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1700mg Lyrica and 600mg of DXM - Trip Report

lyricadragon

Greenlighter
Joined
Jun 19, 2016
Messages
2
Hello all,

This is a short trip report and you will see why very shortly.

For those that do not know Lyrica is a neuropathic pain killer and a drug used to help treat generalized anxiety disorder. It is also a very strong and active drug in the regions on GABA receptors.
It has been described to have an extremely high binding to GABA receptors - thus creating a pathway for abuse.
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TRIP REPORT
T+-60 - 1700mg Lyrica taken one hour before the DXM. As it takes time to kick in.
T+00 - 600mg DXM (Liquid Form)
T+10 - Nothing to much to report - a slight feeling of being drunk. Which I would attribute to the Lyica as this is a common effect.
T+20 - Browsing the internet on the computer and feeling very drunk at this point. However my ability to use the computer is not affected.
T+30 - I pass out.
T+4 hours - I wake up, slumped over the computer desk and in a dazed state. It is midnight at this point and I feel completely intoxicated. I go to bed as I cannot stand up steady.
T+ 12 hours - Wake up with no hangover or after effects.
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Overall - This combination is NOT recommended. DXM has a binding affinity to GABA receptors and this combined with Lyrica which is extremely powerful on GABA was just too much for my brain to handle. At which point I essentially shut down completely. I have never before passed out like this. Going from being completely normal and browsing the internet to being slumped over the desk looking at the last page I cannot remember reading.

BE CAUTIOUS with this combination.

Peace out - Love from Australia.

Tagged by Xorkoth
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No not at all. I am quite used to both the taste and smell of the liquid but also I do not feel sick after consumption.

I suppose in general I have posted this for harm reduction reasons. This combination does not have much internet coverage therefore I thought I might fill the gap.
 
Where are you getting that lyrica binds significantly to GABA receptors, let alone strongly? That is a common misconception, probably because pregabalin has GABA in the name.

DXM does not bind to GABA receptors either, you're quite mistaken.

I am prescribed pregabalin and when I was more sensitive I sometimes took higher doses of it and got a feeling as if catatonically fading into static / white noise - I'm not surprised you passed out that is a huge dose.. Please be careful.

Can't directly think of unsafe interactions between the two, you just took ridiculous doses - the pregabalin most of all and the grand total.
 
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