• N&PD Moderators: Skorpio

Dimethocaine

Care to elaborate any more on duration and potency/effects? You're the only person I've read about using it and I have some on the way. Thanks!

I did see the other thread where you mentioned them being so similar in 3D.
 
I tryed The dimethocaine recently. I used doses from 25 to 75mg at once and 150mg over two hours. I didn´t notice any effects, maybe a litle bit but could be placebo. Even the local anestetic effect was not very strong. I have a high tollerance to stimulants but i have a stronger effect from 30mg methlyphenidat.
The supplier is known as very reliable.
 
Considering that most of the cocaine out there has lidocaine added, this problem substantially more dangerous than street coke.

'than'? I'd think how common lidocaine is added, those with experience with street cocaine needn't worry about the 1/4th potency of dimethocaine but equal anesthetic strength, as many have likely dealt with that with "coke" itself I'm assuming?
 
Yeah, but I think it's more like 50% potency

But is it 50% potency of 100% pure cocaine or cocaine that you normally get? I'm still awaiting my order. I don't know enough about cocaine to know what % what I've had was, but I would guess that it has been stepped on enough times by the time it gets to me that it's 50% or less pure.
 
Do you think many researchers buy their coke on the street?

I mean, for study that is. I dunno about personal use ;)
 
That seems crazy high. I never had any tolerance though, if that may be an issue.
 
That seems crazy high. I never had any tolerance though, if that may be an issue.

Last time i had coke it was probably 3 or 4 years ago, definitely not tolerance. Unless tolerance doesnt go down over time.

However i do seem to need more of most chemicals than the average person.
 
Got 2 grams today. tried 70mg nasally, followed by 50mg more after 30 mins. and it pretty nice. Subtle like coke, but definately gives you some euphoria, stimulation and confidence.

Duration seems to be 1-1½ hour. Not really a big in anaesthetic action IMO.
 
I received today as well. 100mg seems to be a good dose with a duration of an hour to an hour and a half. I agree with Repulse. Very similar in effects to cocaine.
 
Okay good, I thought I was crazy for a bit when I heard 300mg being called a starter dose!
 
I got 1g of it today, gonna give it a test run soon. Anyone recommend a good starting dose? Its 98+% Pure Dimethocaine. Is intranasal the best route? or can I take it oral as well?
 
After trying a few doses my notes on effect/dose/duration are as follows:

First/attack dose should be 100-200mg in bumps, taken over a short period of time (~15-20 mins) duration is 1½-2 hours for me and very coke like, but its not as potent, perhaps 50% potency of pure cocaine. Redoses can be done in 50mg bumps 1 hr at a time, that gives me the best effect atleast.

Its a nice pure alternative to coke, but don't expect an MDMAish high, or something like meth. If you have reasonably pure cocaine available at a reasonable price, it'd probably beat dimethocaine (with its current pricing) but i'm sure the price and availability on dimethocaine or other interesting analogs will be better before long..
 
I have some stupid questions about cocaine and the dimethocaine.
I have nearly no cocaine experience, its more than 10 years ago and i can barely remember it.

Doesen´t cocaine and dimethocaine have a strong anestetic effect on your tongue if you taste a litle bit on your finger (like in the movies)? Is it normal that i have only a litle anestetic effect and a strong chemical taste from the dimethacaine?

Is it normal that i get stronger effects from 30mg oral methylphenidat than from 100mg nasal dmc?
I think i feel some effect from the DMC on my heart but not on my brain.Is there somthing wrong with my bodys response to that chem, is 100mg to less for a the treshold effect?
I thought that it should have a stronger DA reuptake inhibiting effect than the MPH?
(i guess i have the same batch as the others have)
 
Methylphendidate is pretty strong, but 100mg of the DMCaine should produce effects, but everyone's brain is different.
 
Can we have some discussion on the metabolism of dimethocaine? If, as Hammilton mentioned, the ester is cleaved via pseduocholinesterase, PABA and 3-(diethylamino)-2,2-dimethylpropan-1-ol would be the expected products.

So then, are there any forseeable problems that could arise from repeated dosing and/or regular daily use? PABA, when taken as a supplement (for those without pseudocholinesterase deficiency) is recommended at ~400mg max/ day. However, having known a few coacaine users over the years, it's quite conceivable this level might be exceeded if dimethocaine was used as a replacement.

If the second metabolite is 3-(diethylamino)-2,2-dimethylpropan-1-ol, what sort of side effects could result high dosage use? Would it be excreted fast enough to avoid issues of toxicity? I believe there's been some research done on it as a possible anticancer agent, although from PubChem it appears it was inactive in all assays. The anion is also found as an ester in Syntropan (a parasympatholytic).
 
Does anyone know if Syntropan has stimulant activity?

I would be much happier if the para-desamino (??) version was being sold than plain old dimethocaine. I would be amazed if it wasn't more potent than dimethocaine by a lot.
 
I tryed The dimethocaine recently. I used doses from 25 to 75mg at once and 150mg over two hours. I didn´t notice any effects, maybe a litle bit but could be placebo. Even the local anestetic effect was not very strong. I have a high tollerance to stimulants but i have a stronger effect from 30mg methlyphenidat.
The supplier is known as very reliable.

that's quite a dissapointment. kinda like 4-f-cocaine..i had my hopes up for a good cocaine rc to hit the market..
 
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