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What exactly is going on when you eat shrooms?

One fella came up with a magic statistic that taking LSD reduces your brain function by 10% (over how many trips and at what frequency and for how long? jeez)

quaintly I put it to the fellow that I could destroy him in a mathematics competition any day
 
NA/AA people usually have condescending opinions about drugs, especially hallucinogens for some reason. They probably don't mean any harm, although coming up with myths harms their reputation.

It's just good for moral support, not so much for harm reduction.
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well said my thoughts exactly


BTW, damn this no0bie thread really took off... especially for a basic drug discussion (or more like lounge) question lol.
 
predator said:
My friend said that when he went to alcoholics anonymous they told them your brain is bleeding when you eat shrooms. Anybody know what's really going on when you eat MM?
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HolyFacepalm.jpg
 
After reading some interesting comments regarding 5HT receptors and serotonin etc above. I was wondering what the effects of taking 5HTP before shrooming/tripping might have ?

I know taking 5HTP supplements help recover and to an extend can amplify the effects of MDMA on depleted serotonin.

I ask this as ive been taking 5HTP for the last couple of weeks to help recover from MDMA sessions, ive not yet tripped whilst on these as im waiting on my next batch. Will this heighten my next trip.

Cheers
 
5-HTP before tripping will saturate the receptors thus REDUCING the trip... it intensifies MDMA because MDMA functions largely by massive serotonin release... but if the receptors are saturated, the psilocin can't bind to a SERT to exhibit its effects.
 
Mushrooms contain Psilocybin, Psilocin, Baeocystin and Norbaeocystin.

Psilocybin, 4-PO-DMT, breaks down into Psilocin, 4-HO-DMT, which is the main component in the trip you achieve. However it's believed that Baeocystin and Norbaeocystin are active in their own right, which would explain why people experience different effects from mushrooms with different alkaloid content.

Psilocin is a 5ht2a, 5ht2c and 5ht1a agonist, 5ht2a agonism is known to cause psychedelic effects and all traditional psychedelics are 5ht2a agonists.

They do not make your "brain bleed", the only negative effects you should be worried about are, during the trip:
- Nausea
- Anxiety
- An unpleasant experience
- Vasoconstriction (Not significant unless you take a huge dose)

And after the trip:
- Tolerance
- A little vasoconstriction for a day or so with larger doses

In relation to other drugs though psychedelics are among the safest drugs known to man, they make weed look like heroin in relation (A little exaggeration there but even though weed is very safe, psychedelics are far physically safer unless large doses are continually taken every day, which is made impossible by tolerance)

Hope this helps.
 
Did you really just say that psychedelics are among the safest drugs known to man?

Apparently you haven't heard of irreversible schizophrenia and depersonalization? Or the fact that mushrooms have been linked to more suicides than acid - ironic considering that mushrooms are supposed to be far gentler...

Lets also not forget the numerous hospitalizations and deaths from psychedelic ODs... its no joke. Marijuana can not kill you. It may feel like it... but pyschs definitely can. Directly AND indirectly.

And also I can tell you from experience that tolerance hits a certain level and then doesn't go any higher... for me it was 30mg of 5-MeO-AMT... once I hit that tolerance ceiling, the same dose produced the same trip for the same period of time... for literally every day for at least a month.
 
You did 30mg of that toxic crap every day for a month? Sweet Jesus. Just what kind of brain damage were you shooting for?

Did you ever do time in a mental hospital because of it? Not dissin', actually wondering.
 
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How can psychedelics directly kill you? Physically? What are you talking about? Most OD's that have people ending up in the hospital happen because people freak out, not because they are physically going to die due to dosage.

Psychedelics have among the highest safety indexes of any drugs...and whats all this about schizophrenia and depersonalization? In what way have mushrooms been linked to more suicides than LSD?! Sources? I mean, more people do mushrooms, but I seriously doubt the suicide rates are high enough to be statistically significant in any way...

Man, thats not how tolerance works, or at least I cannot imagine how it wouldn't produce any kind of tolerance, if the effects literally did not change as you say they didn't, somebody ought to study you! lol there's some weird pharmacological shit going on in your brain..
 
DwayneHoover said:
Yes, you hit the nail on the head.... your friend is a TOTAL idiot! 8) You come in a close second for not being able to be bothered to lift two index fingers and google to find any one of like 500 sites and FAQs with encyclopedias full of detailed scientific info about shrooms.

Isnt there any way to have a robot filter out such things and redirect them to dumblazydrugquestions.com?
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Only if posts like this one can be filtered out and redirected to arrogantpricks.com ;)
 
mr.mackey said:
How can psychedelics directly kill you? Physically? What are you talking about? Most OD's that have people ending up in the hospital happen because people freak out, not because they are physically going to die due to dosage.
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keep in mind that some psychedelics, especially the ones that escaped from the labs in the past 10 - 15 years, can have physical side effects. Taking 20 times the recreational dose of those dragonfly compounds (i forgot which one it was where mislabeling caused some deaths earlier this year) for example would be very ill adviced. these effects are, IIRC, vasoconstriction, heart rate increase, temperature increase, and whatever kills you when you snort 2C-T's.

That's why i'd personally rather just eat mushrooms :)
 
Aloysius said:
taking 20 times the recreational dose of those dragonfly compounds (i forgot which one it was where mislabeling caused some deaths earlier this year)
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You talking about the incident where somebody thought they was nickin a line of ket from their mate (who wasn't in at the time) but infact nicked a line of crystal bromo-dragonfly? They didn't die if that's what you're talking about..

There have been deaths linked to aMT, 2c-t-7 and others.. but true pschedelics are pretty hard to OD on.. i still don't believe they are extremely safe.. think of the people who, ok shouldnt have done them but did, and ended up in psyche wards for massive amounts of times.. sometimes with prolonged (maybe permanent) psychological problems from too much psychedelic use / traumatic experience caused by psychedelic drug use..

Remember these (most) stories wouldn't go into any papers and probably wouldn't go into any statistics.. especially if the person was only taken in days after the drug intake and never told anyone about it..
 
The deaths due to 2C-T-7 (im pretty sure as of yet there are no other 2C-T-x's to have killed anybody, but correct me if Im wrong) are thought to be because they were taken with MDMA, ephedrine or cocaine, all of which are stimulants, and I think the common consensus is that the fatalities were caused by 2C-T-7's MAOI properties...

Im not saying its impossible to die taking psychedelics, that would be silly, but in comparison to most recreational and pharmaceutical drugs, the majority of them have a huge margin of safety. I think the risk of death from most psychedelics is pretty low, even with things like 2C-E and the like, considering the number of research chemicals on the market in the past year, the amount of people using them, and even some of the reckless behavior using them, I think its a good sign that there have ONLY been a handful of fatalities. I think if you add them all up theres probably in the area of less than 20 deaths (just from scrounging around erowid, at the high end the number seems to be 16, at the low end 9, maybe when I have more time I'll go about and find a more accurate number) which is far from being "numerous" in my opinion.

the part that I was concerned with was the idea that mushrooms (which I too enjoy eating ;)) "have been linked to more suicides than acid". No offense to Magick kat, Im not picking on you or anything like that, I just have heard people say things like that often and I have no idea where they got that information.

And how do you define extremely safe? For example caffeine has a more dangerous effective dose/lethal dose ratio than LSD and psilocin, yet I would consider it to be a fairly safe drug. On the other hand alcohol has by some estimates, a ED/LD ratio worse than cocaine. And then theres the idea of psychological safety, I mean shit, most of life isn't "safe" from a psychological standpoint...lol sorry about the ranting style of my post, had a cup of coffee not too long ago...
 
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