Random DXM questions: The Higher Ground

[Newmoonrecord]

In lite of a recent epidemic of DXM questions we would like to make a place to send them off to once the question has been answered if it is not a pertinent enough question to make it into the Big and Dandy thread. - Karma1485


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Original post by Newmoonrecord:

Ok this is a really crazy question and i dont expect many answers, but i figured BL would be the best place to find somebody with experience with such rare circumstances.

So according to some studies, MAO-B enzyme turnover time (the amount of time it takes for brain mao-b enzyme to be synthesized) is approximately 30-40 days (half life).

I have waited 4 weeks since taking two one time doses of 2.5mg of selegiline (and approximately 9 weeks since being on it full time).

I'm looking to take dxm tonight or this weekend because i am getting impatient.

The dxm experience will obviously be a bit different with having increased dopamine given that nearly half of the previously inhibited mao-b is still inhibited. However.. it is unlikely that anywhere near 100% of my mao-b was actually inhibited 4 weeks ago, since the two one time doses seem on the low side to cause 100% inhibition.. Thus... a dramatic rise in dopamine is not necesarily to be expected, given that it has been 9 weeks since full mao-b inhibition.

I believe the trip itself will be safe and more or less harmless, as i have a few anecdotal reports of dxm use 2-3 weeks following a long term sustained selegiline use without any problems except moderate overstimulation.

Will having more dopaminergic activity during dxm use overwhelm the dissociative effects and lead to a more psychotic trip or will it more likely just keep me awake longer?? I usually pass out near or after the peak due to feeling super tired.. Which is nice... however, I wouldnt mind staying awake for a few extra hours, however i do not want to experiecne any temporary psychosis or being unable to sleep the whole night.

Am i going to be okay taking one bottle tonight? I know people who take DRI's (coke or methylphenidate) with dxm and do not experience problems, so I think i should be totally safe, but i just dont want the experience to be frantic, manic, or semi-psychotic.

Let me know what you think, and sorry if this post is not understandable as I am typing it in a hurry.

PS i have xanax and dopamine antagonists on hand.

Thanks!!

 

[*Love*Lite*]

Am i going to be okay taking one bottle tonight? I know people who take DRI's (coke or methylphenidate) with dxm and do not experience problems, so I think i should be totally safe, but i just dont want the experience to be frantic, manic, or semi-psychotic.

Very sorry Newmoon but no one can tell you if you will be safe consuming one bottle. DXM can be fatal at high enough doses. Make sure that you consult erowid on DMX before you dive in. Also mixing xanax with DXM may be something you want to consider NOT doing as well.

And to quote Erowid

Every individual reacts differently to every chemical.
Know your Body - Know your Mind - Know your Substance - Know your Source.

 

[delsymfan]

Really thought Newmoon, the issue is how much to your weight are you taking?

What kind of dosage are we talking here.

I believe you are pretty far off of your MAOI meds that you will be ok in that regard. I also believe there is more risk with MAO-A Is.

I have had a friend take Xanax and DXM and found it more relaxing but I do not have accurate dosage information.

I find I cant fall asleep on DXM unless I take a zolpidem (ambien).

Give us an idea of your dosage

 

[colors]

Will having more dopaminergic activity during dxm use overwhelm the dissociative effects and lead to a more psychotic trip or will it more likely just keep me awake longer?? I usually pass out near or after the peak due to feeling super tired.. Which is nice... however, I wouldnt mind staying awake for a few extra hours, however i do not want to experiecne any temporary psychosis or being unable to sleep the whole night. I know people who take DRI's (coke or methylphenidate) with dxm and do not experience problems.

i tripped on DXM with my gf while she was on a daily dose of Bupropion and she got really lethargic. she slept for a long time - i think it was about 3 days before she left the house. so as far as manic or psychotic, i didn't see it. you have other anecdotal info on that aspect too, so you can probably rule out that potential prob. good luck!

edit:
i have also used clonazepam and DXM simultaneously with no probs.

 

[Newmoonrecord]

i tripped on DXM with my gf while she was on a daily dose of Bupropion and she got really lethargic. she slept for a long time - i think it was about 3 days before she left the house. so as far as manic or psychotic, i didn't see it. you have other anecdotal info on that aspect too, so you can probably rule out that potential prob. good luck!

edit:
i have also used clonazepam and DXM simultaneously with no probs.

thanks for the info. Yes to the previous poster- the MAO-A inhibition is what would cause dxm to be more dangerous in regards to serotonin syndrome, but my mao-a is presumably fully functional.

I wasnt really asking if it was safe, i was asking if it would be weird as hell. I think my dose would be around 350mg, and i weigh 190lbs. By no means a large dose. I just dont want things to get weird.

 

[delsymfan]

See I dont think that dose would cause much in the way of shenanigans. You're looking at what 4mg/kg?

You'll probably have a bit of an altered trip, but idk.

Since MAOI + DXM is discouraged you likely wont find a ton of reports sad to say.

 

[Newmoonrecord]

See I dont think that dose would cause much in the way of shenanigans. You're looking at what 4mg/kg?

You'll probably have a bit of an altered trip, but idk.

Since MAOI + DXM is discouraged you likely wont find a ton of reports sad to say.

yes it is sad, there is a distinct lack of information about maoi combinations out there. It's probably for the best that people dont mess with them, but the new generation of maoi's are way safer and more useful than the ones the old scare mongering was directed towrds. I think i may wait another week or two just to be safe, as dxm felt really weird to me when i tried it (200mg) on small doses of mph.

 

[delsymfan]

Serious thoughts while on DXM

Im posting this because I find my mind looks at serious issues very very differently while on DXM. I'm curious if others find the same altered state of view.

To kind of explain this is hard but I'll try...

Sometimes to me, life just doesnt feel 100% real. Like almost as if were characters in a movie. It just seems surreal to me once in a while.

And on DXM, it feels like everything I know of IS real to the fullest extent possible.

And as a result I think I take serious things more seriously.

For instance I was Dexed up and my friend was drinking. I was kinda in my own zone and he passed out. I saw him laying there and my mind was thinking about death.

Death on DXM was viewed as ultimate finality. And it was hard to explain, but never before have I felt how REAL death is. How powerful it was. How permanent.

And on another occasion. Myself and same friend were watching TV. A commercial for protection against STD's came up. I was Dexed up and got to thinking "Its amazing to think STDs are REAL and how serious they are"

I might not be making any sense. But I guess to me, DXM kind of sobers your mind up to some of the harsher realities of life. I have to say though, I seem to take those things more seriously now which could be a good thing.

 

[helium-4]

Congrats you had an introspective experience. Psychedelics alter your perception, get used to it.

 

[nearjat]

The first thing you mentioned sounds a lot like dissociative induced depersonalization disorder. I had DPD "attacks" for about two weeks after a 3rd plateau trip, very scary.

 

[dexingpotsmoker]

I think the effects of DXM just vary widely from person to person. I never felt anything remotely like what you said. If anything when I dexed it was to make life my own cartoon. To turn it into whatever I wanted, but not reality by any means.

I did DXM habitually for two years, and daily for one.

Different things affect people differently is all.

 

[dexingpotsmoker]

yeah that's a really in depth question, afraid I can't help you.

The only part I have experience in is mixing it with Methylnphenidate, which does produce a pretty uppity psychotic high. If what you're talking about is anything like that, you should be awake for quite some time and feeling odd as hell.

 

[Excido]

After a stint of DXM abuse, I got to the point where when I took DXM I would go into these crazy serious/deep introspective thought patterns, usually focused around death and the true largeness of the universe and resulting insignificance of humans particularly myself etc etc. It was both a bad thing and a good thing, I feel more aware yet feel more insignificant like nothing we do really matters.

 

[delsymfan]

Yeah Excido you sound pretty much where I'm at with this...

For the record there has not been any DPD. You may be misunderstanding things a little.

And I'd say it wasnt so much introspective. I've only had one profound "look" into myself and that produced some great thoughts.

But yeah it just seems like I have thoughts similar to that of Excido.

Not a bad thing by any means, just curious to see how others respond.

 

[nearjat]

How the hell do you remember anything significant from your DXM trips?

My trips went like:

1. Dose
2. I'm itchy
3. lol
4. durrrr
rrrrrrrrr
rrrrrrrrr
rrrrrrrrr
rrrrrrrrr
5. zZzZzZzZ
6. *yawn*
7. go through my day feeling really fucked up and nasty.

I remember having some significant thoughts that had great meaning to me, but I don't remember what the hell they were!

 

[delsymfan]

Lol man my trips are so clear and so awesome...

First of all, I'm immune to the robo itch thank god. That wrecked my friend one night. However a small dose of benadryl seems to aleviate symptoms.

Come up takes a while and I just relax. Eventually I kill most lighting and just leave my ipod on. Keep a tiny bit of dim light in the room.

I'll sometimes float off with open eye weirdness. Like I will look at the ceiling, and it will feel like I'm moving. As if I'm on a gurney or stretcher. And then I just let that take me wherever.

I get some really deep CEVs sometimes. Like one time I delved into the TRON universe and fixed their central computer.


Next day I feel clean, bright, and happy. I find I'm way nicer and more likely to buy somebody something, or talk to random people at work.

 

[Newmoonrecord]

Yes. This is why i use dxm. On low doses at least (high doses have me near passing out on my bed and I dont have many thoughts). I usually read articles about sci fi stuff, or space travel, or like, the economy, state of the world, "big thinking" type stuff. It all seems so grand. And i get this feeling like i am just taking in all this special knowledge and that everything in the world is so interconnected. It usually continues with me for a few days, which is nice, but eventually I just go back to my mundane everyday existence. Then it's time for dxm again!

 

[delsymfan]

NMR you put it nicely...

Now for me, any dose under 4mg/kg is pretty much all Recreational. I cant really delve into things mentally speaking. I just get a great buzz and feel loose and wanna dance/party.

Around 4-7mg/kg is where I'd hit that more interesting level. However around 6 makes it highly difficult to read the internet and use a keyboard.

But yeah it really helps me just realize how much there is out there and how miniscule we are in comparison. And it puts everything into a different perspective.

I feel I've taken a LOT out of my DXM trips and thats why I keep doing em!

 

[nearjat]

NMR you put it nicely...

Now for me, any dose under 4mg/kg is pretty much all Recreational. I cant really delve into things mentally speaking. I just get a great buzz and feel loose and wanna dance/party.

Around 4-7mg/kg is where I'd hit that more interesting level. However around 6 makes it highly difficult to read the internet and use a keyboard.

But yeah it really helps me just realize how much there is out there and how miniscule we are in comparison. And it puts everything into a different perspective.

I feel I've taken a LOT out of my DXM trips and thats why I keep doing em!

If I could get/extract pure DXM HBr powder before dosing, in an interesting setting, and get rid of Olneys Lesions, I'd be lovin that DXM. I'm very high right now, and just had some strange delusion that there were DXM containing herbs and shit. Yeah . MDMA (possibly some RC MAYBE, very possible I just have a psychedelic reaction to MDMA, I do with chems that many don't.

 

[Newmoonrecord]

If I could get/extract pure DXM HBr powder before dosing, in an interesting setting, and get rid of Olneys Lesions, I'd be lovin that DXM. I'm very high right now, and just had some strange delusion that there were DXM containing herbs and shit. Yeah . MDMA (possibly some RC MAYBE, very possible I just have a psychedelic reaction to MDMA, I do with chems that many don't.

you have olney's lesions? did they find them on a medical scan? to my knowledge there is no medical evidence that olneys lesions appear following oral dxm use in any test subjects.