JWH-18 Overdose > Psychosis !!

This is an older thread, I feel like it may get better responses in TDS. TDS mods, feel free to move this to a more appropriate thread, if needed.

B D D - - > T D S
 
Thanks P_C. We will see if any TDS'ers can contribute some value to it here, for the time being. :)
 
The American Association of Psychiatry is now saying that spice can induce extended psychosis and new term psychosis ( psychosis with no previous history ). They have case studies now and there are more and more no doubt to come. I have been regularly monitoring any and all info I can find on these synthetic cannabinoids since I started smoking them over a year ago and just recently there has been a huge influx of negative stories on the web and horror stories of people freaking out and they aren't even smoking it anymore, as well as more doctors and psychiatrists looking at this stuff.
Hopefully scientists will test this stuff more and find out exactly how it fcks somebody up and how to fix us.
Google - spice psychosis psychiatry

Personally I think we all have Dysautonomia from this crap, explains ALL the symptoms and also It's a disease that affects each person uniquely, it has a wide range of symptoms and each person will present one or a combination of them, while being exposed to the same cause of Dysautonomia will affect some people but others will be just fine.
After reading my brains out about my symptoms and about CNS probs, imbalance probs, sounds to me like Dysautonomia fits it to a T and was caused I believe by toxins or by upsetting the balance between the sympathetic nervous system and the parasympathetic nervous system.
 
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The American Association of Psychiatry is now saying that spice can induce extended psychosis and new term psychosis ( psychosis with no previous history ). They have case studies now and there are more and more no doubt to come. I have been regularly monitoring any and all info I can find on these synthetic cannabinoids since I started smoking them over a year ago and just recently there has been a huge influx of negative stories on the web and horror stories of people freaking out and they aren't even smoking it anymore, as well as more doctors and psychiatrists looking at this stuff.
Hopefully scientists will test this stuff more and find out exactly how it fcks somebody up and how to fix us.
Google - spice psychosis psychiatry

Personally I think we all have Dysautonomia from this crap, explains ALL the symptoms and also It's a disease that affects each person uniquely, it has a wide range of symptoms and each person will present one or a combination of them, while being exposed to the same cause of Dysautonomia will affect some people but others will be just fine.
After reading my brains out about my symptoms and about CNS probs, imbalance probs, sounds to me like Dysautonomia fits it to a T and was caused I believe by toxins or by upsetting the balance between the sympathetic nervous system and the parasympathetic nervous system.

So is there a set procedure including therapy and prescription drugs to re- balance the parasympathetic nervous system and the sympathetic nervous system so one can eliminate the symptoms we are experiencing ? My psychologist will not give me a GABA re-uptake inhibitor and is blaming serotonin.
 
I've psychotic like experiences with JWH-XXX. For me it was not quite as severe and did go away fully in a few days. I also took benzo's to calm down the anxiety. (not recommending you toss more chemicals at your brain, just my experience)

I'm wishing you the best, and I hope that like me, you'll feel back to normal with time.
 
I quit smoking this poison 7 days ago, I am almost 100% back to normal in the daytime, anxiety comes on at night but is less intense and of shorter duration, going to the store still gives me an anxiety attack but isn't as intense anymore, basically anything that made me anxious before will set it off, as well as excitement. The first few days it was so bad I couldn't leave the house without freaking out. I credit the GABA supplements I've been taking and exercise for my recovery.

Psychiatrists and doctors know squat about this drug but it's funny that ALL the benzodiazipines work by elevating GABA or its efficacy, and anxiety / panic disorders are connected to low GABA levels, there's ways of elevating GABA without going on these benzos with their horrible side effects and there are fairly strong herbal tranquilizers to help the anxiety in the meantime.

I have posted in the JWH has ruined my life thread with the exact supplements I am taking, it's all about getting the GABA levels back up, this stuff fcked our chemistry and threw the sympathetic nervous system and the parasympathetic nervous system out of balance, basically our sympathetic nervous system is on full bore and the parasympathetic system wich counteracts it and balances it is impaired, this is my theory based on research about these systems, the huge importance of GABA, and how synthetic cannabinoids inhibit GABA greatly because they are full agonists and not partial agonists like THC, MJ also has tons of other cannibanoids in it wich balance it all out as well as cannibidol wich is an anti psychotic ! I think this is why MJ is completely different from this crap and is safe.

Anyways I've listed everything I've been taking on that other thread, hope it helps, the main supplements are L-theanine, B-6, Choline - all for raising GABA, Inositol for seratonin, and for a tranquilizer I am using Valerian wich is actually pretty strong, and Passion Flower to enhance it. I also had some hydrocodone around from when I had a toothache and that REALLY helps with the anxiety. Good luck everybody.
 
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^Thanks for your input about your experience, freak1c...:)

Glad things are improving for you and really hope they continue to do so. Great to have you here on TDS! ;)<3
 
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I'm not even going to read the last pages......

I've been doing synthetische cannabinoids for a damn long minute..... and in my humble opinion; for the OP there was a preexisting anxiety or anxious-state, which was made worse by a JWH or other substance. One use may cause paranoia, but thats extremely short lasting. Many JWH compounds are very short-acting, especially compared to good medical indica or sativa strains, or hash/oil. I've run across none that last longer than my homade hash.
Continued chronic use of any synthetic cannabis is now known to make anxiety problems much worse. It even gets to me sometimes.

But once I stop..... done, in about 3hrs.

Get help, friend. I hardly think it was the JWH that's caused problems... but then again, who really knows what it was you took?

Everyone else.... moderation is key. Smoking up to 3grams of plant material every few days IS a bit much.

<play nice>
 
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Psychiatrists and doctors know squat about this drug but it's funny that ALL the benzodiazipines work by elevating GABA or its efficacy.

No, they, like barbiturates, alcohol and Z drugs, work by binding to GABA receptors as direct receptor agonists, thus acting(more like replacing) like GABA, but not being it, or increasing its amount, or its binding affinity.
 
Same effect, other molecules can bind to the neuron near the GABA binding site and influence GABAs effect, caffiene does this and has an inhibitory effect on GABA, benzodiazepines do this, they increase or imitate GABAs effect, inhibiting nerve transmission.
The American Medical Association just wants to sell you drugs, certainly the fact that people are put on Xanax etc. straight away without even testing a persons GABA levels or trying a treatment to raise GABA with supplements before being put on these benzos with their addiction potential and potentially horrible side effects speaks tomes about how much the medical establishment is either ignorant about it or as I and many others suspect, has tried to suppress research into such matters
from the beginning, and big pharma is not making money off herbs and supplements but is in fact threatened by such things. There are over 40,000 scientific papers published on GABA. Anxiety, panic dosorders, even parkinsons, is related to low GABA levels, why see a shrink that only treats the symptoms and never addresses the cause ? The medical establishment is a crooked business, but alas has always been so. Nueroresearchers such as Eric Braverman understand the huge importance of GABA.
 
Anxiety's a billion dollar business, this is a shizo society, seems the business as usual model is simply replacing anxiety ridden patients with benzo addicted patients.
Or keeping them in inpatient or outpatient therapy and filling em full of drugs until their insurance runs out then see ya. In Los Angeles they literally dump em on the street when this happens, anyone who's been to Santa Monica will certainly see this in a closer way than they probably would like to because that city is absolutely full of homeless mental patients, many who were discharged onto the streets when their insurance ran out. I don't put much faith in the mental health system.
 
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How about an update Drummingfool ? How are you doing ? Still finding GABA supplements helpful ? Me, you, and one other person I'm aware of have been trying the GABA route, 8 days since quitting smoking synth cannabinoids and I'm pretty much back to normal aside from anxiety attacks at the store but they are diminishing in intensity. But if I don't take my supplements I still feel general anxiety and dissociative, not like the first few days but it's still lingering there, but after taking them I feel fine.
 
there was a dude here in rehab that wigg'd out on the shit, he was busted because his eyes were red and went into a panic attack and completely lost it.

the assfuck that busted him (staff) is a jerk anyway..

dunno if the jwh had to do anything with it.. but felt like sharing.
 
All I can say is fuck that shit! I had one cone of K2 and for the next 2 hours I was spiralling out of control, freaking out harder than I ever have on any drug. And I'm a regular pot smoker. The only saving grace for me was that it had a relatively short high.
 
Nueroresearchers such as Eric Braverman understand the huge importance of GABA.
Being the main inhibitory neurotransmitter, it doesn't take a PH.d researcher to see that its rather important, though, so is NMDA, so are the big three sympathetic, dopamine, norepinepherine and serotonin, so is Ach. Raise or drop the levels of ANY of them drastically and generally, some failure mode resulting in death occurs. Play with a little too much, and something unejoyable happens (be it anxiety, seizures, dyskenesias, hyperthermia, psychotic episodes or other eratta problems resulting from CNS regulation being whacked out)

But that wasn't my first point, my first point is exogenous agonist does not equal increasing organic agonist...say for example, exogenous 5HT ligand LSD is not the same as force release of 5HT by MDMA, nor is it the same as serotonin toxidrome. (I think if it had the disseminated vascular coagulation, it wouldn't be as popular as it is.)

exogenous DA antagonist pimozide is a little more severe then lack of DA after an amphetamine binge. (I don't get permanent motor dysfunction from a comedown)

There is a significant difference between the varied exogenous ligands, and the organic one (or depletion of organic one vs blockade by antagonist) the effect is NOT the same, it can be markedly different and very different depending on which synthetic it is. thiopental is just a tad different from gabapentin, wouldn't you say?

and parkinson's re GABA: yeah, it might have some role, but I think the case is pretty solid on parkinson's being primarily DA related.

This wasn't a rant about big pharma or the mental health system, it was about not abstracting two different things into being identical.
 
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^^ what Rangrz said..... he is quite correct.

What I can't wrap my head around is how I can smoke synthetic cannabinoids daily, and all that happens when I smoke to excess is that I get a headache...... exactly the same reaction I get from too much real bud.
But if I take even a 1/2 xanny bar, I'm out cold for 8hrs....... yet others gobble em like mike-&-ikes an can actually walk.

I get edgy sometimes, but only in situations that'd normally put me on it..... and no more than usual.

I've found that its actual problems that cause me anxiety, and not something induced by any one of the many substances I ingest.
 
How about an update Drummingfool ? How are you doing ? Still finding GABA supplements helpful ? Me, you, and one other person I'm aware of have been trying the GABA route, 8 days since quitting smoking synth cannabinoids and I'm pretty much back to normal aside from anxiety attacks at the store but they are diminishing in intensity. But if I don't take my supplements I still feel general anxiety and dissociative, not like the first few days but it's still lingering there, but after taking them I feel fine.

Well, after being on the GABA now for almost 3 months, there's definitely been some changes. My disassociation is almost gone, but a LOT of anxiety still remains... just not all the time. I definitely feel better after taking my GABA, but I only take it at night. There are just certain situations that I know will set me off, and I try to avoid them. For example, there's a specific grocery store that will send me into a panicky state.

I dunno. Like I said, it has definitely helped, that and the fact that I have a new job thats not abusive, but I'm still not 100%. I hope that continuing the GABA treatment will be good. I'll be getting insurance soon, so I'll also be going to a doctor and letting them know whats up.

How about everyone else?
 
All the reports all over about synthetic cannabis makes me think.... how many people were wandering around with undiagnosed preexisting anxiety and such..... and how many people are too willing to jump on the first idea bandwagon as to why they are freaking out.

No drug is safe....... and im getting tired of hearing about kidz with tons of known psych problems on known psych meds, taking these new RCs, freaking out, and then listening to all the bullshit afterwards about it being a particular substance as the cause....

It's not even worth debating the causes/cures for wild JWH-XXX anxiety & paranoia, when theres all kinds of other new cannabinoids being devised daily, each one with an unknown pharmacological profile, and with us having no idea what they are.

For me, yes.... I do experience a little anxiety on this stuff..... but its always transient, and I don't have access to natural THC anymore, so this is the only thing that has the same nausea-killing properties.... otherwise I have to spend big $$ on anti-emetics like ondansetron.
 
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This is my last post on the subject. You all are free to think what you want about this poison but there are some documented facts on this stuff now, for one thing it DOES induce new term psychosis.........pyschosis with no previous history and yes this includes anxiety/ panic disorder. The anxiety is physiological, not mentally induced, this is drastically different than being self conscious around people when you're on pot or nervous/ paranoid and calling that an anxiety attack, also this is different than a mentally induced actual anxiety attack. There are several cases of people having strokes on this crap as well. Anybody who has experienced adverse reactions from this poison such as an extremely high and dangerous heart rate know this comes on without you " thinking " it into being, it is 100% physiological.
I NEVER had any anxiety condition previous to use of this crap, was always highly social and used to very stressing environments and situations, no problem, now after stopping smoking this crap for the first few days I couldn't even leave my freakin house, forget about driving anywhere or going to the store, I was looking into checking myself into a mental hospital because I was a non functioning absolute wreck ALL OF A SUDDEN. Hell my nickname has always been mellow, I am about the mellowest person anybody could ever meet. Luckily I'm okay now but still not 100% and I have read reports about people being off this crap for up to 3 years and they are still a wreck. This stuff changes something, and it's not good. Now you all can maintain your delusions about how great this garbage is all you want just because this hasn't happened to you yet, and I sincerely hope it never fcks you up too, but truth is it DOES wreck a lot of people and saying well this stuff is great I don't know what all these people are talking about they must have some problem I smoke it and I'm just fine la la la la la, that's just being an ass and quite arrogant and doesn't help anybody at all, especially when these sort of posts show up on threads for the casualties so to speak, threads for people having problems from this poison and looking for some answers.
Smoke marijuana it's great, fuck synthetic cannabinoids and fuck the people who make and/ or distribute it, as for the head shops who refuse to distribute it...bravo, as for the head shops that distribute it cause they are making a ton of money...........well that's obviously all they care about, traitors.
 
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