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The Big and Dandy Ketamine Thread (Next iteration)

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Pretreatment of rat and rabbit with phenobarbital, an inducer of the CYP2B subfamily, causes a marked increase in the rate of ketamine metabolism...
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Involvement of CYP2B6 in N-Demethylation of Ketamine in Human Liver Microsomes
Yoshitsugu Yanagihara, Satoru Kariya, Michiteru Ohtani, Katsuyoshi Uchino, Takao Aoyama, Yoshikazu Yamamura, and Tatsuji Iga
Drug Metab. Dispos., Jun 2001; 29: 887.

Also, I can't find it right now, but I think R(-) ketamine or norketamine inhibits the metabolism of ketamine.
edit: Yup,
These results demonstrate that R(-)-ketamine inhibits the elimination of S(+)-ketamine.
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Stereoselective pharmacokinetics of ketamine: R(-)-Ketamine inhibits the elimination of S(+)-ketamine
Harald Ihmsen PhD, Gerd Geisslinger MD, PhD and Jürgen Schüttler MD
Clinical Pharmacology & Therapeutics (2001) 70, 431–438
 
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Sturnam said:
^ if you're looking for a place to share stories with ketamine addicts, TDS is probably the place to go.

but, have you noticed any urinary problems at all? either during use or after stopping?
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Hmmmm, no urinary problems since early 2007. The reason for it was because I was snorting about a gram a day, consistently.... for about 2 months. So this was prior to ever doing IV's, but at the start of IM doses. After 2 months I started to snort just half a gram a day and injected the other half in IM's, about 40-50mg/hr for the next 4 months.

At one point I had to pee every 15 minutes.... I found it hard to drive far and I peed in the back of a church because it was the only place where I turned off the freeway. Everything but this church was OPEN FIELD. I'm not trying to make a joke here 8)

I also had to stick a towel down my pants one time and pee in it because I was stuck in traffic on the 91 freeway (anyone from So. California will tell you that freeway is a bitch). This was when I was having to pee every 15 minutes.
Both these were from urinary infections from K.

Somewhere within this 6 month straight-through binge I ended up in the hospital because the pain in my stomach was so horrendous I couldn't get out of a fetus position the pain was too much. All the snorting/drips was eating my stomach apparently. This is why I started to move from snorting less to just doing IMs and snorting occasionally.

Since I only IM/IV now and don't snort K, I never have urinary problems.

Elemya
 
^ As far as I know the K-pains (the pain in your stomach area) and the urinary troubles (weird that in your case you had to pee too much..) are not just from snorting.

One of my friends was a full time IM'er of K, usually 120-150mg per shot, and he still got the K-pains.

I think the pain and urinary problems are due from the action of ketamine itself, or one of its metabolites.
 
ketamine question

My friend got ketamine no sources no matter how vague. It came in large crystals the size of table salt that were mixed with smaller crystals and powder. He crushed the k into powder and snorted it. It was the most painful thing he had ever snorted. It caused him to have the worst nose bleeds he had ever had. He let his friends try it and they agreed it was the worst thing they had ever snorted and nobody wants to do any more of it

Should he recook it? How would he do it? Is there something else he can do to it to make it less harsh and more soft on the nose?

He has snorted ketamine cooked by his friends many times in the past and the crystals were small and light and soft and fluffy. It was not at all similiar in look or consistancy to his current k and was not panful at all when snorted even in large amounts
 
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My friend got ketamineno source discussion. It came in large crystals the size of table salt that were mixed with smaller crystals and powder. He crushed the k into powder and snorted it. It was the most painful thing he had ever snorted. It caused him to have the worst nose bleeds he had ever had. He let his friends try it and they agreed it was the worst thing they had ever snorted and nobody wants to do any more of it

Should he recook it? How would he do it? Is there something else he can do to it to make it less harsh and more soft on the nose?

He has snorted ketamine cooked by his friends many times in the past and the crystals were small and light and soft and fluffy. It was not at all similiar in look or consistancy to his current k and was not panful at all when snorted even in large amounts
 
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A credit card or razor blade will not work.. your not working with powder.. but with crystals.

Grind it.

You need to crush and twist using the bottom of a bottle on a nor poroous surface. This cant be dont too much. Im thinking it's Ketajet cooked at a very high temp and probably microwaved.

But, maybe Im wrong.

We used to just syringe it onto a plate.. and let it sit there for about an hour and let it dry. Takes too much time, so people speed up processes by doing stupid things.
 
He has crushed it into as fine a powder as he can but he still finds it unbearable to snort.

Could it be mixed in a saline solution and squirted up the nose?
 
rkline said:
He has crushed it into as fine a powder as he can but he still finds it unbearable to snort.

Could it be mixed in a saline solution and squirted up the nose?
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I wouldnt use Saline since it contains the salt.

You could old-school it and add a little baking soda to it .. have to snort more.. but less crystals scraping the nasal cavities.
 
I have always found K to be very painful on the nose... but once you get a nice buzz going you stop feeling it and can go in for more without it hurting. I have gotten bloody noses from K, thats usually when I stop snorting lol.

But yes, all of the above suggestions are good too :)
 
fastandbulbous said:
^ Think it has to do with the lags in relaying senory info too the concious mind, so that unconciously you're aware somebody has moved so when it reaches the concious level you get the 'a-ha' deja vu feeling
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Hey! That`s pretty good! when ever me and my girlfriend do K(beats me if it`s the R or S isomer) i often feel like we can read each others minds. But your theory makes sense. Hats off to you!
 
rkline said:
My friend got ketamine from online. It came in large crystals the size of table salt that were mixed with smaller crystals and powder. He crushed the k into powder and snorted it. It was the most painful thing he had ever snorted. It caused him to have the worst nose bleeds he had ever had. He let his friends try it and they agreed it was the worst thing they had ever snorted and nobody wants to do any more of it

Should he recook it? How would he do it? Is there something else he can do to it to make it less harsh and more soft on the nose?

He has snorted ketamine cooked by his friends many times in the past and the crystals were small and light and soft and fluffy. It was not at all similiar in look or consistancy to his current k and was not panful at all when snorted even in large amounts
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Whatever he has isn't ketamine, even if it contains some ketamine.
 
I'm pretty sure its pure ketamine some of the crystals are just larger and circular like grains of salt. the high is normal, but snorting it is neary intolarable. any other ideas?
 
crush it finer so its actually a powder? I've had pure ketamine sting and hurt a little bit before, but nothing unbearable at all. maybe they just have really sensitive sinuses?
 
I get crystals that are like little glass shards.....pretty big for k I'd say8o But alas, it is ketamine :)

Ready......


Get a plate....put a gram or whatever on there, pour some water on it, just enough to dissolve it and stir.

Microwave it until you hear it pop and fizzle and subside....you'll know when.

Check it, if it's still wet, put it back in for a few seconds, if dry (HOT!!) then scrape that shit up and no more hard crystals :)

I had a Halloween party once, I had green and orange k on the plates...just a drop of food coloring. Funny to blow your nose and see colors though....red was fun haha. Also you can flavor your k.....just be creative.
 
stagger the load up the nose and divide it between the two nostrils helps too

sounds like you might have cut ketamine though :\

why somebody would cut ketamine is beyond me though. You can get that shit for 12 bucks a gram if you buy bulk...there is no need to cut when you can easily charge 40 bucks a gram.
 
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