(a) CANNABIMIMETIC AGENTS.—Schedule I, as set
4 forth in section 202(c) of the Controlled Substances Act
5 (21 U.S.C. 812(c)) is amended by adding at the end the
6 following:
7 ‘‘(d)(1) Unless specifically exempted or unless listed
8 in another schedule, any material, compound, mixture, or
9 preparation which contains any quantity of
10 cannabimimetic agents, or which contains their salts, iso11
mers, and salts of isomers whenever the existence of such
12 salts, isomers, and salts of isomers is possible within the
13 specific chemical designation.
14 ‘‘(2) In paragraph (1), the term ‘cannabimimetic
15 agents’—
16 ‘‘(A) means any substance that is a cannabinoid
17 receptor type 1 (CB1 receptor) agonist as dem18
onstrated by binding studies and functional assays
19 within the following structural classes:
20 ‘‘(i) 2-(3-hydroxycyclohexyl)phenol with
21 substitution at the 5-position of the phenolic
22 ring by alkyl or alkenyl, whether or not sub23
stituted on the cyclohexyl ring to any extent.
24 ‘‘(ii) 3-(1-naphthoyl)indole or 3-(1-
25 naphthyl)indole by substitution at the nitrogen
26 atom of the indole ring, whether or not further
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1 substituted on the indole ring to any extent,
2 whether or not substituted on the naphthoyl or
3 naphthyl ring to any extent.
4 ‘‘(iii) 3-(1-naphthoyl)pyrrole by substi5
tution at the nitrogen atom of the pyrrole ring,
6 whether or not further substituted in the indole
7 ring to any extent, whether or not substituted
8 on the naphthoyl ring to any extent.
9 ‘‘(iv) 1-(1-naphthylmethyl)indene by substi10
tution of the 3-position of the indene ring,
11 whether or not further substituted in the indene
12 ring to any extent, whether or not substituted
13 on the naphthyl ring to any extent.
14 ‘‘(v) 3-phenylacetylindole or 3-
15 benzoylindole by substitution at the nitrogen
16 atom of the indole ring, whether or not further
17 substituted in the indole ring to any extent,
18 whether or not substituted on the phenyl ring
19 to any extent.; and
20 ‘‘(B) includes—
21 ‘‘(i) 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-
22 hydroxycyclohexyl]-phenol (CP-47,497);
23 ‘‘(ii) 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-
24 hydroxycyclohexyl]-phenol (cannabicyclohexanol
25 or CP-47,497 C8-homolog);
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1 ‘‘(iii) 1-pentyl-3-(1-naphthoyl)indole
2 (JWH-018 and AM678);
3 ‘‘(iv) 1-butyl-3-(1-naphthoyl)indole (JWH-
4 073);
5 ‘‘(v) 1-hexyl-3-(1-naphthoyl)indole (JWH-
6 019);
7 ‘‘(vi) 1-[2-(4-morpholinyl)ethyl]-3-(1-naph8
thoyl)indole (JWH-200);
9 ‘‘(vii) 1-pentyl-3-(2-
10 methoxyphenylacetyl)indole (JWH-250);
11 ‘‘(viii) 1-pentyl-3-[1-(4-
12 methoxynaphthoyl)]indole (JWH-081);
13 ‘‘(ix) 1-pentyl-3-(4-methyl-1-naph14
thoyl)indole (JWH-122);
15 ‘‘(x) 1-pentyl-3-(4-chloro-1-naph16
thoyl)indole (JWH-398);
17 ‘‘(xi) 1-(5-fluoropentyl)-3-(1-naph18
thoyl)indole (AM2201);
19 ‘‘(xii) 1-(5-fluoropentyl)-3-(2-
20 iodobenzoyl)indole (AM694);
21 ‘‘(xiii) 1-pentyl-3-[(4-methoxy)-ben22
zoyl]indole (SR-19 and RCS-4);
23 ‘‘(xiv) 1-cyclohexylethyl-3-(2-
24 methoxyphenylacetyl)indole (SR-18 and RCS-
25 8); and
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1 ‘‘(xv) 1-pentyl-3-(2-
2 chlorophenylacetyl)indole (JWH-203).’’.