I have done mushrooms and then done 2ce and got tolerance. I have not however done 2cb, though I have experienced toelrance from 2ce on many situations.
Indoledreamstudies, I am impressed the OP said it was not for everyone, but he could have been downplaying the negative effects, but if he didnt get any good for him that is something to take into account, but with out scientific intentions its hard to say. But just because he cant feel any negatives dont mean he didnt get any.
All of the people I know that have tried 2cb say it is much more recreational than 2ce, but really 2ce gives me what I want out of the psychedelic experience but 2cb is defiantely my next new drug, besides DMT.
Is it possible that tolerance is less through insuffilation than oral? I cant see it
I just want to add that when I was younger I used to dream of trying 2cb from what I read it sounded like all of the good visuals of acid, euphoria of MDMA and none of the bad. But now that Ive done other 2cs many many times, I know that was a more Eutopian ream, there are no perfect substances, and the 2Cs Ive done IM sure are very similar to 2CB, and I could go with out trying it and be just fine!