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  • Trip Reports Moderator: M!$ter-ED

~240ug 25E-NBOH nasal spray trip report

6apebillen

Greenlighter
Joined
Jan 7, 2026
Messages
16
PREFACE
So a bit before the 2025 Phenethylamine Ban in the Netherlands I bought a bunch of 25E-NBOH out of curiosity and because it was dirt cheap (not even 50ct per dose) in the form of (supposedly) 1.2mg blotter papers with a strawberry on each one.

After some research I found that nasal dosing works quite well for this compound group that is 25x-NBOx - albeit with the proper (VOLUMETRIC) measurement. So I prepared a nasal spray by leaving 10 blotters in a nasal spray bottle with water, PG and a little bit of alcohol. I left the blotters in there for a couple months probably, and fished them out just before using it for the first time.

The bottle would spray about 100 times before it’s completely empty, which leaves me with an approximate dose of 120ug of 25E-NBOH per spray. I found a user on reddit who did about the same thing, and followed their example.

There were a couple of reports on erowid, but as far as I know there are none of the nasal ROA, so I volunteered myself to guinea pig.

Expectations were: strong visuals, strong stimulation but manageable headspace. This seems to be a shared palate of all the 25x compounds as far as my research goes.

The biggest unknown here was the duration, as I couldn't find any strong consensus on the duration of this stuff with buccal ROA, let alone nasal.

Buccal should last 6-8 hours from what I’ve heard, so I assumed that nasal would be shorter, or the same length. The latter turned out to be true.

Apparently people get quite crampy on this compound group so I took a generous amount of magnesium supplements about two hours before starting.

LIVE REPORT NOTES
[06/02, 18:06] T+00:00 25E-NBOH 120ug nasal, will check back in 20 mins to take more maybe

[06/02, 18:19] light visual acuity change
[06/02, 18:20] vision a bit hazey, lights look brighter and a bit washey
[06/02, 18:20] slight stimulation
[06/02, 18:20] could be nerves

[06/02, 18:33] need to shit
could be nerves
[06/02, 18:33] its for sure doing something but very quite subtle
[06/02, 18:34] might take a bit more in a couple minutes

[06/02, 18:37] 25E-NBOH + 120ug nasal

[06/02, 18:49] very quite stimulated now
[06/02, 18:49] some tension in muscles, fast typing, slight high feeling

[06/02, 18:57] sweaty hands

[06/02, 20:09] feels much like 2cb
[06/02, 20:09] visual haze sorta but not on a level of geometry (yet) could go there at some point

[06/02, 22:30] watching a movie, cognitive space is very slight
[06/02, 22:31] feeling like i'm very hungry in a weird way, tense stomach i guess, i could eat 3 meals
[06/02, 22:32] stomach receptors confused
[06/02, 22:32] not in an annoying way necessarily

[07/02, 01:22] pretty much came down now i think
[07/02, 01:25] slightly stimmed still but overall nice not too crazy
[07/02, 01:25] the dose was good too
[07/02, 01:25] next time could go twice as high without (much) issue, probably some intense body load
[07/02, 01:26] but im pretty curious what the 25x-NBOx visual hype is about
[07/02, 01:26] feels not too toxic this


NEXT DAY NOTES
Around 02:00, I smoked some weed, and this for sure brought back some psychedelia (quite strongly so). Interesting to see that after 8 hours it was still active even with the nasal ROA. I saw some inconsistent reports about the duration of this stuff, but good to know how long it can last.

Also about the weed, I was expecting for it to calm me down a bit, as it was a quite heavy indica strain, but as well as reactivating the psychedelia it also reactivated much of the stimulation of the 25E-NBOH.
This makes me wonder if it does the same with some other more stimulating psychedelics. With psilocybin mushrooms I feel that weed generally increases the lethargic feeling that you get with mushrooms.

Something super interesting I found about the headspace is that there was for sure a 'psych space' but in a super clear headed way, even more so than with lsd or even 2cb.
2cb lacks this 'high definition', conceptual thinking for the most part and feels a bit more hazey. LSD has this high def super brain thinking part, but also gets loopy/confusing. This stuff seemed to be able to get this improved visual/conceptual thinking without any of the confusion, feels like that could be due to how stimulating it is. It felt quite amphetamine-like but with a clearly identifiable psychedelic element.


IMPORTANT NOTE ABOUT DOSAGE
The blotters I made the nasal spray from are supposedly a lot weaker than marketed, so the assumed doses of 120ug per spray could be a lot lower. These doses worked for me but Your Miles May Vary!
Find a threshold dose and work your way up, keep in mind comeup time before redosing.


DAY AFTER EFFECTS
Barely notice anything different, actually nice amount of energy for the limited amount of sleep I got. The 4 beers I had the night before this had more of an impact.


OVERALL IMPRESSIONS
Interesting stuff, pretty 'practical' psychedelic. I played a bit of guitar before watching the movie and found it very easy to get into a groove and sort of imagine layers on top of what I was playing, I think taking some time for making music on this and recording some stuff would be super fun.
Dosage wise, next time I will probably take a bit more. Had a little bit of a crampy feelings in my limbs and jaw, and some uneasiness in my stomach, but nothing alarming or overly uncomfortable.
Curious to see where the balance of (over)stimulation and psychedelia is exactly and how this interaction changes with different dosing. With this dosage I think the stimulation took the overhand a bit.
 
Would like to update to add that towards the evening of the day after I totally crashed, mood was fine but physical energy sorta dropped to 0 around 20:00.

So I think the energy I had during the morning/early afternoon was probably due to some residual stimulation, something I'm pretty prone to with any stimulating compound.

So yea, do this early in the day if you don't wanna be useless the next day :')
 
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