KAYLA,
The thread you linked was referring exclusively the M1, M2, M3 muscarinic acetylcholine receptor antagonists like diphenhydramine (Benadryl, Sominex), atropine (active component of Belladonna), scoploamine (Devil's Breath), and a variety of antiparkinsonian medictions with similar pharmacologic activity. These receptors are responsible for, among many other things, initiating and maintaining higher thought processes, as evidenced by their regional distribution, with higher numbers of receptor sites in the cortex than most other regions of the brain. In lower brain regions associated with movement, muscarinic blockade liberates dopamine and potentiates its postsynaptic action, enhancing the efficacy of the antiparkinsonian meds.
However, the adverse cerebral effects of these drugs are extensive, and their use should be avoided unless absolutely necessary. Some include: amnesia, working memory impairment, learning deficits, inhibition of REM sleep, and in higher doses (or susceptible individuals), delerium and psychosis.
HOWEVER, contrary to your speedy [and somewhat silly] conclusion, phencyclidine is not an anticholinergic in the conventional sense of the term, as it appears to have negligible affinity for the aforementioned receptors, binding instead to the ionotropic nicotinic acetylcholine receptors, with high selectivity for the alpha7 subtype. Selective blockade of this receptor does not result in the so-called "anticholinergic syndrome," nor are drugs that possess such an action generally referred to as "anticholinergics." That moniker is typically reserved for compounds that exhibit selective muscarinic antagonism, a quality which PCP decidedly lacks.
Also, Hallucinogen Persisting Perception Disorder [the primary topic of the linked thread] has very little to do with what you initially asked, as it hasn't been firmly established whether anticholinergics like Benadryl can actually cause the disorder at all; nor, either, does PCP exert its hallucinogenic/neurodegenerative effects via its incidental nicotinic affinity. HPPD is a purely visual phenomenon with no relevance to what I can only guess is happening to you [from what I can gather from your scattered posts], which I suspect is a legitimate drug-induced neurologic and/or psychiatric condition. Like the previous poster said, you sound pretty fucking distraught, and this is based solely upon the odd, frenetic tone of your posts, all of which appear to be linked in some way to a presumed (impossible) "acetylcholine deficiency" that you're determined to implicate in whatever horrid time you might going through.
Just go see a doctor or something.
