OP: "So I get home after a day with my friends and realise the postman has a been a nice chap and delivered me a grey package. Open it and it is the sample of 2-methyl-2-butanol (2M2B herein) I ordered.
After a bit of research I've been doin' I realised its potentially carcinogenic and incredibly potent (35x more potent than alcohol infact).
I am yet to open the vial which contains 10ml and I was wondering if anyone has taken it and if it is worth doin' so?"
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Info taken from psychonautwiki.org
It is strongly recommended that one use harm reduction practices when using this substance.
- @deficiT
After a bit of research I've been doin' I realised its potentially carcinogenic and incredibly potent (35x more potent than alcohol infact).
I am yet to open the vial which contains 10ml and I was wondering if anyone has taken it and if it is worth doin' so?"
______________________________________________________________________________________________________________________
Info taken from psychonautwiki.org
Class Membership | |
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Common names | 2M2B, 2-methyl-2-butanol |
Substitutive name | 2-methyl-2-butanol |
Systematic name | 2-methylbutan-2-ol |
Psychoactive class | Depressant |
Chemical class | Alcohol |
Oral | |
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Dosage | |
Duration | |
Threshold | 0.5 mL |
Light | 1 - 5 mL |
Common | 5 - 10 mL |
Strong | 10 - 15 mL |
Heavy | 15 mL +There have been unconsciousness and deaths reported at as low as 18 mL respective 29 mL.[2] |
Total | 8 - 14 hours |
Onset | 10 - 50 minutes |
Peak | 6 - 8 hours |
Offset | 4 - 6 hours |
After effects | 4 hours |
Toxicity and harm potential
The toxicity and long-term health effects of recreational 2M2B use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown although the lowest recorded fatal dose in a human is 30mL. However, 2M2B is expected to be less toxic than ethanol as it cannot be metabolized into aldehydes in the same way. Anecdotal evidence from people who have tried 2M2B within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed).It is strongly recommended that one use harm reduction practices when using this substance.
Pharmacology
2-Methyl-2-butanol inhibits binding to a proconvulsant site on the GABA receptor which causes negatively charged chloride ions to enter neurons and increase the amount of excitation necessary to cause the neurons to fire. As it is a tertiary alcohol, it cannot be metabolized by alcohol dehydrogenase into aldehydes (which cause the hangover associated with consuming large amounts of ethanol). This makes 2M2B significantly safer than primary alcohols. However, a consequence of this is that 2-methyl-2-butanol has an extended duration of action with effects which last up to 12 hours after its consumption.- @deficiT
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