Weed pretty much intensifies any psychedelic experience in my personal experience. I'm not sure about the 2c's you're talking about doing but I've smoked weed on 2c-e, 2c-p, and 2c-b and they were all a great time. I found on 2c-e though if I smoked early in the trip I needed to continue smoking throughout the trip if I wanted to keep my visuals and my body high at decent levels, but at high doses I found smoking early in the trip made my visuals so much more intense some might find it overwhelming.