Nice idea my man! This can be a place where GL's and BL's can make inquiries as to the safety of certain combinations as well. While we have a potentiation megathread already, maybe we can add a section on that too, in case someone accidentally and unknowingly drinks a cup of WGF juice before their usual deadly cocktail of CNS depressants and dies. In all seriousness though, that might be beneficial.
What I'm interested in (just out of curiosity) is whether a drug like Gabapentin or Lyrica would really be classified as CNS depressants, and if they could really cause an overdose if someone say, took a high dose of gabapentin with their usual dosage of Oxycodone.
I found this:
Which basically says that it exhibits similarities to both stimulants and depressants. The fact that it raises blood pressure, makes me wonder further whether a gabapentin/opiate combo could result in an overdose. I know Lyrica is stronger and I'm pretty sure that it doesn't suffer from the self limiting qualities that Gabapentin does (the reduced bioavailibility at higher dosages), however I'm still curious about that one too.
One dangerous combination that I just thought of also is using methamphetamine/amphetamine in concurrence with asthma inhalers, I'm thinking specifically albuterol sulfate. I know that an overdose of albuterol is possibly by itself and can result in a heart attack, and I can only imagine what adding speed or cocaine could do.