4,5-hydroxy-dextro-Methamphetamine..........possible effects

[/navarone/]

I was wondering on the possible effects of this substanze conpared t the ususal d-methamphetamne.

Those two hydroxyl groups shoud give a higher affinity to the dopamine receptor increasing the potency of the drug.
I'm obviously talking about the d isomer

it would be like MDMA but without the carbon bonding the 2 oxygens.

Could anybodygive my any information about the affectsand the potency of this drug?

Something tells me its more potent thatn d-meth be cuz it has a higher affinity ti the dopamine receptor, but im not competent on the subject so im asking you guys.

It's widely knows that the addition of a methyl group to the amine in the molecule potentiates incredibly the effect of the amphetamine.
and probably the molecule could be metabolized more easily by the oranism.

Anyone could give any info n the subjet.
theoretically this substanze coul be made by hydrolising that carbon bonding the 2 oxygens of the methoxygroup of MDMA.
But i gues a strong oxidizer could affect the amine group.

Btw sorry for the typos but im currently of Clonazepam

Any information would be greatly apreciated.

the molecule should look like thi:

HO N
\ / \ / \/ \
| O | | CH3
/ \ / CH3
HO

Man in tripping tha fuck out...........lol

 

[wungchow]

The polar hydroxyl groups would prevent this compound from crossing the blood-brain barrier in any appreciable quantity. And even if it could cross the BBB, it would have a whole host of nasty peripheral side-effects.

Wouldn't touch it with a 20-foot pole.

 

[UnfortunateSquid]

alpha,N-dimethyldopamine?

No-fucking-thanksmate.

Btw, 3,4-hydroxy- is the correct prefix, rotate around the Phenyl-C bond to minimise the numbers.

 

[/navarone/]

so what would be a way to have something in between dopamine and methamhetamine?

BTW is there any stimulant stronger than meth?

 

[/navarone/]

actually what would u expect if u manage to put a nitrogen or a sulphur betwer the 2 oxygens in MDMA?

 

[wungchow]

An MDMA analogue with a sulfur atom replacing the methylene group would be impossible to make (unstable.)

Replacing the methylene group with a nitrogen would probably yield a compound stable at room temp, but would wreak havoc on your body, most likely donating free radicals and/or NO.

 

[hugo24]

Looks eerily close to some neurotoxines.

 

[<pyridinyl_30>]

2,4,5-trihydroxyphenethanamine (6-OH-DA) is a potent, well-known neurotoxin.

The best thing to do with 3,4-di-hyrdoxymethamphetamine is O,O-dimethoxylation.

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