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2,5-dimethoxy-4-astatophenethylamine (2C-A)

xenon is extemely hard to attach to anything, u may be able to place it somewhere on the molecule if it's attached to a fluoro atom
 
How about silanyl or methylseleno groups.

edit. or should it be silyl? Either way, silicone analogs of alkanes would be an interesting group to pursue imo...
 
dread said:
How about silanyl or methylseleno groups.

edit. or should it be silyl? Either way, silicone analogs of alkanes would be an interesting group to pursue imo...
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methylseleno has been tried by shulgin "2C-SE" in pihkal.
 
At what, a fraction (roughly 1/4) of the 10's of milligrams of parent compound required? Haha.
But, yes, you'd get *some* secondary effect... sidestepping that whole "I hope when it breaks off it doesn't destroy my neurons with reactive products never mind how to make it and get it into me" technicality thing.

There may well be atoms that can be substituted how the halogens are further down the periodic table that have not been discovered yet that sit on 'islands of stability' irt. radiostability that wouldn't make you die a horrific death from irradiation, but the only point in making them would be for 'look at my ridiculous substitution' dick-sizing competitions :P . They might not even be active at all, as they wouldn't fit in the receptor pocket, or perhaps not penetrate the BBB.
 
MattPsy said:
Haha
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Assume for argument's sake that the theoretical xenon on the phenyl is displaced Sn2-style in the CNS and that 25mg of the parent compound was dosed.

So then you'd have roughly 10 mg of xenon in the brain, or 8x10^(-5) moles.

According to Wiki, xenon has 1.5 times the potency of N2O. 1.2X10^(-4) moles of N2O fills a 2.7 mL balloon at STP.

OK you're right.
 
Still not sure if i'm inferring the appropriate emotional content from the text (hell, even my own - everyone's autistic on the internet), but I didn't mean to 'attack' you or anything, if that's how it was taken. Peace.

Anyway, the average N2O whippet contains 8 grams of N2O (using the equivalence you noted, 8 divided by 1.5 is 5.33), so yeah, potency is a bit lacking :) .
on a side note, I REALLY WANT TO TRY XENON.
 
It's been known for quite long that xenon actually may form compounds, even there are organic ones synthesized. Well, some xenon compounds are very unusual but I have no idea how to attach it to the aromatic ring. And how is xenon related to halogens after all?
 
xenon is a halogen purely because of how it effects light(emitting a halo ((o)) effect). It's used in flood lamps and club/stadium lighting along with other halogen Krypton, argon.... Atleast that's MY understanding of the term
 
I just read a bit of an article about superatoms.

It seems a superatom made of 13 aluminum atoms can substitute to Br or I in every way... So I wonder if it would be possible to attach one of these into an aryl system?

Although, the resulting chemical would quite probably be too large to fit in the receptor... ;)
 
yeah 2C-Al13 what a dream ! But the superatom is too bulky to bind IMO... 2C-SE-2 and 7 are probably active compound as well as telluro analogue, but telluro compound are known as toxic and give garlic breathe. 2C-SF5 is the most interesting exotic 2C-X IMO because this group is more lipophile and bigger than the potent 2C-CF3...

2C-Xe can't exist because most existing xenon compounds are stable under -100 celcius... Example : XeO4 exploses at RT to give Xe and 2 O2...
 
seep said:
2cu.png


    
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Haha thats great.
 
MattPsy said:
Still not sure if i'm inferring the appropriate emotional content from the text (hell, even my own - everyone's autistic on the internet)
Click to expand...

Good point! I always have this paranoia too.

No actually I set out to try to counter what you had said and ended up figuring out you were right.

Anyway, the average N2O whippet contains 8 grams of N2O
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NSFW:
WhippetArt.jpg


It's 8 grams per charger; I'm not sure how much would need to reach the brain to achieve the desired effect, but it's certainly less than 8 grams. Consider:

  • 8 grams of N2O occupies 4 liters at STP.
  • The human body holds 5-6 liters of blood.
  • N2O's blood:gas partition coefficient is 0.47
  • N2O's brain:blood partition coefficient is 1.1

Maybe Dr. Riverhaven knows.
 
Yeah .... I wonder how much of a whippet actually ends up binding (or even just occupying) in the brain. Probably very little! That'd be really interesting to know, actually. I can't think of many other effective ways of measuring that other than making a radiolabelled N2O ... 18O would seem to be suitable. Haha, it's probably been done. Haven't looked quite yet.
 
(zonk) said:
xenon is a halogen purely because of how it effects light(emitting a halo ((o)) effect). It's used in flood lamps and club/stadium lighting along with other halogen Krypton, argon.... Atleast that's MY understanding of the term
Click to expand...

sorry i just have to fix the misunderstanding

fluorine, chlorine, bromine, iodine, and astatine are halogens. they have 7 electrons in their outer shell, so they are highly reactive and make a single bond in most compounds.

you are thinking of the noble gases (helium, neon, argon, krypton) which have a full valence shell and thus do not make bonds (except for Xe which can make exotic compounds like XeF4)

'halogen' has a VERY specific meaning in organic chemistry-- it refers to F, Cl, Br, and I.

'halogen' in lighting can mean anything really, generally an arc discharge lamp that may contain mercury, sodium, neon, or whatever.
 
greenmeanies said:
sorry i just have to fix the misunderstanding

fluorine, chlorine, bromine, iodine, and astatine are halogens. they have 7 electrons in their outer shell, so they are highly reactive and make a single bond in most compounds.

you are thinking of the noble gases (helium, neon, argon, krypton) which have a full valence shell and thus do not make bonds (except for Xe which can make exotic compounds like XeF4)

'halogen' has a VERY specific meaning in organic chemistry-- it refers to F, Cl, Br, and I.

'halogen' in lighting can mean anything really, generally an arc discharge lamp that may contain mercury, sodium, neon, or whatever.
Click to expand...

Indeed, Xenon is no halogen, lol. And they call this Advanced drug discussion, *sigh*
 
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