My theory on the cause of Restless-Leg Syndrome

[G-G]

It seems that no one in the medical field has agreed on a cause for the syndrome. I was thinking, one evening while kicking my leg after taking a single Benadryl™, maybe it is caused by the anti-cholinergic activity? I assume that the syndrome is induced by the anti-cholinergic activity of Diphenhydramine, so wouldn't it make sense that something which is pro-cholinergic would cure the symptom?

I would like to know if my little theory has any grounds in science. %)

 

[Sprout]

I have horrible RLS, and it runs in my family so I doubt it's purely chemical, more genetic.

 

[G-G]

I have horrible RLS, and it runs in my family so I doubt it's purely chemical, more genetic.

But doesn't the possibility of a Cholinergic-related problem still remain? Maybe your gene's are pre-disposed to develop a relatively more inhibited cholinergic system.

 

[avcpl]

Great, now please help me with my restless penis syndrome.

 

[hobhead]

^^^ "whip it, whip it good....."^^^^

 

[K'd-OUT-in-AZ]

Well the first line treatment are Dopaminergic agents that increase dopamine that regulates muscle movement.

avcpl: Take a combination of Lyrica and clonazepam. Miracle.

 

[G-G]

Well the first line treatment are Dopaminergic agents that increase dopamine that regulates muscle movement.

avcpl: Take a combination of Lyrica and clonazepam. Miracle.

What does Dopamine NOT do?

And is there really Restless-Penis Syndrome? lmao. Or are you referring to excessive horniness?

 

[K'd-OUT-in-AZ]

I missed the Restless-Penis Syndrome remark. LOL

 

[happygoluckygal]

Are you talking about RLS as related to w/d's...or the chronic syndrome many people suffer from that is unrelated to opiate use?

One thing I can say I can see has helped a lot of people is Quinine, which is found in tonic water. Of course, meds like Lyrica and Requip have been successful for a lot of people (non opiate related)...but again, the Quinine really does the trick for a lot of people...some alone, and some in addition to Rx meds.

RLS related to opiate w/d is short lived and will eventually resolve after detox is complete. For some, it lasts a while, though.

 

[G-G]

Are you talking about RLS as related to w/d's...or the chronic syndrome many people suffer from that is unrelated to opiate use?

One thing I can say I can see has helped a lot of people is Quinine, which is found in tonic water. Of course, meds like Lyrica and Requip have been successful for a lot of people (non opiate related)...but again, the Quinine really does the trick for a lot of people...some alone, and some in addition to Rx meds.

RLS related to opiate w/d is short lived and will eventually resolve after detox is complete. For some, it lasts a while, though.

I was actually talking about RLS not related to Opiate withdrawal. I was thinking maybe it is related to a lack of acetylcholine.