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Gabapentinoids The Lyrica (Pregabalin) Mega Thread v 2.0

I took 600mg with hydroxyzine 100mg 10mg diazepam 8g kratom joints of black hash I am tripping well have a good one
 
I'll never get why people abuse these god awful pharamcuticals that dont provide much of high plus the long term consequences of it.
because they feel nice?

"don't provide much of a high" lol you've clearly never taken pregab then.

what long term consequences are you talking about specifically? plenty of the issues & risk are well known and understood....
But hey these youngings could careless if there in the old age home in their late 50s and 60s not remembering who their family is because its not happening now.
I'm in my 50s. Granted I've only been taking pregab for a couple of years, but I'm not some gung ho child eating any pill I can get my hands on without a care about the consequences.

where are the papers supporting pregab causing people to forget who their families are?

The perceived wisdom of studies I think is that the cognitive effects of abusing pregab is reduced/removed when the abuse stops, and that these effects are compounded by other substances especially benzos and opioids.

think the bigger issue for people with big abuse problems is that you may need pregab for a real condition at some point in life, though you could say that about a few things, opioids anyone?

please don't spread misinformation, I'm happy to be proven wrong, but proven is the key word, link some papers that back up what you're saying.
 
@KriptonitXxx 3,600 mg/day is the commonly prescribed max dosage, that has a bioavailability of about 30%, you're saturating your L-amino-acid transport system at some point and taking more won't do anything




Sorry but I'm not feeling it tbh.
Sounds like Luke Vibert gone wrong imho.

I'm one of those of Jungle guys when JUNGLE MEANT JUST THAT, Kids these days know fuck all.
Think Dead dred - Dred Bass on Moving Shadow records or Ray Kieth - Terrorist
 
I'll never get why people abuse these god awful pharamcuticals that dont provide much of high plus the long term consequences of it.
"don't provide much high"

Owkay you keep talking as I highly question you have ever taken them, Erowid says otherwise & this thread also says something else BUT to play to your viewpoint YMMV I guess.

god awful pharamcuticals
the "s" on the end makes it a plural meaning more than one, you want to speak about a drug at the least know the difference between a single & a plural as you look really stupid.

the long term consequences of it.
Take that up with people who have drank DXM / DXO for years, not people who take Pregabalin a few times a month, it's no worse than eating fruit that Monsanto have covered in their Chemical death, the lead from car fumes, Radioactive waste in the air from Nuclear tests, micro-plastic neurotoxic stuff in the food, water & air. Pick your battles carefully before you go to War I say.
But hey these youngings could careless if there in the old age home in their late 50s and 60s not remembering who their family is because its not happening now.
Taken way more drugs than you have, sniffed glue, solvent, injected Heroin with water I sucked up from a puddle in the street, smoked over 28 grams of MDPV Hcl etc & I am 45 & am fitter than you are & also way less stupid may I add.

FFS I sniffed Glue for ages & I still know what a Plural is, you can't say this as the evidence is clear to see.
 
because they feel nice?

"don't provide much of a high" lol you've clearly never taken pregab then.

what long term consequences are you talking about specifically? plenty of the issues & risk are well known and understood....

I'm in my 50s. Granted I've only been taking pregab for a couple of years, but I'm not some gung ho child eating any pill I can get my hands on without a care about the consequences.

where are the papers supporting pregab causing people to forget who their families are?

The perceived wisdom of studies I think is that the cognitive effects of abusing pregab is reduced/removed when the abuse stops, and that these effects are compounded by other substances especially benzos and opioids.

think the bigger issue for people with big abuse problems is that you may need pregab for a real condition at some point in life, though you could say that about a few things, opioids anyone?

please don't spread misinformation, I'm happy to be proven wrong, but proven is the key word, link some papers that back up what you're saying.
QFT
 
could careless if there in the old age home in their late 50s and 60s not remembering who their family is because its not happening now.
I'd be glad to be in a home by that age with no memory of my family as they are horrible.
Also the Council will pick up the bill 100% for my living costs so I can live with ZERO COST as some Nurse in her 20's who's from The Philippines comes to talk to me & washes my Dick, maybe if I slip the bitch a £20 she will suck me off too.

Ye Gods I will be cooking up 5,000mg of Pregabalin to I.V. if that is the case, I am off to get some 1ml needles right now.

Yeah the idiot didn't think the post through too well BEFORE they posted I feel.
b3f06b453f53424ee7cb1698e25e5899.jpg

"Aaaa Mr Zopi me love you MUCH LONG TIME, I bring you much good Medicine as I your top girl, good Diamorphine mix with Cartel Cocaine 90% pure, I be good girl yes?"

@placebonaut
;);););)
 
Last edited:
because they feel nice?

"don't provide much of a high" lol you've clearly never taken pregab then.

what long term consequences are you talking about specifically? plenty of the issues & risk are well known and understood....

I'm in my 50s. Granted I've only been taking pregab for a couple of years, but I'm not some gung ho child eating any pill I can get my hands on without a care about the consequences.

where are the papers supporting pregab causing people to forget who their families are?

The perceived wisdom of studies I think is that the cognitive effects of abusing pregab is reduced/removed when the abuse stops, and that these effects are compounded by other substances especially benzos and opioids.

think the bigger issue for people with big abuse problems is that you may need pregab for a real condition at some point in life, though you could say that about a few things, opioids anyone?

please don't spread misinformation, I'm happy to be proven wrong, but proven is the key word, link some papers that back up what you're saying.
I mean all drugs cause risks but the high versus the risk potential Dementia Risk down road its not worth it.
 
I mean all drugs cause risks but the high versus the risk potential Dementia Risk down road its not worth it.
so Pregab causes dementia now?!

wtf? why you would spout baseless claims that can be checked is beyond me, you do realise that people read this forum for information, scaremongering and providing false info is really fucking irresponsible.

so here you are, I got off my arse and did it for you

for anyone else reading, chatgpt summary but go and read the papers, they exist....
  1. You said: are there any studies about pregabalin and Dementia?​


  2. ChatGPT said:​

    Yes. There are studies on pregabalin and dementia, but the evidence is still fairly limited and it depends on what you mean by “pregabalin and dementia.”

    1. Pregabalin for behavioral symptoms in dementia​

    The most interesting recent study is a 2024 randomized, double-blind, placebo-controlled trial involving 53 people with mild-to-moderate Alzheimer’s dementia who had behavioral and psychological symptoms.

    Participants received pregabalin, titrated up to 300 mg/day, or placebo for 12 weeks. The pregabalin group had significantly greater improvements in overall neuropsychiatric symptoms and behavioral symptoms, including depression-related symptoms and caregiver burden.



    However, 53 participants is a small study, and it was only 12 weeks long. So it is promising, but it isn't enough to establish pregabalin as a standard dementia treatment.

    2. Pregabalin for agitation/aggression​

    There is also a 2019 systematic review specifically looking at gabapentin and pregabalin for agitation/aggression in dementia. At that time, the authors found 24 relevant publications, but only six patients had been treated with pregabalin in the case reports/series. They concluded that the evidence for pregabalin was very low quality because there weren't randomized trials.

    Interestingly, a 2024 case series of 10 dementia patients looked at gabapentin/pregabalin for agitation and reported potentially useful effects, but again this was observational evidence rather than a controlled trial.

    3. Does pregabalin increase the risk of developing dementia?​

    This is a different and important question.

    A large Taiwanese observational study involving 206,802 people found that people exposed to gabapentin or pregabalin had a higher subsequent incidence of dementia. The adjusted hazard ratio was 1.45 (95% CI 1.36–1.55).

    But this doesn't prove pregabalin causes dementia. The study combined gabapentin and pregabalin, and observational studies can be affected by confounding by indication: for example, people taking these drugs may already have pain, neurological problems, sleep problems, or other conditions associated with later dementia.

    4. What about memory and cognitive impairment?​

    This is where things get particularly interesting. Pregabalin can cause dizziness, somnolence, blurred vision and other CNS effects, and in an older person—especially someone with dementia—these effects can look like or worsen cognitive impairment, confusion, reduced alertness or falls.

    So there are really two separate questions:
    • Can pregabalin help dementia-related agitation/anxiety/behavioral symptoms? → There is some promising evidence, including a small randomized trial.
    • Can pregabalin cause or accelerate dementia/cognitive decline? → There is an observational signal that warrants caution, but it does not establish causation.
    If you're asking because someone with dementia is currently taking pregabalin, I can also look specifically at the evidence for pregabalin causing confusion, memory loss, cognitive decline, sedation or worsening dementia, including what happens after reducing/stopping it. That is a somewhat different body of evidence and may be more relevant.



  3. You said: has anyone reproduced or confirmed the Taiwanese study results? is the conclusion therefore that correlation does not equal causation?​


  4. ChatGPT said:​

    Yes — and I think your interpretation is basically right, with an important nuance.

    I looked specifically for replication of the 2023 Taiwanese finding rather than just studies showing that pregabalin can affect cognition.

    Has the Taiwanese result been replicated?​

    Not convincingly for pregabalin specifically, as far as I can find.

    The Taiwanese study was actually the first population-based cohort study specifically examining dementia risk from gabapentin/pregabalin, according to its authors. It combined the two drugs into one exposure group, rather than analyzing pregabalin alone. It found HR 1.45 (95% CI 1.36–1.55) for dementia.

    There is an important piece of evidence going in the other direction, though.

    A 2023 meta-analysis of observational studies of anti-seizure medications found no statistically significant association between pregabalin and dementia: pooled OR 0.84 (95% CI 0.64–1.11). Gabapentin was also not associated with increased dementia risk (OR 0.76, 95% CI 0.49–1.18).

    That isn't a perfect replication/non-replication test—the studies included in that meta-analysis aren't necessarily directly comparable to the Taiwanese cohort—but it certainly doesn't provide independent confirmation of a harmful pregabalin effect.

    There's also a newer observational study looking at gabapentin/pregabalin users in relation to kidney disease. Interestingly, in people without chronic kidney disease, gabapentin had essentially no difference in dementia risk compared with pregabalin (HR 1.09, 95% CI 0.89–1.34). That's not a test of pregabalin vs non-use, so it can't settle the question, but it illustrates how complicated these associations are.

    So, yes: correlation ≠ causation​

    More precisely, the Taiwanese study demonstrates:

    People who took gabapentin or pregabalin subsequently received diagnoses of dementia more often than matched people who didn't take them.
    It does not demonstrate:

    Taking pregabalin causes dementia.
    That's an important distinction.

    The Taiwanese researchers themselves acknowledge that their study was retrospective and say that prospective studies are needed to understand whether there is a causal mechanism.

    There are several possible explanations for their result:
    • Confounding by indication: people taking pregabalin may have conditions that themselves increase dementia risk.
    • Age/health differences: people prescribed pregabalin may have more neurological disease, chronic pain, sleep problems, anxiety, etc.
    • Reverse causation: very early cognitive/neurological changes could contribute to symptoms that lead to pregabalin being prescribed.
    • Detection bias: people taking medication regularly may have more healthcare contact and therefore more opportunities for dementia to be diagnosed.
    • Drug effect: it is also possible that pregabalin genuinely contributes to cognitive impairment or dementia risk. The observational study cannot exclude this.

    There's an especially interesting problem with the Taiwanese result​

    The dose-response finding initially sounds quite compelling: dementia risk increased with cumulative exposure, with the highest exposure category having HR 2.44 compared with the lowest.

    Normally, a dose-response relationship makes a causal hypothesis more interesting.

    But there is something odd: the association was stronger in people under 50 than in older people. The reported HR was 3.16 in people under 50 versus 1.30 in people ≥70.

    That's not what I would expect if pregabalin were simply accelerating the usual neurodegenerative dementias of old age. It doesn't disprove causality, but it makes me considerably more cautious about interpreting the association as "pregabalin causes Alzheimer's/dementia."

    My reading of the evidence​

    If we rank the conclusions by confidence:

    High confidence:
    Pregabalin can cause CNS effects such as sedation, dizziness and cognitive impairment in some people. That's quite different from proving that it causes neurodegenerative dementia.

    Moderate confidence:
    There is an observational association between gabapentinoid use and subsequent dementia diagnoses in the Taiwanese dataset.

    Low confidence:
    Pregabalin itself increases the long-term biological risk of developing dementia.

    Currently unsupported:
    That pregabalin causes Alzheimer's disease or accelerates the underlying neurodegenerative process.

    And importantly, I would not regard the Taiwanese paper as established evidence that pregabalin causes dementia. The lack of clear independent replication, the fact that gabapentin and pregabalin were pooled, and the observational design all matter.

    If your underlying question is "Could pregabalin make an existing person's dementia or memory problems worse, and could that improve if pregabalin is reduced/stopped?", that's actually a much more clinically answerable question. The evidence there is different from the dementia-incidence question, and I can dig into that specifically.





    TopicPaper
    Year​
    Link
    Dementia risk — Taiwan cohortHuang Y-H, Pan M-H, Yang H-I. The association between Gabapentin or Pregabalin use and the risk of dementia: an analysis of the National Health Insurance Research Database in Taiwan.
    2023​
    Dementia risk — systematic review/meta-analysisGabapentinoid Use and Risk of Alzheimer's Disease-Related Dementias: A Systematic Review and Meta-analysis of Observational Studies.
    2026​
    Dementia risk — gabapentin in chronic painTsai SE, Yang SF, Wang YH, Yeh CB. Association between gabapentin use and risk of dementia in adults with chronic pain: A nested case-control study.
    2024​
    Behavioral symptoms — systematic reviewGabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report.
    2019​
    Behavioral symptoms — randomized trialA randomized, double-blind, placebo-controlled clinical trial to evaluate pregabalin efficacy in the treatment of behavioral and psychological symptoms of dementia in patients with Alzheimer's disease.
    2024​
    Gabapentinoids in older adults — reviewBenefits and risks of gabapentinoids in geriatric psychiatry.
    2025​















 
so Pregab causes dementia now?!

wtf? why you would spout baseless claims that can be checked is beyond me, you do realise that people read this forum for information, scaremongering and providing false info is really fucking irresponsible.

so here you are, I got off my arse and did it for you

for anyone else reading, chatgpt summary but go and read the papers, they exist....
  1. You said: are there any studies about pregabalin and Dementia?​


  2. ChatGPT said:​

    Yes. There are studies on pregabalin and dementia, but the evidence is still fairly limited and it depends on what you mean by “pregabalin and dementia.”

    1. Pregabalin for behavioral symptoms in dementia​

    The most interesting recent study is a 2024 randomized, double-blind, placebo-controlled trial involving 53 people with mild-to-moderate Alzheimer’s dementia who had behavioral and psychological symptoms.

    Participants received pregabalin, titrated up to 300 mg/day, or placebo for 12 weeks. The pregabalin group had significantly greater improvements in overall neuropsychiatric symptoms and behavioral symptoms, including depression-related symptoms and caregiver burden.



    However, 53 participants is a small study, and it was only 12 weeks long. So it is promising, but it isn't enough to establish pregabalin as a standard dementia treatment.

    2. Pregabalin for agitation/aggression​

    There is also a 2019 systematic review specifically looking at gabapentin and pregabalin for agitation/aggression in dementia. At that time, the authors found 24 relevant publications, but only six patients had been treated with pregabalin in the case reports/series. They concluded that the evidence for pregabalin was very low quality because there weren't randomized trials.

    Interestingly, a 2024 case series of 10 dementia patients looked at gabapentin/pregabalin for agitation and reported potentially useful effects, but again this was observational evidence rather than a controlled trial.

    3. Does pregabalin increase the risk of developing dementia?​

    This is a different and important question.

    A large Taiwanese observational study involving 206,802 people found that people exposed to gabapentin or pregabalin had a higher subsequent incidence of dementia. The adjusted hazard ratio was 1.45 (95% CI 1.36–1.55).

    But this doesn't prove pregabalin causes dementia. The study combined gabapentin and pregabalin, and observational studies can be affected by confounding by indication: for example, people taking these drugs may already have pain, neurological problems, sleep problems, or other conditions associated with later dementia.

    4. What about memory and cognitive impairment?​

    This is where things get particularly interesting. Pregabalin can cause dizziness, somnolence, blurred vision and other CNS effects, and in an older person—especially someone with dementia—these effects can look like or worsen cognitive impairment, confusion, reduced alertness or falls.

    So there are really two separate questions:
    • Can pregabalin help dementia-related agitation/anxiety/behavioral symptoms? → There is some promising evidence, including a small randomized trial.
    • Can pregabalin cause or accelerate dementia/cognitive decline? → There is an observational signal that warrants caution, but it does not establish causation.
    If you're asking because someone with dementia is currently taking pregabalin, I can also look specifically at the evidence for pregabalin causing confusion, memory loss, cognitive decline, sedation or worsening dementia, including what happens after reducing/stopping it. That is a somewhat different body of evidence and may be more relevant.



  3. You said: has anyone reproduced or confirmed the Taiwanese study results? is the conclusion therefore that correlation does not equal causation?​


  4. ChatGPT said:​

    Yes — and I think your interpretation is basically right, with an important nuance.

    I looked specifically for replication of the 2023 Taiwanese finding rather than just studies showing that pregabalin can affect cognition.

    Has the Taiwanese result been replicated?​

    Not convincingly for pregabalin specifically, as far as I can find.

    The Taiwanese study was actually the first population-based cohort study specifically examining dementia risk from gabapentin/pregabalin, according to its authors. It combined the two drugs into one exposure group, rather than analyzing pregabalin alone. It found HR 1.45 (95% CI 1.36–1.55) for dementia.

    There is an important piece of evidence going in the other direction, though.

    A 2023 meta-analysis of observational studies of anti-seizure medications found no statistically significant association between pregabalin and dementia: pooled OR 0.84 (95% CI 0.64–1.11). Gabapentin was also not associated with increased dementia risk (OR 0.76, 95% CI 0.49–1.18).

    That isn't a perfect replication/non-replication test—the studies included in that meta-analysis aren't necessarily directly comparable to the Taiwanese cohort—but it certainly doesn't provide independent confirmation of a harmful pregabalin effect.

    There's also a newer observational study looking at gabapentin/pregabalin users in relation to kidney disease. Interestingly, in people without chronic kidney disease, gabapentin had essentially no difference in dementia risk compared with pregabalin (HR 1.09, 95% CI 0.89–1.34). That's not a test of pregabalin vs non-use, so it can't settle the question, but it illustrates how complicated these associations are.

    So, yes: correlation ≠ causation​

    More precisely, the Taiwanese study demonstrates:


    It does not demonstrate:


    That's an important distinction.

    The Taiwanese researchers themselves acknowledge that their study was retrospective and say that prospective studies are needed to understand whether there is a causal mechanism.

    There are several possible explanations for their result:
    • Confounding by indication: people taking pregabalin may have conditions that themselves increase dementia risk.
    • Age/health differences: people prescribed pregabalin may have more neurological disease, chronic pain, sleep problems, anxiety, etc.
    • Reverse causation: very early cognitive/neurological changes could contribute to symptoms that lead to pregabalin being prescribed.
    • Detection bias: people taking medication regularly may have more healthcare contact and therefore more opportunities for dementia to be diagnosed.
    • Drug effect: it is also possible that pregabalin genuinely contributes to cognitive impairment or dementia risk. The observational study cannot exclude this.
    • There's an especially interesting problem with the Taiwanese result
    The dose-response finding initially sounds quite compelling: dementia risk increased with cumulative exposure, with the highest exposure category having HR 2.44 compared with the lowest.

    Normally, a dose-response relationship makes a causal hypothesis more interesting.

    But there is something odd: the association was stronger in people under 50 than in older people. The reported HR was 3.16 in people under 50 versus 1.30 in people ≥70.

    That's not what I would expect if pregabalin were simply accelerating the usual neurodegenerative dementias of old age. It doesn't disprove causality, but it makes me considerably more cautious about interpreting the association as "pregabalin causes Alzheimer's/dementia."

    My reading of the evidence​

    If we rank the conclusions by confidence:

    High confidence:
    Pregabalin can cause CNS effects such as sedation, dizziness and cognitive impairment in some people. That's quite different from proving that it causes neurodegenerative dementia.

    Moderate confidence:
    There is an observational association between gabapentinoid use and subsequent dementia diagnoses in the Taiwanese dataset.

    Low confidence:
    Pregabalin itself increases the long-term biological risk of developing dementia.

    Currently unsupported:
    That pregabalin causes Alzheimer's disease or accelerates the underlying neurodegenerative process.

    And importantly, I would not regard the Taiwanese paper as established evidence that pregabalin causes dementia. The lack of clear independent replication, the fact that gabapentin and pregabalin were pooled, and the observational design all matter.

    If your underlying question is "Could pregabalin make an existing person's dementia or memory problems worse, and could that improve if pregabalin is reduced/stopped?", that's actually a much more clinically answerable question. The evidence there is different from the dementia-incidence question, and I can dig into that specifically.





    TopicPaper
    Year​
    Link
    Dementia risk — Taiwan cohortHuang Y-H, Pan M-H, Yang H-I. The association between Gabapentin or Pregabalin use and the risk of dementia: an analysis of the National Health Insurance Research Database in Taiwan.
    2023​
    Dementia risk — systematic review/meta-analysisGabapentinoid Use and Risk of Alzheimer's Disease-Related Dementias: A Systematic Review and Meta-analysis of Observational Studies.
    2026​
    Dementia risk — gabapentin in chronic painTsai SE, Yang SF, Wang YH, Yeh CB. Association between gabapentin use and risk of dementia in adults with chronic pain: A nested case-control study.
    2024​
    Behavioral symptoms — systematic reviewGabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report.
    2019​
    Behavioral symptoms — randomized trialA randomized, double-blind, placebo-controlled clinical trial to evaluate pregabalin efficacy in the treatment of behavioral and psychological symptoms of dementia in patients with Alzheimer's disease.
    2024​
    Gabapentinoids in older adults — reviewBenefits and risks of gabapentinoids in geriatric psychiatry.
    2025​







Im basing my suspicions of gabapentin and I don't trust Chat GPT nor majority of half these faulty studies these days with my body. Me personally I would exercise caution and just not take it and if you are gonna take it defiantly dont abuse. I'll add one more point do not put your faith in majority of these studies and you can call me conspiracy theorist all day long these guys have an agenda thats why I stay away from big pharma I dont trust much of anything these days. I seen them ravage my grandmother the last days with her dementia and it be day I hell id allow lyrica to be given to her they said Seroquel was safe and the other garbage they shoved down her throat and she was dead in a year that was straight up murder by doctors and the so called scientists. You watch enough of the damage these guys cause you learn the 99% percent of those studies are horseshit and completely fabricated.

When these guys been wrong on the cause of 99% of disease and thats not hyperbole. These guys have fumbled the ball that badly then the premise of the majority of thier studies falls apart. Me personally I would look at how it effects your memory when your on it and think is that something I want abuse and go with your gut feeling about how its gonna effect you in the future. It may not be right away then when you get 60 years of age maybe 50 depending on how bad you abused benzos and gabanoids you regret it thats all I'm saying. Dont put your health in the faith of these scientists they lost their way a while ago and only gotten worse since covid. I compare the times were in too the dark ages at this point were everything is being suppressed for the wealthy few so they stay wealthy.

Do I believe Lyrica and Gabapentin is the singular cause of Dementia absolutely not but things like that help tip you towards that disease quicker.
 
Last edited:
Im basing my suspicions of gabapentin
"suspicions" of a different drug, this is a pregablin thread.

and there doesn't seem to be any stronger evidence that what I've already linked above that gabapentin causes dementia either.

I have suspicions that you don't have any evidence and aren't an expert on dementia or pregablin/gabapentin.
I don't trust Chat GPT nor majority of half these faulty studies these days with my body.
you don't need to trust chat GPT I linked the papers, go and read them.

but conveniently you also don't trust the papers either.

so you want everyone to trust you because you have a hunch?

Me personally I would exercise caution and just not take it and if you are gonna take it defiantly dont abuse.
so basic HR as for any drug?

or are you saying "just say no".
I'll add one more point do not put your faith in majority of these studies
this is the best info we have.

and you can call me conspiracy theorist all day long these guys have an agenda thats why I stay away from big pharma I dont trust much of anything these days.
sometimes there's a lack of scientific evidence for something because it simply doesn't exist, not because there's a conspiracy
I seen them ravage my grandmother the last days with her dementia and it be day I hell id allow lyrica to be given to her they said Seroquel was safe and the other garbage they shoved down her throat and she was dead in a year that was straight up murder by doctors and the so called scientists. You watch enough of the damage these guys cause you learn the 99% percent of those studies are horseshit and completely fabricated.
I share your frustration at the effects of dementia and feel for you, my dad has it currently, it's an evil cruel disease.

a single subjective opinion though does not provide any scientific conclusion whatsoever.

based on the papers above I would feel happier letting my dad take pregablin/gabapentin to help him with his dementia than I would worry about the risk that it was going to give me dementia.

as you know, over time dementia gets worse, the Taiwan study seems very odd that there wasn't acceleration of symptoms for users over the age of 50, you would logically expect that to be the case if it's causing dementia in under 50s, and ironically this paper more likely reinforces that giving pregab/gabapentin to 50+ people with dementia is less risky for some potential benefit!

in truth these papers provide fuck all conclusions about pregab/gabapentin and dementia.

When these guys been wrong on the cause of 99% of disease and thats not hyperbole. These guys have fumbled the ball that badly then the premise of the majority of thier studies falls apart.
wtf?
Me personally I would look at how it effects your memory when your on it and think is that something I want abuse and go with your gut feeling about how its gonna effect you in the future.
fucking hell, you have no idea how drugs work do you?

I have no idea why you're on BL, but I would have thought you're a drug user, if you are for your own safety I sincerely hope you understand about the drugs that you do take.

do yourself a favor and go and read about Pharmacodynamics and Pharmacokinetics, educate yourself.
It may not be right away then when you get 60 years of age maybe 50 depending on how bad you abused benzos and gabanoids you regret it thats all I'm saying. Dont put your health in the faith of these scientists they lost their way a while ago and only gotten worse since covid.
fear mongering baseless crap - peer reviewed and corroborated published data or GTFO
I compare the times were in too the dark ages at this point were everything is being suppressed for the wealthy few so they stay wealthy.
Elon Musk doesn't give 2 shits who takes pregabalin, he's certainly not suppressing information about it causing dementia in the under 50s, he'll be long gone by the time those people get old
Do I believe Lyrica and Gabapentin is the singular cause of Dementia absolutely not but things like that help tip you towards that disease quicker.
provide proof that they "tip you towards" the disease or I'll go with what the research says than some random on the interwebs
 
"suspicions" of a different drug, this is a pregablin thread.

and there doesn't seem to be any stronger evidence that what I've already linked above that gabapentin causes dementia either.

I have suspicions that you don't have any evidence and aren't an expert on dementia or pregablin/gabapentin.

you don't need to trust chat GPT I linked the papers, go and read them.

but conveniently you also don't trust the papers either.

so you want everyone to trust you because you have a hunch?


so basic HR as for any drug?

or are you saying "just say no".

this is the best info we have.


sometimes there's a lack of scientific evidence for something because it simply doesn't exist, not because there's a conspiracy

I share your frustration at the effects of dementia and feel for you, my dad has it currently, it's an evil cruel disease.

a single subjective opinion though does not provide any scientific conclusion whatsoever.

based on the papers above I would feel happier letting my dad take pregablin/gabapentin to help him with his dementia than I would worry about the risk that it was going to give me dementia.

as you know, over time dementia gets worse, the Taiwan study seems very odd that there wasn't acceleration of symptoms for users over the age of 50, you would logically expect that to be the case if it's causing dementia in under 50s, and ironically this paper more likely reinforces that giving pregab/gabapentin to 50+ people with dementia is less risky for some potential benefit!

in truth these papers provide fuck all conclusions about pregab/gabapentin and dementia.


wtf?

fucking hell, you have no idea how drugs work do you?

I have no idea why you're on BL, but I would have thought you're a drug user, if you are for your own safety I sincerely hope you understand about the drugs that you do take.

do yourself a favor and go and read about Pharmacodynamics and Pharmacokinetics, educate yourself.

fear mongering baseless crap - peer reviewed and corroborated published data or GTFO

Elon Musk doesn't give 2 shits who takes pregabalin, he's certainly not suppressing information about it causing dementia in the under 50s, he'll be long gone by the time those people get old

provide proof that they "tip you towards" the disease or I'll go with what the research says than some random on the interwebs
Bro you can continue trust those guys and call it conspiracy bullshit all you want I seen enough of this were labs coats said was safe and they were dead wrong. All Im saying is read your body if you're taking substance that severely impairs your memory and abusing it at that I can almost guarantee you that its gonna help bring you too chronic disease quicker like dementia. Listen you can do what you want but you'll regret it when you're older and that sociopathic nurse is wiping your ass and physically abusing you. Now I see why this offends you so much your feeding your father poison I'd feel guilty too.

My thing with Pregabalin and Gabapentin is you dont get unless you consider Risperdal a high go at it.
 
Bro you can continue trust those guys and call it conspiracy bullshit all you want I seen enough of this were labs coats said was safe and they were dead wrong. All Im saying is read your body if you're taking substance that severely impairs your memory and abusing it at that I can almost guarantee you that its gonna help bring you too chronic disease quicker like dementia.
there is a difference between drug induced memory impact and permanent damage due to usage.

Current research has not shown that gabapentin or pregabalin typically cause permanent memory damage.

Listen you can do what you want but you'll regret it when you're older and that sociopathic nurse is wiping your ass and physically abusing you.
erm ok?
Now I see why this offends you so much your feeding your father poison I'd feel guilty too.
classy comeback
My thing with Pregabalin and Gabapentin is you dont get unless you consider Risperdal a high go at it.
that doesn't make any sense, I think you might be questioning if pregab or gabpentin gets you high?

I've never had risperdal but from what I've just read they are nothing alike.

I'm bored of this bollocks now, go and troll someone else
 
there is a difference between drug induced memory impact and permanent damage due to usage.

Current research has not shown that gabapentin or pregabalin typically cause permanent memory damage.


erm ok?

classy comeback

that doesn't make any sense, I think you might be questioning if pregab or gabpentin gets you high?

I've never had risperdal but from what I've just read they are nothing alike.

I'm bored of this bollocks now, go and troll someone else
Yeah I know just like those fairy tale studies showing the covid vaccine is safe as I watch everyone around me get cancer and chronic disease after getting it. But no no no continue too stick your heads in the clouds like the obvious isn't happening. Now apply that to gabapentin and pregabalin same shit if there doing it with everything else good chance there lying too you about that too. You know how many people I come across that now suffer memory problems and a whole slew other problems from that drug a lot. Then after you got all these people complaining about the drug. Fake studies coming out telling you how safe it is because there afraid of people not taking it anymore. Thats why so many people have lost trust in the system and for good reason.

I use to be just like you and realized oh shit Im actually getting sicker from the people who were suppose too help me. Boy did I did it shake me my world and it was hard fact to except just like every other part our government is corrupt so are those guys. It is a big club and you aren't allowed to know the truth unless you really dig.

No hate either brother you just trust the people that say there too help like a bunch of other people still determental too your wellbeing but just lost.
 
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