• N&PD Moderators: Skorpio

2,5-dimethoxy-4-astatophenethylamine (2C-A)

halogen in lighting is usually a reference to the use of iodine and or bromine in combination with a tungsten filament, the iodine has the effect of reacting with the boil off tungsten to make a tungsten iodide which diffuses back to the hot filament where it decomposes to give tungsten again. the halogen recycles the tungsten back onto the filament preventing it from coating the inner surface of the bulb allowing the bulb to run hotter and longer.
 
slightly off topic but still in the groove of things... what about silanyltryptamines? DST, aST
 
^^^

organosilicon compounds are generally too unstable to use as drug molecules, the only time you can use a silicon in practice is to replace a quaternary carbon single bonded to 4 other carbons, which is a fairly unusual motif in recreational drug molecules....

The 4-position of the piperidine ring in ketobemidone is a suitable quaternary carbon, so you could replace that with a silicon and most likely retain both activity and stability, but I can't think of any psychedelics offhand that have a quaternary carbon atom that could be replaced with silicon.
 
You'll be lucky! Astatine is an extremely rare element. Its thought that only 30 grams exists within the earth (thats about an ounce). Although no doubt some has been produced in laboratories, it would be a very labour intensive process bombarding the parent material (either Lead, Bismuth or Polonium I'd imagine - I'm not an inorganic chemist or nuclear physicist - edit - its formed by bombarding Bismuth with Alpha particles), with neutrons to produce the element. Even if one could obtain enough of it to make a gram of 2C-A, it would be prohibitively expensive to produce (and would probably cost tens, possibly hundreds of thousands of dollars a gram).

A second point - Astatine is inordinately radioactive - a couple of milligrams of radio-astatine would probably kill you from radiation poisoning. The material would not lose its radioactivity if it was assimilated into the 2C-x molecule.

I hate to say it, but I think someone is pulling your leg with this. I'm afraid this is one phenethylamine that will remain theoretical, and I doubt it would be synthesized any time soon, possibly even within my lifetime.

Source: http://en.wikipedia.org/wiki/Astatine

EDIT: Just read it was an April fools joke...
 
Hmm... Astatine undergoes electron capture, then decaying by positron emission to Polonium.
Another pathway it expels alpha particles then become bismuth....

A 2,5-diMeO-4-metallo- eh? lol
 
what would it be like if all of your 5ht2a receptors had been fried by a highly radioactive 5ht2a agonist? Would you be a zombie? Or would it be like being on olanzapine for 6 months?
 
You'd be dead; because the 5ht2a receptors are in your nervous system and damage from radioactive decay is not exactly "targeted". If you put enough energy into receptor protiens to destry/deform them, cell walls are going to be shredded and water will ionise as well under those conditions (neither of which bodes well for life)
 
And add to that the fact that apparently, enough At to be visible to the naked eye would vaporise itself more or less instantly under the heat released from its own radioactivity.

I'd be very interested to see it attempted though, under external cooling, so the question of its metallicity as an element could be settled.
 
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