Codeine inhibits the enzyme required to metabolise codeine, I've found that if I did codeine at around 1PM and tried to redose at 10PM I'd get barely any effect from it.
Codeine inhibits the enzyme required to metabolise codeine, I've found that if I did codeine at around 1PM and tried to redose at 10PM I'd get barely any effect from it.
Don't redose. You will barely get any beneficial effects from doing so. Wait a day. You can still wait 5 hours if you want but you'll notice that the high is just about over.
It's best to wait 24 hours, as codeine hogs the CYP2D6 enzyme resulting in saturation. Therefore any further codeine dosed is not converted into morphine.