The Big & Dandy Methoxetamine Thread - 4th Dose (don't overdose)

[2charlyecho]

how often were those doses each day spread out by. Im reading a lot of how long it takes to kick in. Did you find this to be a significant factor at all?

They would be spread out by about 2 hours, give or take a bit. Mostly confined to evenings, anything from 6pm to 2am. Deciding when to redose tends to be a problem with MXE, due to the confusionz . It can be hard to tell when you are sober or in the mxe realm sometimes, such is the confusion.

 

[MyExcuse]

I plan to try this soon but I thought it was worth mentioning, as I've noticed this more with MXE than ketamine:

Ketamine produces a simulative effect (marked by a rapid heart-beat), separate from it's DRI action. The following study may prove useful to some of you. I know this especially may attenuate some of the effects I've noticed when in combination with marijuana or re-dosing throughout the night/day.

Also this may help with those of you who feel the need to urinate frequently while on ketamine or MXE.


L-arginine attenuates ketamine-induced increase in renal sympathetic nerve activity.

L-arginine attenuated the ketamine-induced increase in RSNA from 147 +/- 10% to 84 +/- 7%, although D-arginine did not. L-arginine also attenuated the heart rate change from 14 +/- 3 to 0 +/- beats/min. The attenuated responses of RSNA and the heart rate during L-arginine infusion disappeared several minutes after discontinuation of the infusion.

Also, pre-treatment seems to work just as well:

Ketamine did not significantly change RSNA in rabbits pretreated with L-arginine 92 +/- 7% at 2 min. after ketamine.

To add on my theory about combinations involving MXE and cannabis:
Researchers Identify Clues About Marijuana Effects

One such study, "L-NAME, a nitric oxide synthase inhibitor, and WIN 55212-2, a cannabinoid agonist, interact to evoke synergistic hypothermia," published in the February issue of the Journal of Pharmacology and Experimental Therapeutics, reveals how cannabinoids produce one of the drug's most robust actions, hypothermia, or decreased body temperature.

 

[SleepingTaper]

Duration keeps getting shorter and shorter
Break time.

I built my dosages up to 80mg, I was doing it every day until I took 96mg and got super dehydrated (due to an exhausting bike ride earlier in the day (not the MXE) which forced me to quit for nine days, now when I take 40mg it hits me longer & HARDER than ever before. I have also cut my ketamine use down alot, I'm still wondering if there was some cross-tolerance going on.

 

[pharmakos]

I built my dosages up to 80mg, I was doing it every day until I took 96mg and got super dehydrated (due to an exhausting bike ride earlier in the day (not the MXE) which forced me to quit for nine days, now when I take 40mg it hits me longer & HARDER than ever before. I have also cut my ketamine use down alot, I'm still wondering if there was some cross-tolerance going on.

MXE has a major cross tolerance with DXM even, and MXE is a lot less similar to DXM than it is to Ketamine chemically/structurally speaking.

 

[knock]

MXE is a lot less similar to DXM than it is to MXE chemically/structurally speaking.

MXE is identical to MXE.

 

[Ralt]

Planning on IMing 55mg to my thigh tonight. Is the duration of the comeup affected by IMing? Oral and snorted seemed to take two hours.

 

[Albion]

Planning on IMing 55mg to my thigh tonight. Is the duration of the comeup affected by IMing? Oral and snorted seemed to take two hours.

IMing is quite a bit faster than oral and snorting. You'll be pretty gone within minutes.

 

[foolsgold]

damn wish i had some just watch wolf creek and it would of been mad watching that on it . head on a stick lmfao

 

[Mitchi]

Let's get the IM on :D

 

[socalthizzn]

have any other smokers noticed that they are smoking more after taking this stuff its a good month sins i had some and i am smoking 12.5grams in 2 days instead of 3

I always smoke around that much every day or two.
Do you find your thoughts filled with mxe and pot deterrs you from using?



Lol

 

[Desert-Mirage]

i feel strange ha ha ha ha ha ha ah ah ah aha a

 

[socalthizzn]

i feel strange ha ha ha ha ha ha ah ah ah aha a

Play with lights!

 

[BananasAndOranges]

Good stuff. Now that I understand it that is. At first I called bullshit ujntil I had my room spin lol

 

[socalthizzn]

How does mxe react to reagent test kit.

 

[xtcnation]

Mxe tolerance is sky high!!

Been using it just over a month

Starting to consider what this drug is really doing for me, but then again thats what it makes you do. Go over one thought over another

 

[bbx4]

^what doses were you starting at and what type of dosages are you using now?

Just curious. I found my dosages went from 15mg plugged that really fucked me up to about 30mg with 2 weeks daily use to give me that same level. Tolerance rose fast, in about a week. But after that it was pretty constant. Haven't abused mxe for longer than 2 weeks daily though, maybe it rises more...

 

[xtcnation]

started at around 15 to 20mg and now dose around 70mg

 

[Desert-Mirage]

started at around 15 to 20mg and now dose around 70mg

really? i dove straight in with 3 seperate 30mg up the nose periods within 2 hours....and i was like

 

[socalthizzn]

Mxe tolerance is sky high!!

Been using it just over a month

I notice this as well. Duration gets shorter and the effects have become less 'Magical' and 'introspective' and now mainly consist of stimulation & full body numbness with slight stilt legs. It went from being a psychadelic just a stimulating dissociate.

 

[proxopata]

Hi GUYS!


So I've tried MXE two times. First time it was 50mg in bed/darkness but the stuff quality had to be really poor as i didn't feel too much effects and it lasted only for hour or so (insufflated)


NEXT TIME THOUGH WAS SICK! (and really stupid on my side)

So, my and my friends went to a minimal techno party (Troy Pierce vs Heartthrob). Through the course of night 11pm-4pm I ate 2.5 MDMA pills divided into 1 pill and 3 halves in intervals(around 120mgs each) and then when the party was ending i ate another 1.5 at once and went to my friends house to an after party. We drank some booze, and then I had this fiendish idea of taking MXE. My friends were unwilling but in the end ( I know I shouldn't have done this) I managed to convince them (they have never tried any dissociatives before, however, they experienced with psychodelics).

So we did about 50mgs line each (crazy), but after half an hour I didn't feel any effects so I did some more (around 20mgs). And then this MADNESS HAPPENED. I remember lying half naked outside my friends house, trying to talk to my GF but I couldn't say what I wanted to say (really strange feeling), then my friends (some of them were only drunk and baked) decided that I shouldn't talk to her in such a state and took my mobile from me. Then I blacked out and woke up in a different room, with my friends talking to me, and saying they told my GF I was drunk and I would call her in two hours time. I realyl counldt believe them because I thought my GF would be angry as hell, but they told me that se was perfectly fine with me. I felt like in the movie SHUTTER ISLAND. It was so sick. I wasn't sure of ANYTHING .But the time seemed to stop. minutes lasted like hours. Between 8am and 10am seemed like eternity! all my friends reported the same. two of them experienced telepathy (!) It was very intense but still an enjoyable experience. However the experienced lasted unusually long. We did the MXE at 7am and I could still feel the effects at 11am. I know it was stupid to do mxe after an all night rave and having taken about 500mgs of mdma + alcohol + weed. I'm gonna give MXE some more time in the future but will start with lower doses of about 30mgs and what is more important SOBER