• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Benzos Benzos causing irritability

Ashley

Ashley

Bluelight Crew
Joined
Jun 17, 2005
Messages
1,000
Location
NSW, Australia
Has anyone else experienced feeling agitated and irritable after taking benzos? Night before last, my fiance and I picked up 100mg of diazepam and had 50mg each, considering this is a very low dose for us which usually results in no perceptible intoxication, we were pleasantly suprised and delighted that we got quite a nice result. Although, it was short lived and after about 2 hours we just felt generally agitated and irritated as well as being disappointed. Diazepam with its long half life and all should last longer than two hours of enjoyable euphoric effects, surely? Though we could feel as though the Valium was still effecting us because we felt relaxed, though not overly so and slept easily, which is unusual, waking up feeling refreshed, if a bit groggy. Yesterday we acquired 20mg of clonazepam and shared 10mg each which we potentiated with grapefruit juice. Approximately 750mL shared roughly equally between us both while and after consuming the Rivotril. Though we felt the dose, both of us were left unsatisfied yet pretty melow. So I went and purchased another 40mg of clonazepam. We both took 20mg, around 4 hours after the initial 10mg, again shared the same amount of GFJ, but this time we felt absolutely nothing from the second dose which doubled the first. Any idea why? Also, we didn't sleep at all last night. Both of us felt wide awake and like we could do the dishes, if that makes sense. For example, I'm in town collecting my daily dose of Subutex 32mg at 7:30 in the morning. This is very usual to meet to be feeling fine and awake at this hour. Has anyone experienced this lack of sleep/energizing effect from clonazepam? I know most of you don't take such high doses of benzodiazepines so you may find this shocking. Tolerance is a bad thing, as are this class of drugs. Thanks for any input.
 
I was more interested in the irritability and agitation, specifically if anyone had experienced that on high doses or more commonly taken doses. Also, the lack of sleep and energizing effect. Didn't mean to double post. My other thread has received few replies regarding my last few posts. Also, shouldn't double the dosage of clonazepam had an effect? Seeing as the first lot did? Cheers.
 
umm your dosage is absurd.... 20mg klonopin??? i use to dose 3-5mg xanax + 3-5mg klonopin a day 6 months ago, and now im down to taking .25-2mgs klonopin 3-4 times a week, of course i do smoke week, drink, and take lyrica now
 
So, just like the other thread instead of anyone answering my questions I'm just gonna get bashed because of my dosages. I know for a fact others have to take similar dosages after abusing benzos for years. I know its a huge dose of clonazepam, "absurd" I'm not sure, but it is what I AND my partner *need* to get a satisfactory result. I'd probably get picked apart if I listed the dosages we ingest of heroin and methamphetamine too no doubt.. Just forget I ever asked anything.
 
Ashley said:
So, just like the other thread instead of anyone answering my questions I'm just gonna get bashed because of my dosages. I know for a fact others have to take similar dosages after abusing benzos for years. I know its a huge dose of clonazepam, "absurd" I'm not sure, but it is what I AND my partner *need* to get a satisfactory result. I'd probably get picked apart if I listed the dosages we ingest of heroin and methamphetamine too no doubt.. Just forget I ever asked anything.
Click to expand...

Apparently yes, your benzos cause you to be irritable.
 
Ashley said:
Has anyone else experienced feeling agitated and irritable after taking benzos? Night before last, my fiance and I picked up 100mg of diazepam and had 50mg each, considering this is a very low dose for us which usually results in no perceptible intoxication, we were pleasantly suprised and delighted that we got quite a nice result. Although, it was short lived and after about 2 hours we just felt generally agitated and irritated as well as being disappointed. Diazepam with its long half life and all should last longer than two hours of enjoyable euphoric effects, surely? Though we could feel as though the Valium was still effecting us because we felt relaxed, though not overly so and slept easily, which is unusual, waking up feeling refreshed, if a bit groggy. Yesterday we acquired 20mg of clonazepam and shared 10mg each which we potentiated with grapefruit juice. Approximately 750mL shared roughly equally between us both while and after consuming the Rivotril. Though we felt the dose, both of us were left unsatisfied yet pretty melow. So I went and purchased another 40mg of clonazepam. We both took 20mg, around 4 hours after the initial 10mg, again shared the same amount of GFJ, but this time we felt absolutely nothing from the second dose which doubled the first. Any idea why? Also, we didn't sleep at all last night. Both of us felt wide awake and like we could do the dishes, if that makes sense. For example, I'm in town collecting my daily dose of Subutex 32mg at 7:30 in the morning. This is very usual to meet to be feeling fine and awake at this hour. Has anyone experienced this lack of sleep/energizing effect from clonazepam? I know most of you don't take such high doses of benzodiazepines so you may find this shocking. Tolerance is a bad thing, as are this class of drugs. Thanks for any input.
Click to expand...

If you are taking these amounts of meds you should join a NA meeting, and I mean this in a caring way. Long-term this will just do you no good and you need to work on lowering the dosage and frequency. Do yourself a favour and try to give yourself a break. At these large doses anything can happen over time. irritability is not even worth mentionning compared to other brain disorders that can eventuate. Take care dude and please just visit a couple of NA meeting-the people are quite awesome there.
 
Uh, can you guys address the question instead of bashing the poster?

That might help more....

Yes, irritability and other paradoxical reactions are not that unusual with benzos, particularly in large doses. There are a number of other reports of such effects on bluelight and erowid. Keep in mind that although you feel energized, you are probably more impaired than you realize.

Those doses are particularly high; i don't think I can recall reading any reports of people taking 30mg of clonazepam within a day.

You might be at the point where you're not going to get a good high from benzos until you take a long break. Many others with large benzo habits have reported reaching a point where no dose of benzos will produce a decent high. It sounds like that's where you are, unfortunately.
 
Last edited:
the reason you're feeling irritable even though seems contradictory to the purpose of a benzo is because of dosages and you've been taking it too long. we're not bashing you but basically youre getting that benzo high (or to make you feel normal) when you take some, then there is a huge slump. taking benzos (at least short term and low dosages) shouldn't do that at all.

I had like a 3 week bender with benzos (due to exams), I just cut it all off i experienced about 4-5 days of withdrawals (tremors and such) then it went away. mind you if you been taking it over a month i wouldnt just go cold turkey. I was doing about 20-30mg valium, 6mg xanax and clonazepam not that much I found 1mg tops to be extremely beneficial (prob cause due to long half life).
 
This thread was made 3 years ago.

I don't think he's still feeling irritable... then again maybe he is. Who knows eh?
 
^ This thread was made 3 years ago, but I would like to point out that the agitation in this case wasn't caused by the diazepam itself. Rather, the effects simply wore off, leaving them with rebound anxiety/irritability.

People don't seem to understand, in spite of diazepam's long half life, it has a VERY SHORT duration of action, 1.5-3h with acute use.

High doses of benzodiazepines can certainly cause paradoxical effects, though.
 
Lorne??? said:
^ This thread was made 3 years ago, but I would like to point out that the agitation in this case wasn't caused by the diazepam itself. Rather, the effects simply wore off, leaving them with rebound anxiety/irritability.

People don't seem to understand, in spite of diazepam's long half life, it has a VERY SHORT duration of action, 1.5-3h with acute use.

High doses of benzodiazepines can certainly cause paradoxical effects, though.
Click to expand...

I briefly spoke about half life v duration of action with my Pscyh via email and he confirmed it and said it was one of the most common misconceptions for both users and clinicians... yet I can hardly find anything about it on the web? Do you have any sources that I can read up on?
 
Of course I do Rybee! Give me a minute...

(Btw, I think it was the case for this poster, because they immediately said "we felt good for 2 hours and then got irritated"...

IBut I'll post something, just a moment.
 
http://www.ccjm.org/content/57/Supplement/S-6.full.pdf

They're is an interesting paper, which explains why duration of action a T1/2 are not mutually exclusive for the benzo's. It also provides some nice data about 4 of the most common benzos(diazepam, lorazepam, nitrazepam, and my fave, clonazepam.) including they're lipid solubility and binding affinity(and only 3 pages, so not too much to read)

(Well I wanted to post this particular paper, but I had to dig it out again!
 
And here's a nice table, comparing the many benzo's, which includes both the duration of action, and half life of each, listed seperately.

http://www.thecarlatreport.com/sites/default/files/2011%20TCPR%20Benzo%20Table.pdf

(Edit: actually, looking at that chart, a lot of the information is just plain wrong, but, I guess I'll leave it, since it illustrates the point that it is widely accepted that benzo's have a differing duration vs half-life. FTW, clonazepam and lorazepam actually last the longest)
 
Last edited:
I once had a big bet in football so I took several footballs of xanax to calm me down.......needless to say, it caused me to be irritable ........I think with benzos, less is better.

I don't have a tolerance to benzos & 2.5mgs of Valium is really nice & takes out any irratible feeling from opiates or if I'm just stressing out.

Valium to meet is a ton better to chill out on & take away a stressful day but don't make a habit of any benzo because they are vicious to get off of when you're hooked.
 
You must log in or register to reply here.
Top