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how to cut 25i-nbome while avoiding hot spots

R

rolodex propaganda

Bluelighter
Joined
Feb 20, 2009
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Since my mg scale cannot accurately weigh out 25i-nbome doses, I want to cut it with creatine so that it is 10% pure and easier to handle and insufflate.

I'm worried about hot spots, parts of powder that are stronger than others. Would dissolving the creatine & nbome in ethanol (or another proper solvent) and letting the solvent evaporate result in an even, homogeneous powder. What solvent would you guys suggest, and what is the pproximate solubility of creatine in it? Any other methods you'd suggest?
 
To echo above, use liquid measurement!

Cutting dry powder is a really bad idea, definitely not a recommended way to prepare a substance for consumption.

(but for informational purposes -- to completely avoid hot spots you would probably need to dissolve both compounds in an appropriate solvent, mix until thoroughly homogenous, and then remove the solvent in a rotary evaporator -- then again, I would be worried about settling that may occur after the homogenized mixture is evaped back to powder).

Also: I would be weary about insufflating bomamines, there is no data concerning that method of consumption.
 
Yeah liquid measurement is easier, but didn't Solipsis have a way where a solution of the compound was dripped onto a pile of mannitol, I think, and allowed to dry?

What do you mean, Roger, there's no data about insufflating NBOMe's? Most of the reports are by insufflation. What data is there on other ROA's?
 
skillet said:
Yeah liquid measurement is easier, but didn't Solipsis have a way where a solution of the compound was dripped onto a pile of mannitol, I think, and allowed to dry?

What do you mean, Roger, there's no data about insufflating NBOMe's? Most of the reports are by insufflation. What data is there on other ROA's?
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i think sublingual is the preferred ROA.
 
perKeceT said:
i think sublingual is the preferred ROA.
Click to expand...

It's quite a common ROA, true, because a lot of people are getting the stuff on blotters. It doesn't sound like a very good one though, many people report fairly mild effects from high doses, and I'd imagine there could be quite a bit of variability in the extent of absorption. I think some more experimenting (eg. adding a surfactant) is needed to make it a really viable ROA.

I'm sticking with plugging, it works really well in my limited (1!) experience, and it's sooo easy.
 
The compound is inactive orally and too potent to insufflate without cutting. I don't want to take it sublingually because it would be too easy to swallow and waste it, plus I prefer the shorter duration of an insufflated trip.

With that being said snorting NBOMEs is common. My question has not been answered. What solvent should I use? Can I just dissolve 50mg 25i-nbome and 450mg creatine in ethanol or acetone and then let it evaporate? Howmuch solvent should I use? Would there be a better dispersant than creatine?
 
Why not plug it, or if you insist on insufflation use liquid measurement?

Anyway, maybe you'd better wait for Solipsis to chime in, or look for the method in the big and dandy 25C-NBOMe thread, I think it was. From what I remember, the compound in a small volume of solvent is added to the solid creatine, so that it only gets slightly damp. The stuff is allowed to dry then mixed thoroughly. I'm still not entirely convinced this is safe.

For solvent you might have to use water, or DCM/chloroform if you have that. Solubility in hot ethanol might be good enough, but I'm not sure it's soluble enough in other solvents to get a high enough concentration. You don't want to make a puddle out of the creatine...
 
I will just leave this here:
Solipsis said:
Today I dissolved 25C-NBOMe in isopropanol (IPA) at 1 mg/ml not for dosing purposes but storage and putting it on a carrier. I took 4 mg of 25C-NBOMe in 4 ml solvent and wet 800 mg of mannitol so that a dose of 300-500 ug will be 60-100 mg including the carrier - for insufflation.
I just put the rest of the 25C in IPA in the freezer, but was just wondering if it would be smarter to evaporate that IPA before putting the material in the freezer.

It probably is but I am not all too worried, it's not that much anyway.

The 25C on mannitol will be dry in a while which makes this one of the most handy methods I can think of.

Mind you I wore a mask and gloves etc and did the procedure in the bathroom (shower), which reminds me I better rinse the shit out of it to be sure before someone goes in there with their naked ass and absorb it somehow.
This is probably really overcautious though.
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Thanks allium, another little snippet here:

Solipsis said:
Paradisum, the way I did it is dissolve a known amount in isopropanol which is a type of alcohol, then added that to a carrier which in my case is mannitol. I am told this is a shitty carrier since it may clog your nose but I calculated an appropriate amount that would be suited to snort. Not an unhandy tiny bit but not a whole lot either. Then I repeatedly mixed it as it dried to get it homogeneous (mixed evenly), and let it dry completely.
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I thought there was a more detailed explanation somewhere, but I can't find it.
 
Would 97% isopropanol work or is 100& required? Would water be a suitable alternative, since creatine and 25i-nbome are both very soluble (i believe) in it?

I've tried weighing out 5mg and dividing from there, and either I cannot accurately divide piles or 1mg yields nothing. How do most people go about insufflating this if they don't cut it?
 
You (or anyone, for that matter) cannot accurately divide a pile by eye.

97% would be fine if the stuff dissolves in it (I have a feeling it might be difficult). Water would also be fine, though it would take longer to dry. I think the key is to dissolve it in a very small amount of solvent so the carrier (creatine in your case) is only moistened when you add the solution to it.

People insufflate it by using liquid measurement or extremely accurate scales.
 
Water is a pain in the ass to evaporate, it has a high specific heat and is very cohesive (thus its hard to "drive off" water molecules from the surface of the liquid because of said cohesion due to intermolecular forces).

I'm not sure, but I would guess 97% IPA would work fine, you can always dry it further with anhydrous MgSO4 (which you can make by dehydrating epsom salts in the oven). Its a bit harder to acquire and more toxic, but methylene chloride would be my first choice of solvent because it evaporates so incredibly fast. That's not a trivial consideration depending upon how much liquid you're trying to evaporate and what equipment you have access to (if working on a really small scale it might matter less).

Honestly though, if both compounds are soluble in IPA that's a good choice and will evaporate fairly quickly.

rolodex propaganda said:
How do most people go about insufflating this if they don't cut it?
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You could have used liquid measurement instead of trying to divide piles (not an accurate method). If you'd dissolved that 5mg in 5ml (or whatever volume) of liquid and mixed it to thorough homogeneity, you could have measured out doses pretty accurately with an oral syringe.
 
rolodex propaganda said:
The compound is inactive orally and too potent to insufflate without cutting. I don't want to take it sublingually because it would be too easy to swallow and waste it, plus I prefer the shorter duration of an insufflated trip.

With that being said snorting NBOMEs is common. My question has not been answered. What solvent should I use? Can I just dissolve 50mg 25i-nbome and 450mg creatine in ethanol or acetone and then let it evaporate? Howmuch solvent should I use? Would there be a better dispersant than creatine?
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Don't try this, it won't work & god knows how much someone will end up doing. The simplest, safest way to go about in suffusing it on a carrier is to simply use liquid measurement & put the liquid on the carrier shortly before you plan on dosing. And this should be done for each individual dose, otherwise there will be hot spots
 
Why not use something that evaporates such as alcohol, measuring it out, and then drying it so you have pure powered form?
 
Roger, I think more water in the IPA might actually increase solubility in this case. And I doubt it's that hard to dry a small pile of moist powder.

Issac, because the quantities are so small, you're likely to lose a significant (and unknown) amount by doing this.
 
If you have an antibacterial agent (shouldn't be too hard to procure), you could simply dissolve in water and put your known dose in a nasal sprayer. Otherwise dissolve in a solvent that is by it's nature antibacterial like ethanol or isopropyl. I would think 95% ethanol should do the trick nicely and evaporate in under a minute. If it requires a lot of solvent simply heat it gently and it will dry out in no time.

Whatever you do, do not cut it with dry powders. And don't cut it with powders dissolved in the solvent either, as Roger&Me pointed out, even a thoroughly mixed solution will dry differently and you will almost certainly end up with spots of cut and others of product.
 
kakti said:
If you have an antibacterial agent (shouldn't be too hard to procure), you could simply dissolve in water and put your known dose in a nasal sprayer. Otherwise dissolve in a solvent that is by it's nature antibacterial like ethanol or isopropyl. I would think 95% ethanol should do the trick nicely and evaporate in under a minute. If it requires a lot of solvent simply heat it gently and it will dry out in no time.

Whatever you do, do not cut it with dry powders. And don't cut it with powders dissolved in the solvent either, as Roger&Me pointed out, even a thoroughly mixed solution will dry differently and you will almost certainly end up with spots of cut and others of product.
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I seriously doubt this last worry. Look if both cut and drug are 100% in solution, then they are going to be evenly distributed. How the hell are a bunch of molecules of drug going to decide to "get back together" again to form clumps in the dried result from the liquid? Molecules in liquid are not "smart" and to not "migrate" towards other molecules like them as it dries... it just does not work like that physically, so I think that is a silly concern. If they are both fully dissolved and the liquid mix shaken up even a little you are going to get a very even distribution in the dried powder, that's just physics. You are being paranoid. Stop smoking so much crack, dude ;)
 
dwayne, as substances fall out of solution and recrystallize, they will preferentially form crystals with others of the same type. so drug and cut will almost definitely precipitate at different times in the evaporation procedure. it's not "just physics", it's definitely "just chemistry" and doesn't always go as first assumed.

Liquid measurement is great if you keep it in liquid form for dosing! but not for evaporation with any degree of homogeneity if you put other substances with it in solution.

For cutting powders, take a hint from the pros and use a coffee grinder. A minute or two and you can be sure of 99.9% (pulled from my ass but probably true) homogeneity. If you doubt me, try homogenizing table salt and table sugar and give me a quantitative analysis of the distribution in various samples of the product :)
 
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