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Why do most drugs that you smoke take a while to take effect?

Inhaling anything hits you faster than IVing. Proven fact. However, with a shot you're getting all of it at once whereas with smoking you need to take successive hits which makes it take a little bit longer to take effect.
But bud always hits me in about 30 seconds. When you smoke a cigarette, the nicotine hits you in 7 seconds.
 
datSTIMfreak said:
Inhaling anything hits you faster than IVing. Proven fact. However, with a shot you're getting all of it at once whereas with smoking you need to take successive hits which makes it take a little bit longer to take effect.
But bud always hits me in about 30 seconds. When you smoke a cigarette, the nicotine hits you in 7 seconds.
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but the best part or peak of the high takes a little bit...like the buzz with alcohol as opposed to being drunk
 
Never smoked any drug that wasnt almost instant after inhaling.
 
datSTIMfreak said:
Inhaling anything hits you faster than IVing. Proven fact. However, with a shot you're getting all of it at once whereas with smoking you need to take successive hits which makes it take a little bit longer to take effect.
But bud always hits me in about 30 seconds. When you smoke a cigarette, the nicotine hits you in 7 seconds.
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uhhhhhhhhhh no
With smoking it still needs to go through alveoli in your lungs to get to blood.
 
^ Yes

The fucktard above him, no, I wrote what I meant. There are MANY drugs that have no effects at all when smoked until a few minutes to 30 minutes after inhaled (cougjwh-018cough) and the 'come up' is a few seconds, a few minutes after you smoked you're walking around not stoned, a few seconds later you're starting to get trails, a few seconds later you're completely tripping. Then again that's just me. I don't seem to have much of a comedown though either, it's always only a few minutes of comedown before I'm normal again if at all.
 
The Network said:
^ Yes

The fucktard above him, no, I wrote what I meant. There are MANY drugs that have no effects at all when smoked until a few minutes to 30 minutes after inhaled (cougjwh-018cough) and the 'come up' is a few seconds, a few minutes after you smoked you're walking around not stoned, a few seconds later you're starting to get trails, a few seconds later you're completely tripping.
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lol dont get mad at me i spent the whole thread defending what you were trying to say
 
The Network said:
You all must have really shitty watches. I've never heard of weed hitting anyone faster than about 10 minutes. And JWH-018 takes over 20 minutes to hit me sometimes. So do other things that I smoke.
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Well, that makes sense if youre a stoner. They never hear of anyone doing anything.

It took 5-10 minutes for weed to hit me the first time I smoked. But nowadays I feel it within 30 seconds and if I smoke quickly Im pretty much riding the peak after like 5 minutes.

Cigarettes hit me in 0.5 seconds, salvia hits me in 10-40 seconds, the most weed has EVER taken to peak for me is 20-25 minutes.
And yes onset is often faster through inhalation than by injection. With the more addictive and known narcotics they are both instant but injection will give a better rush. Stop acting like a professor, were druggies here man.
 
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Mmmm, no one has actually answered the question. Why are absorption rates different, even with the same drug?

Personally, there have been times when i'm bonging and I feel it as soon as I inhale, like not the full effects but you just know... Other times I felt completly fine and then in 10 minutes i'm off my face. Different weed though, and weed is so variable in its effects on people. And cigarettes is immediate. OT but apparently IVing nicotine would seriously fuck you up/
 
Lord said:
Well, that makes sense if youre a stoner. They never hear of anyone doing anything.

It took 5-10 minutes for weed to hit me the first time I smoked. But nowadays I feel it within 30 seconds and if I smoke quickly Im pretty much riding the peak after like 5 minutes.

Cigarettes hit me in 0.5 seconds, salvia hits me in 10-40 seconds, the most weed has EVER taken to peak for me is 20-25 minutes.
And yes onset is often faster through inhalation than by injection. With the more addictive and known narcotics they are both instant but injection will give a better rush. Stop acting like a professor, were druggies here man.
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Woh woh woh now. You say onset is often faster through inhalation than injection?! Injection - Straight into bloodstream then into the brain, Inhalation - Gots to go through all sorts of mechanisms before it hits the brain! Where is your logic?
 
I've never really smoked anything that wasn't almost instantaneous either so I can't really see your side of your defensive arguement that some drugs hit you in milliseconds and some drugs take 30mins-1hr?

I feel marijuana as soon as I exhale it. I've tried meth and that's instant too, exhaling usually does it for me.
 
Well I don't have a fuckton of experience with drugs but I would still think I'd know the difference between coming up a ramp and running into a wall going 900mph and going straight to the top(which is probably the best metaphor for how I experience most drugs).
 
Smoking Heroin,cocaine(crack or freebase),and meth puts the drug into your bloodstream and brain in a few seconds,like 8-10 seconds.Weed sometimes takes a minute to reach full bloodstream effects or sometimes in the case of "creeper bud" for some reason you can smoke some of that and think you are high,and then 15 minutes later you are really high,I suppose that is something in the "creeper weeds" genetics? or something that makes the full high take a while hence the "creeper bud/weed" name,for salvia I never done that,but for most drugs they enter the lungs when smoked and go into the lung tissue,which is rich in blood and blood vessels then to the heart and then to the brain,the blood in a normal person will go through the lungs to the brain,and other parts of the body and back to the lungs in a very short amount of time,less than a minute for sure,so I don't know why some things may be slower absorbing into the blood through the lungs,the only thing that has done that to me is certain types of weed callled "creeper bud" and most other drugs are very quick to hit the brain after smoking,so it may ne the individuals lungs and body that make a difference,I can think of nothing else that would effect the absorbtion of drugs via smoking that would be different except for the person..
 
KingBlueTwista said:
Woh woh woh now. You say onset is often faster through inhalation than injection?! Injection - Straight into bloodstream then into the brain, Inhalation - Gots to go through all sorts of mechanisms before it hits the brain! Where is your logic?
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I agree, smoking some drugs hits you faster or as fast as IVing them. Crack vs IV cocaine, smoked vs IV meth (seems about the same to me) are two examples I can think of. When I smoke weed, which I do many times daily, I start feeling each hit as I'm exhaling or slightly after exhaling the hit, then I continue to get higher for 5-20 minutes, plateau for a while (hard to say how long because I usually smoke on a bowl for 20 or 30 minutes, but probably 1-2.5 hours), then come down gradually.

With smoked heroin it's hard to say. I've only smoked it a few times, but I recall feeling it slightly after exhaling, whereas with IV there's a slight delay as well. The thing about IV use is that you put the entire dose in at once whereas with smoking it often takes a little while to consume the entire dose.

Smoked DMT seems pretty similar in onset to IV DMT as well, to give another example.

When you smoke a drug it doesn't really go through all sorts of mechanisms before getting to your blood, it's pretty quickly into your blood. And when you IV, depending on which spot you hit, the blood often circulates through other organs before hitting the brain.
 
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