25i-nbome tonight then LSD on sunday

[rollonsafely]

any idea what kind of tolerance issues i may have for sunday? how strong, if any, is nbome and LSD cross tolerance? just for some back story i have had 25i once and LSD once, and i am sure the substance is as stated.

Thanks alot,
rollonsafely

 

[daytryptr]

The 25i will fuck with your tolerance big time. Its a hardcore 2a agonist, and imho thats why it has such a persistant tolerance. LSD is pharmacologically much more interesting (all kinds of 5-ht's at normal doses, mild dopamine activity, etc), but still hits 2a pretty hard. Just not like nbomes where it down-regulates the fuck out of 2a since thats the one its hitting for the most part.

If anything, i'd take the lsd first, then the nbome a few days later. LSD tolerance is on par with the classicals imho/e, nbome tolerance/cross tolerance with other psychs can be redickalis.

 

[rollonsafely]

thanks for the info, i figured as much. ill hold off on the nbome till later as my dance with lucy is for a very special occasion :D

 

[Jesusgreen]

Since your question has been answered I'm going to close this. Enjoy your trip with lucy! :D

Closed.