howdy sustanon, once you start taking it more than the prescribed/ optimun amount you can start doing damage pretty quickly. but its also dependant on a few other variables such as your general health, any diseases or illnesses you may have had or currently experienceing.
the way that medications are viewed is:
up untill a certain point OTC painkillers can be used, once past that the optimum treatment is to try a different medication which selectively or more generically targets pain, over using lower order medications can actually do more damage without adding any thereputic value.
paracetamol or Ibruprofen= good for general pain
paracetamol or Ibruprofen + codiene= good for more severe pain including the need for some analgesia (codiene)
Taken From
analgesia Brochure
MILD TO MODERATE PAIN
□ Paracetamol (Panamax®, Febridol®, Dymadon P®)
□ Naproxen (Naprosyn®, Inza®, Proxen®,
Naprogesic ®)
□ Tramadol (Tramal®, Zydol®)
MODERATE TO SEVERE PAIN
□ Oxycodone (Endone®)
□ Oxycodone (OxyContin®)
□ Morphine (MS Contin®)
when clients come in looking for a review of their use of OTC pain killers the medical officers usually do a maths conversion of the amount of codiene that a person is using. This allows The prescribers to judge what level of opiate dependance/intoxication is and what the target for maintenance would be. example would be a person taking x amount of neurophen plus would need approximately x amount of a opiate maintenence to achieve the same afect the person is getting with the physical harms done from injesting the OTS combinations. Also there is the opportunity for GP's to prescribe codiene phosphate by itself.
More info taken from the
Chronic Pain Management Clinical Flowchart
When opiates are to be trialled:
Opiate Equivalence Table
Opiate equivalence tables are useful when transferring between
medications, including the commencement of supervised dosing
of methadone or buprenorphine for the management of opiate
dependence.
The following medications are roughly equivalent
over a 24-hour period (based on Therapeutic Guidelines):
• Codeine 240mg
• Morphine 40mg
• Methadone 10-15mg
• Oxycodone 20-30mg
• Buprenorphine 2-4mg
Significant dose escalation above these levels is often only performed
after discussion with or review by other medical colleagues