3,4,5-trimethoxy tryptamine

[IGNVS]

anybody ever thought of this? it works for phenethylamines why not try it with tryptamines.

pritty much just the idea of adding more than one MeO group to it, then of course trying out all the things u can add to the nitrogen (methyl, dimethyl, ethyl, isopropyl all that shit). is there any reaserch on anything like this out there i googled it and found notthhinnggg, and ive never heard of it before, can anybody point me out some papers out there on it or anything like that?

 

[Dr.Heckyll]

5-Substituted tryptamines are generally inactive.

 

[Trogdor]

What happens if you take say... 5-MeO-DMT and put methoxy groups on 3 and 4? I believe this is along the lines of the OP's thinking.

 

[IGNVS]

yeahhh just like that... anybody know any chemists?

 

[Trogdor]

I just noticed the positions on tryptamines don't correspond properly to phenethylamine positions. For example, substitute anything on tryptamine's 3 position and you won't have an amine chain anymore.

 

[nuke]

Inactive (and very unstable).

What happens if you take say... 5-MeO-DMT and put methoxy groups on 3 and 4? I believe this is along the lines of the OP's thinking.

My guess is there's some activity. Probably better off making 4,5-DiMeO-MiPT instead of 4,5-DiMeO-DMT though.

 

[IGNVS]

well sure variations are welcome im just introducing the basic idea. trogdor your right i was hoping noone would catch that 8( i shuld have taken a look at the diferent positions before i posted.
im kinda new but how would i turn this into a thread where people post intresting tryptamine ideas and maybe atract some people that can make it posible

 

[fastandbulbous]

There's a thread 'psychedelics of the future' somewhere (don't think it's been archived). Find that and try your question there - might even have some suggestions already.

 

[Trogdor]

Probably better off making 4,5-DiMeO-MiPT instead of 4,5-DiMeO-DMT though.

Going back to what dr. heckyll said, 4,5-DiMeO-MiPT might be a waste of time as tihkal says that 5,6-DiMeO-MiPT is inactive.

 

[nuke]

Au contraire, 4,5-MDO-DiPT is active, so it's my guess that 4,5-DiMeO-MiPT is too (if not moreso).

 

[Dr.Heckyll]

5-Substituted tryptamines are generally inactive.

Ups! I got confused. Of course 5-substituted tryptamines are active.

The problem lies in the " 3,4,5-trimethoxy tryptamine" which is inexistant and should be called 4,5,6-trimethoxytryptamine.

Then my statement should read "6-substituted tryptamines are generally inactive."

 

[Trogdor]

Ah. In a semi-related question, why do tryptamines have two N positions while phenethylamines only have one?

 

[Dondante]

They both actually have two. Well for any non-ring bound nitrogen, two makes it an amine base, and three would make put a charge on the nitrogen. The phens usually just have two hydrogens (which usually don't get drawn on), because carbon substituents take away from psychedelic activity (e.g. MDA to MDMA). I think there is a PIHKAL mention of this effect on 2C-B.

Tryptamines OTOH are usually not active w/o the two substituents. There are exceptions (AMT for example).

 

[Don Luigi]

I searched and could not find the 'psychedelics of the future' thread can anyone give me a link please? Thanks

 

[IGNVS]

yeah that would be cool i was lookin for like thirty muinets and couldnt find it either

 

[Trogdor]

Have you tried utfse'ing? I did, but all I got was a blank screen, because certain things don't work well with Opera Mini, and that's one of them.

 

[djfriendly]

I believe that the thread is called "RCs of the future," and that it is in PD.

 

[IGNVS]

thanks man

 

[djfriendly]

I think this is what you're looking for:

http://www.bluelight.ru/vb/showthread.php?t=243867