Depakote?...

[StaySedated]

psychedelics and ketamine are good options IMO.

true, i guess i can occasionaly use stimulants as well and use opiates to come down and seroquel to knock me out.

although i don't want to become addicted to opiates(again).

 

[K'd-OUT-in-AZ]

Stimulants would probably help you play better.

 

[StaySedated]

Stimulants would probably help you play better.

they do very much, but what comes up must come down and i don't have the will to not reach for a bottle of Klonopin and a few shots of whiskey.

 

[StaySedated]

i wonder if Depakote would help on stimulant comedowns.

 

[StaySedated]

today i took some Adderall and when i came down i took some of the Depakote and it completely wiped out the comedown, and i'm sensitive to comedowns.

i guess theres another use for Depakote, damn i wouldn't have ever guessed.

 

[K'd-OUT-in-AZ]

Maybe I don't have such a hard time coming off Adderall is because Lamictal increases GABA-A release

 

[StaySedated]

Maybe I don't have such a hard time coming off Adderall is because Lamictal increases GABA-A release

i think thats very much possible, although just GABA(not GABA-"A", thats a receptor that GABA binds to) is what would be released.

 

[K'd-OUT-in-AZ]

i think thats very much possible, although just GABA(not GABA-"A", thats a receptor that GABA binds to) is what would be released.

I read that it actually does increase the release of GABA-A

ttp://www.nature.com/npp/journal/v26/n4/full/1395828a.html

"we found that chronic treatment with lamotrigine increased the expression of eight genes and decreased the expression of six genes. One of the upregulated genes is GABA-A receptor beta subunit. This increase in GABA-A receptor beta3 subunit expression was further confirmed by Northern blotting analysis. In situ hybridization revealed that chronic treatment with lamotrigine increased GABA-A receptor beta3 subunit gene expression in CA1, CA3 and dentate gyrus of rat hippocampus. Our findings indicate that lamotrigine may effect GABA-A receptor regulated functions in the central nervous system."

 

[StaySedated]

I read that it actually does increase the release of GABA-A

that doesn't make sense, you can't "release" a receptor. GABA-A is binded to by either a GABA-A agonist(benzos, etc.) or by GABA itself.

i think whatever you read ment it binds to GABA-A.

 

[K'd-OUT-in-AZ]

"I read that it actually does increase the release of GABA-A"

Whoops, that came out wrong I meant increase in GABA

 

[StaySedated]

http://www.bluelight.ru/vb/showthread.php?p=9087515

i found a thread were somebody else feels like Depakote and pregabalin feel similar and makes one feel chilled out.

 

[StaySedated]

http://www.bluelight.ru/vb/archive/index.php/t-540126.html

and another comparing Depakote to pregabalin.

it appears that i'm not the only one feeling this similarity.

 

[K'd-OUT-in-AZ]

The only similarity I find is the fact that they both can produce sedation. And they both have the potential to make me drowsy. Other than that, nothing else. Depakote made me depressed

Be careful, Depakote is notorious for weight gain. It rehab somebody was put on it, an athlete, and he said he gained 15 lbs in a month.

 

[StaySedated]

The only similarity I find is the fact that they both can produce sedation. And they both have the potential to make me drowsy. Other than that, nothing else. Depakote made me depressed

Depakote actually reversed my depressed mood, but it does make me drowsy and calm.

benzos also reversed my depressed moods, i guess incresed GABA activity has an antidepressant effect on me(and likely one of the reasons i abused GABAergics so much).

 

[StaySedated]

well i sucessfully got of the temazepam part of my benzo dependence, now starts the disdain of getting of the clonazepam.

hopefully the Depakote still helps.

*also, for some reason the Depakote pills i just got from the pharmacy are white with "A511" printed on them, while the original pills were dark grey with "HC" and an weird upside down "e" printed on them.

are these new ones generic or did the pharm company change it's look or did the pharmacy get my pills mixed up?(it wouldn't be the first time, i once got my flurazepam mixed up with some antibiotic pills)

 

[StaySedated]

well i'm still taking the Depakote and its still working.

 

[K'd-OUT-in-AZ]

well i'm still taking the Depakote and its still working.

Great job, good luck with the clonazepam taper.

 

[StaySedated]

i'm planning on trying to get "high" on the stuff because its been chilling me out so much and so consistantly(the feeling is very similar to pregabalin and gabapentin).

the pills are 500mg, what do you think would be a good dose?

 

[StaySedated]

Great job, good luck with the clonazepam taper.

yeah when i get down to a low enough dose i'm going to switch to diazepam.

 

[K'd-OUT-in-AZ]

i'm planning on trying to get "high" on the stuff because its been chilling me out so much and so consistantly(the feeling is very similar to pregabalin and gabapentin).

the pills are 500mg, what do you think would be a good dose?

lol, you can't get high on Depakote. If you take more you won't feel any different except for more side effects. It doesn't make you cozier like pregabalin or gabapentin. Go ahead and try but it won't do anything. Just go up to the next dose and see how you feel. In my opinion that's like trying to get high on Lithium. Desperate people will try, like the guys I sold it to lol, I said "just smoke some weed with it and you'll feel it" I forgot what they gave me for it. But hey, I've never tried to get high on Depakote...

Honestly I'd like you to try it, you reported on the effects of shooting Seroquel so this may be interesting also.