14-methoxymetopon - any1?

[Giza]

Anyone know the potency of 14-methoxymetopon in relation to Morphine?

I read somwhere it was 20,000 times more potent than morphine, then recall reading elsewhere it was only 66 times as potent?? Will somehow help clear this up?

And is 14-methoxymetopon a heavy mu-1 opiod receptor agonist? Mu-1 being the receptor beleived to be responsible for opiate euphoria.

Any and all information anyone has on this compound is greatly appreciated.

 

[Smyth]

Edit: PPOM is the potent one. Methoxymetopon is very similar to OMOM, cept for the xtra methyl group rendering it less addictive.

This is a drug published by Schmidthammer recently (2003). Although it is extremely potent, it is likely that it will never be commonly abused by humans. it is on roughly equipotent with dihydroetorphine, cept it acts on all opiate receptors not just mu. -O-Methyl-Oxymorphone (OMOM) which is 40X oxymorphone in potency is a much more realistic drug. It depends if you are interested in analgesia or veterinary anaesthsiology though.

 

[Giza]

Just looking for the highest mu-1 receptor agonist with minimal respiratory depression and extremely high potency (along par with fentanyl analogs), that would also carry extreme addictive qualities, and a 'high time' of over 1 hour.

Care to provide more information regarding this "PPOM" ?

Or if you know of any other candidates that meet the above criteria dont hesistate to post them. Minimal requirement is at LEAST 1000x the potency of morphine. Preferrably higher. I know such things as Carfenantil have a higher potency than VX nerve gas (wowza), but from what ive read Carfentanil is only 30 minute buzz if even that, which leaves much to be desired.

 

[ebola?]

just wondering...why?
why is this more than an intellectual curiosity?
I mean, unless you're actually running a synth of this...
...
Also, your avatar contains a grammatical error.

ebola

 

[C6H6]

Such potency ratios like 20,000x morphine are often not applicable to humans. For example, etonitazene is said to be 1,000x as potent as morphine. But in a clinical trial, 1mg of etonitazene orally was as effective as 60mg morphine s.c. in suppressing withdrawals in heroin addicts.

The 4'-chloro and 4'-methoxy analogues of etonitazene are listed in the literature as 3x and 100x as potent as morphine. In a clinical trial in surgical patients they were found to be 1/3 and 10x as potent as morphine, respectively.

 

[p-mo]

ROFL when i saw this thread. Give me a bell when u get that island,