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The Big & Dandy Methoxetamine Thread - 2nd Dissociation

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I don't really get it?

What is wrong with names like Methoxetamine, Mephedrone ect ect?

Why does it need to have some retarded "street name"..?

Because Methoxetamine and Mephedrone are street names to an extent.

MXE= 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone
Mephedrone=(RS)-2-methylamino-1-(4-methylphenyl)propan-1-one
 
Methoxetamine is an okay name, just stick to that. Mephedrone sounds too much like methedrone and methadone and shit so that is very unfortunate and moronic but okay since ephedrone is another name for methcathinone adding the extra M for an extra methyl is after all appropriate.

The retarded street names that disgust me and which I take it Mr Toad means are those that are trying to advertise themselves like 'white rush' or 'rhino xtc', no idea what the hell al these vendors are talking about - they are chemicals so use chemical names. Forget the toy names because they are not meant to be used as such.
Which is the same reason I think these '... flip' combo names are pubescent. You are not cool if you mix a stupid amount of drugs, call it a "heroic dose", coin a term that ends with flip and hope the term catches on confirming yet another time that you are a hero.

People like that should really rethink their attitude! Yes I have done the Fear & Loathing gig where I tried psychedelics in inappropriate settings to mindfuck myself. It's a phase and I am over it. But I never pretended we are talking about Pokemon or something.

ok /rant

Saw a vendor site that listed the active dose at 0.15 g *double facepalm*, contacted him after which it was corrected. Seriously if these guys don't understand decimal positions why do we trust them to put an as good as unresearched drug in the mail for us. No wonder people report to get the wrong stuff or wrong amounts.

Gah! sometimes I just need to panic a little about what the fuck is going on. As far as I could tell things weren't so irresponsible before mephedrone and MDPV and some other shit got thrown on the market. Around that time things got significantly worse.
 
Short answer is that I don't know. But having said that I would maybe recommend caution. There have been a number of reports of very uncomfortable experiences combining this with certain serotonergics - symptoms experienced sound suspiciously like a mild case of Serotonin Syndrome. And even a mild case of that is far from mild really.

I have no clue what the possible mechanism for causing such symptoms would be or why it only seems to be with certain serotonergics (MDAI, Methylone and 6-APB seem to be the main culprits that I've seen, with MDMA getting fairly mixed reviews but no out and out horror stories like the above). Especially odd when reports of combining with aMT have all been extremely positive. It's very strange but there have been enough warning about combos with the above to make me think there really is some kind of issue with certain serotonergics. At least in some people. Don't recall seeing many (any?) good reports of combining with the three above from anyone so far though.

Prozac is obviously not on the list and don't recall it coming up before. Just the fact that there seems to be a possible problem in the serotoninny arena would make me cautious combining them - I'd suggest starting at a very low-dose to test the waters and go up gradually initially. Having said that, I have no problems combining with my daily tramadol dose. It's an SNRI rather than an SSRI but I imagine there to be some similarities. Perhaps.

Thanks for the response, I think I'll just make sure she's totally aware that she's entering uncharted territory to some extent and start very very low and see what happens. I'll be sure to share my findings as well! Not to suggest they'll mean anything on their own, but every report is closer to a piece of knowledge!
 
Having just finished with my second bag of Methoxetamine, I have a few observations.

Best recreational use: low dose insufflation.
Best entheogenic use: high dose rectal

Side effects noticed:
1) Some stomach discomfort after prolonged use
2) Noticeably increased tolerance to dissociatives

Addiction Potential:
My take: High; I like this substance a lot, and do not have reservations about repeatedly redoing, of taking it often.
My friends take: The substance seems to have a mild anti-addictive mechanism. High doses reduce the desire to dose again in the future.

Best combinations I have taken:
1) 180mg methoxetamine sublingual + 45 4-AcO-DMT oral + 30mg methoxetamine nasal
2) 80mg methoxetamine nasal + 35mg 4HO-MPT vaporized
3) 100mg methoxetamine rectal + 18mg 2C-I oral + 90mg DPT nasal
4) 100mg methoxetamine sublingual + 200mg MDMA rectal + 40mg Methoxetamine nasal
5) 180mg methoxetamine rectal + 30mg 2C-I rectal (combo was overstimulating)
 
Caution about 5HT Substrates and MXE

JS Pete describes the exact same "Hyper-Lucid" or "Third-Eye" state that i got from combining Methylone and MXE. And JS-Pete's MDMA session was a hole day away by then. I have to admid that this state is extremely seductive (i didn't really wanted to tell it before), it's like standing on top of the Maya Pyramid and being permeated by sheer golden light. But the suspicion of hard-core happy neuron-frying that was going on badly had ultimatively grab me 8 fucking mg of Clonazepam. Maybe a panic reaction, but how could one really panic while being God. Damn, guys we are witnessing something big here, maybe an upcoming drug revolution. So, lets hold our grip and ever repeat the two magical words: Harm Reduction, for god sake!!!


Short answer is that I don't know. But having said that I would maybe recommend caution. There have been a number of reports of very uncomfortable experiences combining this with certain serotonergics - symptoms experienced sound suspiciously like a mild case of Serotonin Syndrome. And even a mild case of that is far from mild really.

I have no clue what the possible mechanism for causing such symptoms would be or why it only seems to be with certain serotonergics (MDAI, Methylone and 6-APB seem to be the main culprits that I've seen, with MDMA getting fairly mixed reviews but no out and out horror stories like the above). Especially odd when reports of combining with aMT have all been extremely positive. It's very strange but there have been enough warning about combos with the above to make me think there really is some kind of issue with certain serotonergics. At least in some people. Don't recall seeing many (any?) good reports of combining with the three above from anyone so far though.

Prozac is obviously not on the list and don't recall it coming up before. Just the fact that there seems to be a possible problem in the serotoninny arena would make me cautious combining them - I'd suggest starting at a very low-dose to test the waters and go up gradually initially. Having said that, I have no problems combining with my daily tramadol dose. It's an SNRI rather than an SSRI but I imagine there to be some similarities. Perhaps.
 
This month's (March 2011) Dazed & Confused MAgazine in the UK has a feature on research chemicals. The journalist tries out MXE and talks to a user of it. Painted in a very harm reductive tone and well done I thought.


'DRUGS: RESEARCH CHEMICALS
A hands-on investigation into the world of 'psychonauts', as our man risks ego death and psychological catastrophe in his attempt to understand those who act as guinea pigs for newly synthesized chemical compound.'
 
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JS Pete describes the exact same "Hyper-Lucid" or "Third-Eye" state that i got from combining Methylone and MXE. And JS-Pete's MDMA session was a hole day away by then. I have to admid that this state is extremely seductive (i didn't really wanted to tell it before), it's like standing on top of the Maya Pyramid and being permeated by sheer golden light. But the suspicion of hard-core happy neuron-frying that was going on badly had ultimatively grab me 8 fucking mg of Clonazepam. Maybe a panic reaction, but how could one really panic while being God. Damn, guys we are witnessing something big here, maybe an upcoming drug revolution. So, lets hold our grip and ever repeat the two magical words: Harm Reduction, for god sake!!!

Liking that unintentional pun :P A 'hole' day away haha.

I had taken a lot of MDMA though, was definitely still high those 24 hours later. Also I am a great sufferer of brain zaps. I get them after even light use of serotoninny drugs, and after heavy use I suspect my zaps are as violent as they come. Proper defibrillatory seizures. Interestingly MXE stops them. A godsend when I am trying to get to sleep.

Also much love for the MXE god/meaning of life/rebirth experiences <3
 
Methoxetamine - working on its similarity to ketamine - is likely to be an NMDA antagonist (the dissociative aspect) and a dopemine reuptake inhibitor (the longer-lasting, stimulating aspect).

However, UNLIKE ketamine, it appears to be a weaker NMDA antagonist but a MUCH more potent DRI. It's this aspect which is a cause for concern as far as I'm concerned; the potential for dangerously high acute hypertension is a big risk here (ketamine's use in adults is advised against even as a relatively weak DRI for this reason, a nurse friend tells me).

Therefore, I think we need to try and make sure that people are aware of the possible risks of combining with potent dopaminergic drugs, eg amphetamines, meth, meph(?), mdma (less risky I'd imagine compared to these others though), and - really going out on a limb as I'm an armchair drug scholar - SSRIs, going on the assumption that serotonergic action can also raise blood pressure...?

All imvho, and none of this should be taken as rote without your own research, of course =o)

/dm
 
I have tried methoxetamine four times since I finally received, it is excellent but it is absolutely stimulating as hell for a long time at high doses. With just ~30mg, I can sleep within four or five hours after though.
 
the only sad person at bass center2

can't if tellguyweallknow is being sarcastic or serious. but if the latter, it's the attitude that's messed messed up not mxe.

yes indeed theres absolutly NOTHING wrong with mxe but in my case it was my bad choices in handeling and set and setting that i think will keep me from ever enjoying dissociatives again, i guess thats the price i have to pay for being stupid with them. just feeling the effects will remind mt for how i fucked up a once in a life time chance to have the time of my life in a amazing show that will never repeat itself and how after investing SO much time and SOOO much energy on only 1 girl, she gave me plenty of chances to say/do the right thing, she gave me the most passionate hug i have ever gotten and we were grinding and even kissed alittle bit but even through with her giving me so many chances to get it right my stupid my high ass aparently fucked up on most of them and she booked as soon as the show ended. i even asked her at some point if she wanted to go to the after party with me when it ended she indicated she had to go make a phone call and disappered...never to be seen again. i didnt even enjoy half the show becuase i was already extremely exhausted but forced my self to keep dancing just to keep up with her, but later found all my sacrifice was for absolutly nothing. :(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:( so is mxe a bad drug?no. but i think my history with it will always keep me from enjoying dissociatives, or even being extremely high on anything for that matter...untill now i felt like i was missing out by being sober but after that day i feel like im missing out by being too high---which i know is a good thing but i feel incredicly empty and pointless for fucking up my one in a life time bassnectar concert and being uncapable of making friends to hang with after the show. i wish i could go back in time.
 
Yeah, maybe a new name is in order...I'm confused...METHOXETAMINE blablabla

MXE? MKET?

MXE works well for a street name. I tend to be a fan of giving RCs street names when talking about them in real life. I agree it's annoying when people some on here and use retarded names, but saying "methoxetamine" in a conversation 20 times gets a little old. Stuff like 5-meO-DALT is even worse for that. My friends and I came up with the name "modalt" for that one and it makes it much easier to talk about. Typing it is fine, but saying "Five em e oh dee a el tee" is a bit of a tongue twister.
 
yes indeed theres absolutly NOTHING wrong with mxe but in my case it was my bad choices in handeling and set and setting that i think will keep me from ever enjoying dissociatives again, i guess thats the price i have to pay for being stupid with them. just feeling the effects will remind mt for how i fucked up a once in a life time chance to have the time of my life in a amazing show that will never repeat itself and how after investing SO much time and SOOO much energy on only 1 girl, she gave me plenty of chances to say/do the right thing, she gave me the most passionate hug i have ever gotten and we were grinding and even kissed alittle bit but even through with her giving me so many chances to get it right my stupid my high ass aparently fucked up on most of them and she booked as soon as the show ended. i even asked her at some point if she wanted to go to the after party with me when it ended she indicated she had to go make a phone call and disappered...never to be seen again. i didnt even enjoy half the show becuase i was already extremely exhausted but forced my self to keep dancing just to keep up with her, but later found all my sacrifice was for absolutly nothing. :(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:( so is mxe a bad drug?no. but i think my history with it will always keep me from enjoying dissociatives, or even being extremely high on anything for that matter...untill now i felt like i was missing out by being sober but after that day i feel like im missing out by being too high---which i know is a good thing but i feel incredicly empty and pointless for fucking up my one in a life time bassnectar concert and being uncapable of making friends to hang with after the show. i wish i could go back in time.

What the the fuck have this to do with MXE? Keep your personal dramas out of this thread.
 
yes indeed theres absolutly NOTHING wrong with mxe but in my case it was my bad choices in handeling and set and setting that i think will keep me from ever enjoying dissociatives again, i guess thats the price i have to pay for being stupid with them. just feeling the effects will remind mt for how i fucked up a once in a life time chance to have the time of my life in a amazing show that will never repeat itself and how after investing SO much time and SOOO much energy on only 1 girl, she gave me plenty of chances to say/do the right thing, she gave me the most passionate hug i have ever gotten and we were grinding and even kissed alittle bit but even through with her giving me so many chances to get it right my stupid my high ass aparently fucked up on most of them and she booked as soon as the show ended. i even asked her at some point if she wanted to go to the after party with me when it ended she indicated she had to go make a phone call and disappered...never to be seen again. i didnt even enjoy half the show becuase i was already extremely exhausted but forced my self to keep dancing just to keep up with her, but later found all my sacrifice was for absolutly nothing. :(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:(:( so is mxe a bad drug?no. but i think my history with it will always keep me from enjoying dissociatives, or even being extremely high on anything for that matter...untill now i felt like i was missing out by being sober but after that day i feel like im missing out by being too high---which i know is a good thing but i feel incredicly empty and pointless for fucking up my one in a life time bassnectar concert and being uncapable of making friends to hang with after the show. i wish i could go back in time.

Dude, if I understand this right, you just met a random girl at a concert. There are plenty more of them. Life goes on.
 
^ Yeah, your life must be shit if you act like that every time you don't bring a girl home from a concert unless you don't go to many or got some pretty mad skills. (Also assuming that you are not one of the performers of said event :) )
 
The most important question about this drug has not yet been answered - how on earth do you pronounce it?

I'm assuming the "-xetamine" part rhymes with "ketamine", so phonetically "zetamine".

But what about the first part? "Metho" as in "method", or "Meh - tho" with the second syllable rhyming with "drop", or is it "mee-tho"?

This is keeping me awake at night and making it difficult for me to sustain an erection.
 
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