As mentioned in this thread,
One big problem we're having is that a lot of the smarter members here have been apparently providing free consulting work to marginally (or completely) illegal companies who would like to make lots of research chemicals to sell to people to get high on. And, basically, if a pharmaceutical company were to ask the same things of us, they would also give us thousands or tens of thousands of dollars while introducing new drugs to the public (with probably horrible side effects). This is multiplied by the fact that these drugs tend to create more health problems than the solve, compared to real pharmaceuticals.
I don't know if there's an easy answer to this aside from sticking to low abuse drug class discussions like psychedelics and... er, psychedelics, and otherwise harm reduction. Meanwhile, less well informed people have been flooding the forum with generally terrible ideas of new drugs to make, which is also a bad thing if companies start to pick up on those.
Not sure there's an easy answer to fixing this!