Search results for query: psilocybin

What did it feel like healthwise? Psilocybin, for example, gave me a harsh trip once, but when I came down, I noticed how healthy my body felt. Definitely superior to LSD. Supportive quote: The hangover is what I didn’t like about analogs. Shrooms give you the exact opposite of a hangover...

...to be able to trip to help against my depression. I do want to be able to schedule a time and place for that where I am uninterrupted for that. I think we're still a long way off from legalizing most psychedelics. As far as I know, currently, psilocybin stands the best chance at being legalized.

The study is looking to see if blocking 5HT2A blocks both the trip and the antidepressant effects of psilocybin, with the tripkilling being assumed to be true (based on the study design and how they word things). Seroquel is a really powerful antihistamine, so it combines strong sedative...

Eximia (Psilocybin)

I recall a few months ago, the FDA tested some mushroom chocolate bars and some were found to contain no psilocin/psilocybin, and instead had 4-aco-dmt and a couple kava alkaloids. https://www.cdc.gov/environmental-health-studies/outbreak-investigation-diamond-shruumz-products/index.html While...

Boundary / request: Please don’t invalidate my experience or turn this into a debate about mushrooms. I know psilocybin helps some people—good for you. In my case, it didn’t. After these experiences, my mental health worsened dramatically and stayed that way. I’m not looking for comments like...

Boundary / request: Please don’t invalidate my experience or turn this into a debate about mushrooms. I know psilocybin helps some people—good for you. In my case, it didn’t. After these experiences, my mental health worsened dramatically and stayed that way. I’m not looking for comments like...

Nope. This unfortunately isn't my first time through it, and I've tried and eliminated most other paths through it. Just detoxing straight up and fucking glad for it.

...sea sponges and even 4-ACO-DMT which is a synthetic derivative of Psilocin which is the psychedelic chemical converted by the body from psilocybin which is found in magic mushrooms and truffles. There is a lot of types of DMT out there and a lot of psychedelics for which one is the strongest...

...to find the right thread ask this question figure I’ll ask it here, so I am addicted to kratom, but it really really takes away from psilocybin, so I was thinking if I took a 5 mg oxycodone I might get better benefits be happier because I often forget to re-dose, during the trip and I go onto...

Very interesting and I would double down and agree 👍. On my latest LSD endeavors I was curious as to why I only got ego death when truly seeking it or to be more specific - when the geometric patterns turn translucent and then i am unraveling into another worldly dimension- which i found quite...

Bet they're queuing round the block to be test subjects in that trial... Aye, so you're going to give me the psilocybin now are you? Ok, cool. And now you're going to give me the antidote, right? Ok, just hang on a minute, Im bursting for a piss, I'll be right back. CLIMBS OUT TOILET WINDOW...

Has anyone managed to get a QTest sent to Australia? Or used one? They allegedly measure the exact amount of psilocybin in your mushrooms. Pretty cool if it works but can't find a site that will ship down under.

Hello , I am D. Trismegistus, I also love my Benzos, LSD, DMT, Mescaline, Ketamine, Ganja etc..... I Practice R&D Chemistry and I could use plenty of good anecdotes, I have a wealth of good information. I am 41 yrs. Living on the Oregon Coast and I look forward to talking to you.

Cannabis: impairs memory, makes me lazy. Psychedelics (LSD, psilocybin, DMT): not what I was expecting, lost desire to use them again. Opiods (heroin, kratom): the rush is great, but the nausea is horrible. Methamphetamine: disrupts sleep too much at the doses when it's euphoric. MDMA...

...one resonated with you! And I think you're absolutely right: the stigma often stems from a lack of understanding, not necessarily about psilocybin specifically, but about psychedelics as a whole. For many people, it’s still all lumped together in the “drugs = bad” bucket—regardless of...

...it on the basis that a 5-HT2A antagonist should be capable of antagonizing a 5-HT2A agonist. https://en.wikipedia.org/wiki/Pimavanserin As of November 2024, a phase 2 clinical trial is underway assessing the ability of pimavanserin to block the effects of the serotonergic psychedelic...

Different tool. One is WD-40, the other is a hammer. It's nice to be able to titrate the dose and judge for yourself. Have a sitter or at least lay in the recovery position with high dose exploration.

https://doi.org/10.1016/j.neuron.2025.06.012

4-aco-dmt and 4-ho-met are part of a family of research chemicals which are structurally similar to psilocybin/psilocin (the primary actives in magic mushrooms) and produce similar effects. They fall under a legal grey area in many parts of the world and often appear in the kinds of shroom...