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  • BDD Moderators: Keif’ Richards

Is 5 HTP Dangerous?

Violenza666

Violenza666

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Dec 15, 2009
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The pits of hell
I am on Valium, Klonopin, Opana, Roxi, Soma, Vitamin B12 injections, Ibuprofen 800... My friend is taking it and she says it's great. Gives her a mood lift ect. I am apprehensive because I am on a variety of medications. Any input would be great. Thanks :)
 
it is safe if you are not taking any serotonin increasing drugs like SSRIs, MDMA, amphetamines, DXM, etc.

the meds you mentioned won't have any interactions.
 
Violenza666 said:
I am on Valium, Klonopin, Opana, Roxi, Soma, Vitamin B12 injections, Ibuprofen 800...
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lol with that combo 5htp should be the least of your worries.

no its not dangerous. its not really suitable for long term use though.. if you use it for more than a few days in a row it can actually be counterproductive because it causes your serotonin receptors to turn off (downregulate.)
 
.Lucid. said:
lol with that combo 5htp should be the least of your worries.

no its not dangerous. its not really suitable for long term use though.. if you use it for more than a few days in a row it can actually be counterproductive because it causes your serotonin receptors to turn off (downregulate.)
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Yea... I get the "death cocktail".. LOL

I only take benzos in the morning and I try to avoid alot of opiate use at night even if I am uncomfortable. I was just wondering if they were good for an occasional mood lift on a shit day. If I am in that much pain at night no amount of medication will put me to sleep. It sucks. Thanks for the replies though :)
 
5-htp had pronounced anxiolytic effects on me. Enough to bring me from non functioning to I feel good. Moderate mood boosting effects as well. 10 mg every few days effectively augments low dose ssri use, I assume It makes up for the decrease in serotonin efficiency. Peripheral conversion to serotonin does present risk to heart valves if using long term and at high doses.
 
I've read a few posts on here about people having adverse reactions with 5-HTP and alcohol. So that's something to consider. From what I remember of the threads it didn't seem to happen to everyone so maybe you will be fine. However, as I'm sure you know, with the drugs you listed, alcohol is already asking for trouble at the wrong dosage (when mixed with benzos and opiates)
 
.Lucid. said:
^ 10mg? lowest ive seen is 50mg.. i cant imagine 10mg doing anything
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I said to augment ssri use. With zoloft 50-100 mg, the potency of 5 htp was significantly enhanced. I would say about 10-20 times normal. 50 mg of 5 htp resulted in enormous pupils and confusion. You can measure out low doses with an accurate mg scale. 10 mg every other day resulted in a huge increase of zoloft's effectiveness.
 
I would just stay away from 5-htp I was on that for months and it barely did anything except make me tired, and considering everything else your on I dont see the point.
 
LonE1 said:
I would just stay away from 5-htp I was on that for months and it barely did anything except make me tired, and considering everything else your on I dont see the point.
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You could slide yourself into depression that way.
Each passing day you downregulated your serotonin receptors and were gonna need more and more 5htp.
 
.Lucid. said:
^ lol.. youre not suppose to use it long term though.
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I was abusing mdma fairly often, and was told by my doctor that it might be a good idea (although this doctor is pretty stupid compared to my new one) by taking it regularly.

I noticed no difference off or on it, depression or anxiety wise, and all it did was make me slightly drowsy.

I think the stupid if fuckin stupid personally but in my opinion of course ;)
 
I used to take 100-200mg with speed and weed, and often Id take it on the same day as pretty much any other drug I did. I noticed that when I was using 5-HTP, my left eye would start shaking if I did too much weed or too much of everything. Just because its legal doesnt mean its harmless.
 
Lord said:
I used to take 100-200mg with speed and weed, and often Id take it on the same day as pretty much any other drug I did. I noticed that when I was using 5-HTP, my left eye would start shaking if I did too much weed or too much of everything. Just because its legal doesnt mean its harmless.
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I agree with you there.. "Just because it's legal doesn't mean it's harmless". Your eye would twitch? Weird. I am still on the fence about this shit. I heard it's a good suppliment from quite a few people, but I have also heard other things which is why I am asking questions. Better to be safe than sorry even if the drug is OTC. I am probably gonna stear clear of it right now. I am not "sure" about it, and I never do anything I am not "sure" about. Thanks :)

I was considering using it during PMS... thinking it might help. But now I am not so sure.
 
*also i think 5-HTP may have risks of raising blood pressure/hypertension as agents that increase serotonin usually have this as a side effect.

so if you have problems with high blood pressure or heart problems i'd avoid 5-HTP.
 
Lord said:
I used to take 100-200mg with speed and weed, and often Id take it on the same day as pretty much any other drug I did. I noticed that when I was using 5-HTP, my left eye would start shaking if I did too much weed or too much of everything. Just because its legal doesnt mean its harmless.
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Twitching is a side effect of too much serotonin...

You were pushing Serotonin Syndrome.
 
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