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Coming off Invega/Xeplion (paliperidone) injections v 12

taoyin said:
I heard the 3‑month paliperidone injection can stay in the body for up to 18 months. Can you check my paliperidone blood level abroad? Please look into it / please check whether it can be done.
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User rawbanana got one in v11 of the thread before he took his life, but he was on Sustenna (1 month), not Trinza. Hopefully this is useful to you:

Has anyone here gotten a paliperidone blood level test? I got mine and it’s 1 ng/mL after 9+ months off the injection.
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https://www.bluelight.org/community...iperidone-injections-v11.949384/post-16333006

Labcorp and Quest both have the test. You just need to get your doctor to write a slip and you can take it to Labcorp if you are in the United States. I’m not sure how it works anywhere else.
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https://www.bluelight.org/community...iperidone-injections-v11.949384/post-16330586

There was a study with a man with a bmi of 36 who got Invega shots for 4 months and 19 months later his blood levels were around 1.5ng/ml which is still enough to cause an effect.
This is the study https://journals.lww.com/psychophar...ged_elimination_of_paliperidone_after.21.aspx
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https://www.bluelight.org/community...iperidone-injections-v11.949384/post-16329631
 
invega-survivor101 said:
I have been off invega trinza since Feb 13 2024 its now February 26 2026 2 years and 2 weeks I still feel emotionally numb no feelings no libido when I Masterbate I feel nothing inside my head no pleasure what's so ever when I listen to music it just sounds w.e to me no joy from it or interest i still have no libido my testosterone is still low I have no confidence I want to go back to my old self before invega its been over .2 years and I only had 1 shot of invega trinza why haven't I recovered yet? Has anyone else tooken invega trinza and still not back to normal past 2 years? How much longer do I have to go through this till I'm normal again feeling emotions and all that no matter what I do I get no pleasure or head rush I feel the same mood 24 7 and feel numb no excitement no emotions no feeling happy or sad or laughing just flat who else has taken invegs trinza before and has recovered ? Or still hasn't recovered and its been over 2 years I waa drinking alot last year I heard alcohol delays recovery and puts it back longer from healing I have been sober from alcohol for 53 days now and still no improvements no emotions no libido no joy of music no feelings how much longer will I take to heal and have dopamine again and serotonin or am I stuck like this forever when will I go back to my old self before invega its like I am not getting better as the days go by the weeks go by the months go by the years go by this is ridiculous who else can relate?
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I have many of the same symptoms as you, but I only received 3 shots of Sustenna and it has been about 6 months since the last shot. I can listen to music, but masturbation and sexual sensations still don't feel as they did before. However, I did regain the ability to laugh and feel sadness / anger.

It's good that you quit drinking alcohol, that can definitely prolong your recovery. But to be 100% honest, I haven't seen a Trinza recovery story myself.
Personally I think it is just a longer recovery period, but it's possible that we won't quite be 100% the same again, whether it was Sustenna or Trinza.

Some people here haven't recovered from Sustenna yet, but are still within a 2-3 year period since the last injection. I've rarely seen anyone still having issues after that length of time, but it's hard to know if everyone fully recovered or not.

If you are able to use cannabis/THC I recommend it, it's really helped me fall asleep at night and pass the time during the day. Unfortunately it can be expensive as a daily habit and I probably won't be able to keep using it for months continuously.
 
Never suicide life can be enormously blissful still, get therapy cause forced drugging on falsely diagnosed mental ilness might be extremely traumatic especially if repeated, i need one... Not threats with Police and hospital toxic family :)
 
YogirisingKundalini said:
Never suicide life can be enormously blissful still, get therapy cause forced drugging on falsely diagnosed mental ilness might be extremely traumatic especially if repeated, i need one... Not threats with Police and hospital toxic family :)
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Why you say never suicide? My last injection (second dose) was June 6. Falsely Diagnosed. My life feels completely destroyed. I only think about dying but I don’t have the courage to end it. I want to gather enough medical treatments to request assisted dying through Dignitas, Pegasus or Athanasious. I pray to God he helps me leave this world soon even if he doesn’t want to give me heaven. If he could vanish my soul from existence that seems fair. But I didn’t ask for this life and I’m not asking for a better existence in another world or anything. I do want this pain to stop.
 
JSteban7 said:
Why you say never suicide? My last injection (second dose) was June 6. Falsely Diagnosed. My life feels completely destroyed. I only think about dying but I don’t have the courage to end it. I want to gather enough medical treatments to request assisted dying through Dignitas, Pegasus or Athanasious. I pray to God he helps me leave this world soon even if he doesn’t want to give me heaven. If he could vanish my soul from existence that seems fair. But I didn’t ask for this life and I’m not asking for a better existence in another world or anything. I do want this pain to stop.
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You'll be alright man, you had 1 less shot than I did and we both got them within a couple of months of each other.

Things should start getting better for you soon around the 4-5 month mark, as the elimination half-life of the drug seems to fall exactly within that window at 4.5 months:
https://www.ovid.com/jnls/psychopha...mination-of-paliperidone-after-administration (1.3 ng/mL paliperidone measured after 19 months)

Imo the reason it's taking so long to recover is because things look a lot different with a 4.5 month half-life as opposed to 49 days or whatever similar number people have been assuming.

Check my post history if you want to try out some supplements to see if it helps any. I've been taking them since July, figure it doesn't hurt to make sure my brain has whichever compounds it might need to recover and heal.

Exercise helps a lot too but it can be tough to force yourself to do it. This week wasn't so good for me and I mostly stayed home instead of going to the gym.
 
"I got two shots of Invega Sustenna within 7 days back in March. I still don't feel fully recovered. It feels like all the nerves in my body are being controlled, I can't cry and I'm not happy either. Weak erections, low testosterone. I can't fall asleep until around 1 AM every day. Then I got my blood Paliperidone level checked, it came back at 3.78. I suggest everyone go get your own blood Paliperidone level checked, so you don't have to doubt yourself all day. I'm a patient from China. I stopped the injections over 6 months ago."
JSteban7 said:
Did you recover? I’m in the same situation. I received two injections last one was June 6 and my life is ruined. I will do whatever for an assisted suicide.
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"I got two shots of Invega Sustenna within 7 days back in March. I still don't feel fully recovered. It feels like all the nerves in my body are being controlled, I can't cry and I'm not happy either. Weak erections, low testosterone. I can't fall asleep until around 1 AM every day. Then I got my blood Paliperidone level checked, it came back at 3.78. I suggest everyone go get your own blood Paliperidone level checked, so you don't have to doubt yourself all day. I'm a patient from China. I stopped the injections over 6 months ago."3.17 150
3.24 100
 
taoyin said:
“三月份的时候，我在七天内打了两针Invega Sustenna。到现在我还没完全恢复。感觉全身的神经都像被控制住了一样，哭不出来，也不开心。勃起功能障碍，睾酮水平低。每天要到凌晨一点左右才能睡着。后来我做了血液帕利哌酮水平检测，结果是3.78。我建议大家都去做一下血液帕利哌酮水平检测，这样就不用整天提心吊胆了。我来自中国，已经停针六个多月了。”
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只两针不会死的，但是要慢慢煎熬的，我还没完全康复，康复的话会跟你们说的，
 
taoyin said:
"I got two shots of Invega Sustenna within 7 days back in March. I still don't feel fully recovered. It feels like all the nerves in my body are being controlled, I can't cry and I'm not happy either. Weak erections, low testosterone. I can't fall asleep until around 1 AM every day. Then I got my blood Paliperidone level checked, it came back at 3.78. I suggest everyone go get your own blood Paliperidone level checked, so you don't have to doubt yourself all day. I'm a patient from China. I stopped the injections over 6 months ago."3.17 150
3.24 100
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I saw story of young man having anti government views in China and receiving schizophrenia diagnosis due to it and on raisedbynarcissist i saw people comparing such parents to dictators, every ego is the same ego huh
 
Has anyone spoken to or knows of anyone thats switched to aripriprizole and got some functioning back? It’s supposed to have a higher binding affinity to paliperidone meaning it can push the paliperidone off the receptors and allow for some dopamine to come through.. apparently but 7 months with an empty head and feeling completely disconnected has left me extremely desperate for anything that will allow even the slightest of dopamine through.. man I went three days without nocotine and the hit was just a body sensation no mind sensation whatso ever it’s really freaking me out but without the actual ability to freak out im desperate so desperate
 
blanch116 said:
Has anyone spoken to or knows of anyone thats switched to aripriprizole and got some functioning back? It’s supposed to have a higher binding affinity to paliperidone meaning it can push the paliperidone off the receptors and allow for some dopamine to come through.. apparently but 7 months with an empty head and feeling completely disconnected has left me extremely desperate for anything that will allow even the slightest of dopamine through.. man I went three days without nocotine and the hit was just a body sensation no mind sensation whatso ever it’s really freaking me out but without the actual ability to freak out im desperate so desperate
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I tried vraylar which does the same thing and got nothing unfortunately once you get invega killshot your dopamine receptors are fried no matter what but can’t hurt to try
 
invegaispain said:
I tried vraylar which does the same thing and got nothing unfortunately once you get invega killshot your dopamine receptors are fried no matter what but can’t hurt to try
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I’ve spoken to a few others that recovered and they’re still on some antipsychotic which baffles me, they all day around 17 months off which sucks arse meaning ive got another ten months of this shit and thats only a hope that things will improve there’s no actual definite which is scary.. bro I’ve ages ten years in the past 6 months it’s scary as hell
 
blanch116 said:
I’ve spoken to a few others that recovered and they’re still on some antipsychotic which baffles me, they all day around 17 months off which sucks arse meaning ive got another ten months of this shit and thats only a hope that things will improve there’s no actual definite which is scary.. bro I’ve ages ten years in the past 6 months it’s scary as hell
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There is a possibility where u cross the 24 months mark and being still disabled like me and other people inside here who basically stopped from posting
 
RisperdalConsta50mg2 said:
Same, the first thing i think when i see someone is to remember what being normal and not brain-damaged is.. It’s really depressing.
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How do I get free of this? I don't want this brain anymore. I can't live with this brain. I am a stranger to this brain. All I ever wanted was to be normal. Is suicide the only option?
 
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