2,5-dimethoxybenzyl Bomamine analogs

[Cortexiphan]

^ good point, let's just skip the anilines i'm in no hurry to try them

 

[sekio]

Another caveat is that O-methylated phenols go only as far as a "plain" phenol metabolically, whereas anilines are further oxidised to aromatic nitroso and nitro compounds - suspected genotoxins.

 

[Cortexiphan]

Wow thanks, how did we all miss that one! Compound 4.7 is one of the most exciting structures I've come across in a long time

The paper just came out, I posted it in the ADD Journal Club