When somebody is clean after withdrawal, opioid antagonists can help to prevent relapse.
When all opioid receptors are antagonized, it is impossible for opioids like heroin to dock on. Then you can take heroin and nothing happens.
They have to use naltrexone because naloxone (which is most often used when somebody has an opioid overdose) doesn't have a long enough half life. Naltrexone works the whole day while naloxon is only good for half an hour or so...
It is possible to take naltrexone every day. But when somebody wants to use opioids, it would be no problem not to take naltrexone that day. So those implants are better. But actually I read stories where addicts teared those implants off their skin. But I'm not sure if that's true or an urban legend.
Naltrexone does not only block the effects of opioids. It is also said to reduce cravigs. So - if somebody has such an implant - it is also said to reduce heroin cravings.
And the reductions of cravings shall work for alcoholics, too.
In an other internet forum, I read that it should be great for the time after the acute withdrawal. Maybe it is good for PAWS because it reduces cravings. But maybe it also helps to lift your mood and works against depression and anxiety.
There is a new treatment being used for a variety of purposes using low dose naltrexone. It is well known that low dose naltrexone (LDN) increases endogenous endorphin levels 200 to 300%.
And those "low doses" of naltrexone are maybe so low that is not triggering withdrawal symptoms in opiate addicts.
In theory the low dose naltrexone does not block the opiate receptors significantly as the higher standard dose of 50 mg. Interesting ldn is even being used for constipation related to opioid use.
Has anybody tried it? How was it? I once injected naloxone. That was some kind of accident... Not funny! Instant cold turkey. All withdrawal symptoms immediately at 100%. Had to decide if I rather want to wipe up vomit or diarrhea. Luckily it got better after half an hour.
It would be interessting if naloxone could help with withdrawal symptoms or with cravings.
I would be glad if someone could post an experience report.