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  • BDD Moderators: Keif’ Richards

Codeine / Tramadol Booster

B

benzofan

Greenlighter
Joined
Jul 23, 2010
Messages
337
I know that ATARAX (hydroxyzine, a weak antihistamine) can potentiate TRAMADOL (for sure)

Do you know the best substance to mix with codeine to have a good buzz ?

(because as you probably know, we cannot take too much codeine --> over 700 mg it is dangerous for the liver)

Of course , I don't have stronger opiates :X If yes my question would be stupid, I'm waiting on hydrocodone but I cannot wait anymore (it will be here in 20 days it is too long... ;) )

Need to find a solution with my poor codeine (and /or tramadol)

But over only 400mg tramadol (in one go) it is also dangerous, even it is not a strong opioid...

quetiapine (SEROQUEL at low dose = 25 mg) (strong anti histamine compare to ATARAX) + TRAMADOL maybe ?

Is it a good idea to maybe mix codeine and tramadol together ? (it is maybe strange, but I never tried that)

I mean e.g. : 200 mg Tram + 300 mg codeine, is it maybe better than 500 mg codeine alone ?

Just an example please give me your experiences and knowledge

THANKS !


I know, I try to find the magic solution : how to have a strong opiate (yes, I mean medium strong, I don't ask the impossible) with a mixture of weak opiates and other things like anti psychotics... %)
 
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DUDE,

SEROQUEL is an H1 histamine receptor antagonist. Seroquel blockades only H1 (histamine) at low doses; it then hits a couple other receptors, and at high doses (well into the triple-digit milligrams) it finally begins to blockade D2, which gives you the antipsychotic effect. At very low doses (<25 mg), quetiapine acts primarily as a histamine receptor blocker (antihistamine) and α1-adrenergic blocker. After 50 mg seroquel binds more and more serotonin receptors and at high doses (over 200 mg) seroquel starts blocking significant amounts of dopamine receptors.
(normally I post these things in a advanced drug discussion but it is not my goal here)

and yes it is a famous anti-psychotic

But anyway thanks
 
Yes, but it is labeled an "atypical anti-psychotic". Those are just some of the effects produced from Seroquel.

Seroquel is a horrible drug to take with opiates, it'll just knock you out or make you feel shitty. It doesn't act like an anti-histamine, even if it does have action at the histamine receptors.
 
K'd-OUT-in-AZ said:
Yes, but it is labeled an "atypical anti-psychotic". Those are just some of the effects produced from Seroquel.

Seroquel is a horrible drug to take with opiates, it'll just knock you out or make you feel shitty. It doesn't act like an anti-histamine, even if it does have action at the histamine receptors.
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OK thanks ! but do you really know something wich can boost codeine ? that's the point (maybe nothing exists :? )
 
tonic water is said to boost codeine nicely, pomegranate juice might it's unclear though. if you have some weed then maybe have a bowl that always does the trick, though I do realize that some people are unable to do so for whatever reason. promethazine is another that supposedly works well( i havn't tried it).


HR- a good course of action in the long run would be to take a half a day to a day off from the codeine and let your tolerance bounce down for codeine and wean off the tram over a week or two. then use lower doses of codeine with Dextromethorphan to keep tolerance stable. This way you can enjoy using opiates without tolerance rising to quickly. dextromethorphan and tram can't be used together due to the danger of serotonin syndrome i believe.
 
OK thanks ! but do you really know something wich can boost codeine ? that's the point (maybe nothing exists )
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You need to remember that Codeine is a prodrug so anything you do to enhance your liver function to get more active metabolites is also going to remove the actives faster. Same deal with Tramadol to demethyltramadol or whatever I think but it may be active on its own.

(because as you probably know, we cannot take too much codeine --> over 700 mg it is dangerous for the liver)
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Ummm I don't know that. There is a theoretical ceiling dose where no more of the drug can be processed to morphine and C6G or whatever. Same with Tramadol I guess but you wouldn't get that high without seizure threshold issue first.

The only way you are going to be able to get "the most" out of a high with Codeine or Tramadol (think of them as basically the same) is in synergy with other drugs like booze or whatever else you aren't supposed to take. Or as was said Promethazine which will make you nice and sleepy.
 
amapola said:
You need to remember that Codeine is a prodrug so anything you do to enhance your liver function to get more active metabolites is also going to remove the actives faster. Same deal with Tramadol to demethyltramadol or whatever I think but it may be active on its own.


Ummm I don't know that. There is a theoretical ceiling dose where no more of the drug can be processed to morphine and C6G or whatever. Same with Tramadol I guess but you wouldn't get that high without seizure threshold issue first.

The only way you are going to be able to get "the most" out of a high with Codeine or Tramadol (think of them as basically the same) is in synergy with other drugs like booze or whatever else you aren't supposed to take. Or as was said Promethazine which will make you nice and sleepy.
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FOR SURE IT IS A FACT NEVER GO UP TO 700-800mg codeine !!! it is dangerous
don't play with that

2) Dose over 300mg codeine will change nothing in terms of effect (not really noticeable) then take 800mg codeine is completely stupid (and dangerous)

more dangerous than take a reasonable dose of hard opiate

Take 50mg of hydrocodone you will have a nice buzz and you don't kill your liver

For tramadol the limit is 400mg (In one go) if you want to go higher take Klonopin to avoid seizure but again it is completely stupid, a small dose of hard opiate is much more better.

That's the reason I always want take a "standard" dose of a weak opiate if I have no hard opiate and just would like to know if a "magic" substance can boost safely the weak opiate. Apparently the answer is NO. or maybe the tonic water =D=D=D=D=D the most funny thing I ever heard !
 
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K'd-OUT-in-AZ said:
Yes, but it is labeled an "atypical anti-psychotic". Those are just some of the effects produced from Seroquel.

Seroquel is a horrible drug to take with opiates, it'll just knock you out or make you feel shitty. It doesn't act like an anti-histamine, even if it does have action at the histamine receptors.
Click to expand...

anyway FYI it is a strong antihistamine
 
benzofan said:
FOR SURE IT IS A FACT NEVER GO UP TO 700-800mg codeine !!! it is dangerous
don't play with that

2) Dose over 300mg codeine will change nothing in terms of effect (not really noticeable) then take 800mg codeine is completely stupid (and dangerous)

more dangerous than take a reasonable dose of hard opiate

Take 50mg of hydrocodone you will have a nice buzz and you don't kill your liver

For tramadol the limit is 400mg if you want to go higher take Klonopin but again it is stupid, a small dose of hard opiate is much more better
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1.) No it isn't dangerous to take doses up to 700-800mg unless you don't have a tolerance to opiates. It doesn't fuck your liver up unless your taking it with acetaminophen. Again, only risk is if you have a low tolerance then you risk overdose, of course.

2.) That is not true. 300mg is not the ceiling dose. There is no exact ceiling dose but it is not 300mg, its more like 500-600mg. You can still catch a higher buzz over doses of 300mg unless you have a tolerance of course. The maximum daily dose for Codeine is 360mg so obviously doses above 300mg are still effective.

3.) Don't ever go above 400mg of Tramadol, even if you have Klonopin. You always take a risk going above 400mg
 
There is an Opiate potentiation thread here:

http://www.bluelight.ru/vb/showthread.php?t=252569

but in my experience taking another drug just to make the opiate stronger feels like I've taken the usual opiate with the other drug effect just sitting on top (if that makes sense?). It doesn't really improve my experience. But different strokes for different folks, some may work for you.
 
K'd-OUT-in-AZ said:
Yes, carisoprodol increases the effects of Codeine. Nice & warm
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That's the first interesting point I see,

I've read the "ultimate opiate boost", it is a bunch of stupid things for me (Boost a drug does not means have two effects of two different drugs in the same time that's the problem in this thread)

I will try SOMA ! thanks, problem is it is hard to find it in Europe

Is it work also for tramadol ?
 
Warp Renegade said:
There is an Opiate potentiation thread here:

http://www.bluelight.ru/vb/showthread.php?t=252569

but in my experience taking another drug just to make the opiate stronger feels like I've taken the usual opiate with the other drug effect just sitting on top (if that makes sense?). It doesn't really improve my experience. But different strokes for different folks, some may work for you.
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I agree with you when you say : taking another drug just to make the opiate stronger feels like I've taken the usual opiate with the other drug effect just sitting on top
 
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