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  • BDD Moderators: Keif’ Richards

8 ball kinda?

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well i just crushed up a concerta(alza 27, alot of work)and some seroquel 400 and mixed the two to fine powder very fine powder haha and wondering what my effects are going to be? i know some people think its stupid to snort seroquel but to me it hits me so much harder and it feels like a xanax to me i don't know why but it does im really sensitive to the medication. One 400 mg pill can last me 2 weeks and i would get high off it every day, and the methylphenidate hits me hard when i snort it so i think this is going to be a good high 8 ball kind of thing. any thoughts?

Personal opinion of quetiapine (seroquel) aside, this is a pointless combination from a pharmacological standpoint.

Methylphenidate (concerta) exerts it's psychoactive effect by inhibiting the reuptake of dopamine (and norepinephrine) out of the synaptic cleft (the area where neurotransmitters activate chemical receptors). This results in abnormally high amounts of dopamine and norepinephrine activating their respective receptors. The increased action of dopamine is thought to be primarily responsible for the sought after effects (including euphoria), while the increased action of norepinephrine is believed to cause unwanted side effects (jitteryness, fast heartrate etc.).

Quetiapine belongs to a class of drugs called neuroleptics, or anti-psychotics. These drugs act primarily as 'dopamine antagonists' (quetiapine has other actions as well, but I won't go into that now). what that means is the drug binds to dopamine receptors in the synapse, but does not activate them. If a quetiapine molecule is already bound to a dopamine receptor, dopamine itself cannot bind and stimulate that receptor. Thus, the affect of dopamine is essentially blocked by this type of drug.

Therefore, quetiapine will work against the desirable effects of methylphenidate, and vice versa.
 
omfg... if ever there was a post that validates the need for bluelight and harm reduction, this is it.
ok, now i gotta clean the coffee that spewed out my nose off my monitor, keyboard, desk, etc, etc...
-izzy
 
i guess you all cant handle extreame sedatation cause i snorted a 400 mg pill and i was not out i swear on the bible you all are probably 40 year old virgins that sit home play video games all day and watch porn 24/7 fuck off dick heads.
 
No moron, we just like real drugs with recreational value. As I have previously stated you are most likely a 13 year old kid looking through mommies medicine cabinet. Why do you post here? You don't offer anything, and certainly not in the spirit of harm reduction. There are plenty of other websites with idiot kids such as yourself who would try to get high on a piece of bubble gum they found on the sidewalk.

I watch tons of porn for the record. LOL No shame here.
 
i guess you all cant handle extreame sedatation cause i snorted a 400 mg pill and i was not out i swear on the bible you all are probably 40 year old virgins that sit home play video games all day and watch porn 24/7 fuck off dick heads.

Trust me, all of that 400mgs did not absorb.
If you took it orally, different story.

You should fuck off from this website.
You ridiculously try to flame anyone who has proved you wrong.

You will clearly have no high and a really bad cause of side effects from this CRASH DUMMY combination.
 
Trust me, all of that 400mgs did not absorb.
If you took it orally, different story.

You should fuck off from this website.
You ridiculously try to flame anyone who has proved you wrong.

You will clearly have no high and a really bad cause of side effects from this CRASH DUMMY combination.

Just because you find facts from the government dosent mean there right and i first got into this drug when i was locked up like the one guy above me so how bout you fuck off this sight.
 
Just because you find facts from the government dosent mean there right and i first got into this drug when i was locked up like the one guy above me so how bout you fuck off this sight.

I'm talking about all the binders and fillers you are snorting.
They can block the absorption of drugs in pill form from completely absorbing.
The government had nothing to do with your ignorance.
Stop insulting them.
 
shipmentoffail.jpg
 
no alpraz, its fucking very funny, so funny i almost pissed myself (at least its that funny if you arent retarded and use the context of this thread)
 
This kid is some 14 to 15 year old who loves to come on the internet and pick fights, which is just like being in the special Olympics. Which in the end, even if you win, you are still fucking retarded. He has never had a useful or informational post and attempts to pick a fight with anyone who shows the facts about his misconceived and irrational belief on drugs, even though he claims to be very informed on the drugs he does. I am in favor or starting an effort to ban him from bluelight. Does anyone else agree?
 
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hey guess what sub. your opinion dosen't mater to anyone your a loser who needs to get a life and stop thinking I'm sum 14-15 year old kid I'm 18 but I'm a fun person to be around, probably unlike you cause your probably some hermit who sits in all day and does drugs by him self.(no offence to anyone else). you my friend need to shut up and go annoy someone else ya digg? ight, peace bitch.
 
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