• Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

Status
Not open for further replies.
Has anyone here ever had the Buprenex ampules? If so, how were they?

I'd love to get some of those for the last part of my taper coming up in the next three or so months. I kinda just went on a three week heroin binge and I'm still not feeling right being back on the Subs, still getting anxiety and sweats three days after my last shot. Blah. I also took the Sub too soon after my last shot - I got kicked into precipitated w/d's which was NOT fun, especially AT WORK. Ugh. Good thing they only lasted about 45min-1hr for me. But still :!
 
Has anyone here ever had the Buprenex ampules? If so, how were they?

I'd love to get some of those for the last part of my taper coming up in the next three or so months. I kinda just went on a three week heroin binge and I'm still not feeling right being back on the Subs, still getting anxiety and sweats three days after my last shot. Blah. I also took the Sub too soon after my last shot - I got kicked into precipitated w/d's which was NOT fun, especially AT WORK. Ugh. Good thing they only lasted about 45min-1hr for me. But still :!

I have not had Buprenex ampules, however, the concentration is somewhat low for most people. What I am using is around that concentration, because I only need to use about 30mcg in 8 units of water. Buprenex is slightly more dilute, 30mcg in 10 units of water.

I do think that it's a decent concentration for people with low tolerance though.
 
I have not had Buprenex ampules, however, the concentration is somewhat low for most people. What I am using is around that concentration, because I only need to use about 30mcg in 8 units of water. Buprenex is slightly more dilute, 30mcg in 10 units of water.

I do think that it's a decent concentration for people with low tolerance though.

Hmm, so that would probably only be good in the final, final step of my taper. And I suppose that one would expect the concentration to be quite low. Isn't the standard dose of bupe for pain management like 500mcg max?
 
yes thats with the i.v. roa. taking it under the tounge 50mcg would be 2-3mg which imo is the ceiling pretty much.
 
Hmm, so that would probably only be good in the final, final step of my taper. And I suppose that one would expect the concentration to be quite low. Isn't the standard dose of bupe for pain management like 500mcg max?

I think that for adults, they advise 300mcg per shot (1ml), up to 2 shots in a row. I find it kind of useless to re-dose buprenorphine until a few hours have passed by though.
 
ive been on bupe 2 years and i noticed this past year that once every few months ill wake up really shaky and start puking til im about to choke. does neone else who is on bupe maintence exp. nausea ever? this question isnt for people with zero tolerance to bupe becuz yall will puke unless u take a low enuff dose. im on 1.5mg day iv roa

I get this sometimes too. I IV 1-2mg's of sub and feel naesous and sort of "noddy" or real tired afterwards. I notice i get neasous a lot more when im doing stuff like excercising.
 
My first experiences with buprenorphine were with the buprenex ampoules about 12 yrs ago, The word back then was that you shot 2 amps into a muscle daily for 3 or 4 days `and it let you off a heroin addiction very lightly. And it did. And they had a nice mellow buzz. I was astonished when a friend took part in the RB trials and said they were giving em 8mg tabs. Wow. I definitely can confirm the less is more. Back then it was said that if you shot more than 3 ampoules it "stopped working". And, lo and behold, it felt distinctly shitty. And I've found still, to this day, like so many others, that 1mg or less of subutex produces the best results.

I am on board with the theory of buprenorphine out competing naloxone for the receptor sites and there being no difference in subjective effects between suboxone and subutex. I *think* they feel the same to me. Think. But i must wonder....that is a MASSIVE dose of naloxone. In a general heroin overdose 400 mcg is the frequent dose required to reverse the effects of the heroin. 400 mcg. There is 5 times that much in a single 8/2 suboxone. Now, granted, oral absorbtion is quite poor; at least a gram is needed to produce the effects of 400 mcg. But i.v. is another story entirely. Now, in cases of buprenorphine overdose, naloxone doesnt work so well, because buprenorphine has a higher affinity for the receptors. But it does have some effect. And with all the amazing recent work being done with ultra low dose naltrexone and other antagonist therapy, i must wonder about that naloxone...wonder, but not quite ready to switch back from subutex to suboxone :D
 
i dont really understand this, so your saying the 16mg of buprenorphine ive had either subbed or snorted in the past is still in my system and getting stronger? :P i just did a tiny line and now its getting weaker, its gotta just be tolerance going up to quickly.

seriously if someone with no tolerance to opiates put 16mg buprenorphine under their tounge and whilst on benzos they would be dead im sure, im fine as ive spread it out :)

Eh, its hard to explain. Granted 16mg+ benzo's wouldbe devastating to somone with no tolerance, and spreading it out is helping, heres the best analogy I can give:

If you are standing still and get hit by a train (suboxone) going at 40 mph, you get hit with 40mph of force. But if you are running away at 10mpg, you only get hit with 30mph, however, once you are on the stuck \to front of train you'll be going 40?

Does that make any sense? Suboxone's half life is like 36 hours, so I'd guess it's still in you, its just not hitting you at same speed?

Or another example:
Doing 1g of heroin over 1 hour in 3 shots, each shot youll get more jammed but be able to counter it/stay awake.
Doing 1g at once the rush might be too high and you pass out stop breathing?

Eh? Best I could do to explain this
 
I am gonna wait as long as I can before I do this sub

I already feel them coming on :\
 
I am gonna wait as long as I can before I do this sub

I already feel them coming on :\

Huh? You can feel a drug coming on by looking at it 8o wish I could do that, I'd just window shop at pharmacies all day.

Seriously though, what do you mean, Im confused as hell?
 
I already feel the withdrawal symptoms coming on, gonna wait long as I can.
 
Eh, its hard to explain. Granted 16mg+ benzo's wouldbe devastating to somone with no tolerance, and spreading it out is helping, heres the best analogy I can give:

If you are standing still and get hit by a train (suboxone) going at 40 mph, you get hit with 40mph of force. But if you are running away at 10mpg, you only get hit with 30mph, however, once you are on the stuck \to front of train you'll be going 40?

Does that make any sense? Suboxone's half life is like 36 hours, so I'd guess it's still in you, its just not hitting you at same speed?

Or another example:
Doing 1g of heroin over 1 hour in 3 shots, each shot youll get more jammed but be able to counter it/stay awake.
Doing 1g at once the rush might be too high and you pass out stop breathing?

Eh? Best I could do to explain this


ok thanks, odd with no tolerance i was able to snort 16mg spread out over 48 hours *more to that now* with added xanax along the way and feel fine hehe, ill give it a break and try and get some of the nice feelings back.
 
hey, totally new user here, how's it going guys.
anyway, couple of questions about bupe.
so it says 1-2mgs is a typical recreational dose for people with little to no tolerance. i've got 0.4mg sublingual tablets and literally zero tolerance (this will be my first opioid experience). I'm keen to keep my first dose as low as possible to avoid puking my guts out everywhere, so will just taking one of these (so only 0.4mg) actually do anything for me or should I take a couple to actually get a decent dose?

i'm also wondering whether to crush up the pills and snort them, or take them sublingually. i've seen the bioavailability of snorting them is higher, but which would you guys recommend?

one final question, i've got a bit of diazepam too, would taking one of those with the bupe be safe/would it actually improve the feeling?
thanks.

eta: oh, and would just generic over the counter antihistamine help at all with any nausea were i to get any?
 
Last edited:
I'd snort half of that pill, so .2 and see how you feel. Buprenorphine as your first opioid experience is pretty wild. You are gonna be nodding good.

Be careful, do a tiny line and see how you feel, repeat if necessary.
 
Hey everyone, I am back. Feel free to ask me any questions you might have. :)

How are you all doing?

I'm on suboxone the longest I've ever been :) about 3 weeks. Although, I know that tomorrow I will use Oxy.

I've set it up so that I've tapered over the last 3 days so that I will feel the effect from it tomorrow. I've only had 1mg today, and I actually don't feel that bad at all. i know sub has a long half life but I was expexcting to feel pretty crappy. especially because my first few days on subs I was taking probably 12-16mg.

But yeah, it was kind of a good feeling to stay on it that long.

I'm hoping that my tolerance to full opiates will be lessened during this time.
 
So I finally manned up and took a sub and I gotta say I'm dissapointed..I have a few broken pill so I took what I figured was 2mg insuffilated..I waited about 20 mins and didn't feel anytyhing so I took approx another 2mg SL... I waited another 20min and the chills went away but I want to nod like I was told..so I took snorted another piece and nothing so I give up..It did its job by takin the chills away but I'm not high and dissapointed

Can I bust another 2-4mg out and get high or is it just not gonna affect me recreationally due to my tolerance?
 
Damn that's what I figured....what about a whole 8mg pill or two more of them

Sub isn't like other opiates, the more you take doesnt mean you'll feel it more or "get more high/nod" If you already have a tolerance to strong opiates theres no chance pretty much of getting any sort of high with suboxone. Use them to get clean.
 
Thanks for the response


I just read over page 1 and saw it said had to wait 2 days until I take another opiate...that's some shit.. I thought 24 hours was good..pocket full of money and can't get high with it..that sucks
 
Status
Not open for further replies.
Top