Benzos 140 mg Diazepam and 550 mg Clozapine

[Michael_25]

I have a high benzo tolerance. But 140 mg will do the trick. However, is it safe to mix with anti-psychotics? Specifically, does it depress my CNS to the point of death?

 

[AlphaMethylPhenyl]

That's an extremely high dose of clozapine. Are you prescribed these medicines at these doses? I would say its not safe, especially given claozapines peripheral gabaergic activity.

 

[Redrawl]

The combination is dangerous. How dangerous is sometimes hard to say, because if you have a high tolerance, it's common that you can use alot more than someone without tolerance.

Nevertheless, it's a dangerous combination, even with tolerance.

(Chronic) benzo users often don't realize how much sedated they allready are, keep that in mind too.