N&PD Moderators: Skorpio Forums Media, Science and Research Neuroscience and Pharmacology Discussion What is the biggest dopamine spike possible without drugs? JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding. You are using an out of date browser. It may not display this or other websites correctly.You should upgrade or use an alternative browser. Members who reacted to message #12 All (1) Haha (1) A Oct 6, 2023 anonymouse77 Bluelighter Messages 528 Reaction score 250 Points 95 Loading… Forums Media, Science and Research Neuroscience and Pharmacology Discussion What is the biggest dopamine spike possible without drugs?