent NDRI. Large beta- substituents are desirable in phenethylamine-derived NDRIs (see also desoxypipradol and methylphenidate), but not in phenethylamine-derived NDRAs. See also alpha-pyrrolidinopropiophenone

EDIT: Should have clarified that this only applies to cathinones. Amphetamines are perfectly suitable NDRAs.
 
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Are you discussing modifications beginning with a methamphetamine skeleton?
If so, I can't agree, as MDPV and Naphyrone appear pretty shitty, and meth a worthy if unwieldy DA releaser.

ebola
 
yea but you cant compare beta ketos with normal amphetamines, I guess /navarone/ asked about non beta keto pyrrol's
 
So according to wiki pyrrol amphetamines destroy almost fully any kind of serotonergic activity hency why MDPV, α-PVP and other 3,4 conjugated pyrrol amphetmines seem to show negligible serotonergic activity....
The only one that does is naphyrone though there have been some carcinogenicity claims about it.

Kida sucky isn't it?
 
Hi,

I will give some update on those Cathinones.

I bio assayed myself some and the result was :

4-Me-EABP (4-Methyl-(ethylamino)butrophenone) or 2-(Ethylamino)-1-(4-methylphenyl)butan-1-one

Around 2x+ the potency of 4-MMC, the effects are
quit similar and the duration is almost the same, quite euphoric. Interesting compound.

4-F-MABP (4-Fluoro-(methylamino)butyrophenone) or 1-(4-Fluorophenyl)-2-(methylamino)butan-1-one

Much less potent as 4-MMC, I didnt work more with this one yet.

Don't take this at is, always start the lower you can and work up. Those was untested compound but I have the certification it is the right chemical 99.5% pure.
 
Lawrence said:
4-Me-EABP (4-Methyl-(ethylamino)butrophenone) or 2-(Ethylamino)-1-(4-methylphenyl)butan-1-one

Around 2x+ the potency of 4-MMC, the effects are
quit similar and the duration is almost the same, quite euphoric. Interesting compound.
Click to expand...

Sounds good but surely banned in UK...
 
4-Me-EABP (4-Methyl-(ethylamino)butrophenone) or 2-(Ethylamino)-1-(4-methylphenyl)butan-1-one

Around 2x+ the potency of 4-MMC, the effects are
quit similar and the duration is almost the same, quite euphoric. Interesting compound.
Click to expand...

I wonder how this comes making the molecule even more bulky then 4-MABP makes it more potent? while 4-MABP is already weaker then mephe and also 4-mec wasnt very potent too.

What I think could be a good meph replacement (and maybe more potent) would be the 4-ethyl homolouge of buphedrone, 4-ethyl seems to give it quite a plus on serotonine and buphe is a very potent dopa releaser.
 
What I think could be a good meph replacement (and maybe more potent) would be the 4-ethyl homolouge of buphedrone, 4-ethyl seems to give it quite a plus on serotonine and buphe is a very potent dopa releaser.
Click to expand...

But an alpha chain as long as buphedrone's tends to abolish DA releasing activity while enhancing DARI activity.
 
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