I think most opiates retard ejaculation/ orgasm in both males and females.
To be honest (and graphic) I can come on tramadol but on Morphine or Opana, etc...
It depends largely on your tolerance, etc...
There is a Sex & Relationship Forum, but I think this goes better here.
If you are in for a one-nighter or a short fling, it helps to take your last dose (depending on half-life_ about 6-12 hours before you are expecting to have sex. So in this case it's a downside I suppose.
However, For someone like me who is in a long-term committed and loving relationship, It's not so bad. I obviously take pleasure in making my fiance happy, and when I am on suboxone (my current script) it is impossible to finish, but I can stay hard for hours and hours. This is great because:
1. In a monogamous relationship it is nice to not have to use condoms (IF you know that you won't finish)... which leads to #2
2. Birth Control for women is often harmful to long-term health, Bp, heart rhythm, etc... As a long-term committed partner I don't want my future wife taking anything harmful to her health. (check out the YAZ thing that caused several deaths)
3. When you are good to go, you will KNOW within 2-3 minutes of starting whether or not you will finish, so IF you are in a monogamous relationship you can wear a condom.
4. When you are making your girl EXTREMELY happy, you will feel awesome, she will love you even more.
5. It is an incentive to establish a loving, trusting, long-term monogamous relationship which really truly does help greatly with addiction/ habituation, and even people on Pain Management as less anxiety, and more seratonin and buprion, can really lessen the pain signals being sent to your brain as mental pain can often be related to physical pain.
This is just my opinion and best of luck.
P.S. I hope that this thread title could be changed for easier searching, and maybe be added to the OD "Threads of Importance" list as it is a very important part of both physical and psychological health, which have much to do both with pain response and addiction and habituation to opiates.
I cannot comment on amphetamines, or barbiturates, but I'm sure someone will be able to.
As far as LSD and MDMA/MDA are concerned it can be a very enlightening and bonding experience for you and your partner. I wouldn't recommend it with any random person though as you will have some type of bad trip, or end up way attached to them in the morning and a month down the line realize it should have just been a one night stand.
Best of luck, I hope this becomes an important thread in OD as it is an important issue for both males and females, addicts, chippers. pain patients, and anyone else who experiments with serious drugs.