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Opinions of sertraline

ChemicallyEnhanced said:
It was a literal life-saver for me. I was suicidally depressed and having (sometimes more than one) panic attacks every day. It's not perfect and I wasn't miraculously 100% cured forever, but I'd say I was 85% better, it works most of the time and it completely turned my life around. Been on it for over 10 years now and going on it was one of the best decisions I've ever made. Could not recommend it any more strongly.
Hope it works for your son as well as it worked for me!
Just a warning: the first 3 days on an SSRI can make anxiety much worse. I actually snapped my in half and took 25mg for the first 6 days. That really helped the side-effects. Depending on how open you are with him, you could also let him know it is much more difficult to ejaculate for the first several weeks, but it goes away. Like, it takes a lot longer to cum and you have to have really fantasize more, but that's normal and it does go away.
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Bumping my own post :P since people are still asking about the drug.
 
It's the most benign ssri from what I've observed (20 years working in/around mental health-ish), having said that it is definitely nighmare-ish for some.

As a rough estimate I'd say it helps 30% of consumers, is neutral for 40%, negative effects for 25%, and a genuine nightmare for 5%.

For all other ssri's I'd go with helpful for 25%, neutral for 30%, negative for 30%, and a genuine nightmare for 15%
 
ageingpartyfiend said:
It's the most benign ssri from what I've observed (20 years working in/around mental health-ish), having said that it is definitely nighmare-ish for some.

As a rough estimate I'd say it helps 30% of consumers, is neutral for 40%, negative effects for 25%, and a genuine nightmare for 5%.

For all other ssri's I'd go with helpful for 25%, neutral for 30%, negative for 30%, and a genuine nightmare for 15%
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Do you think SSRIs are basically just a placebo?
 
I think that anything that blocks MDMA from working should be regarded with a weary eye. Serotonin as displayed by it's vast series of analogues seems to be more about regulating reality than just mood.

I have this thing whenever people mention SSRI's, where I ask them if they have cured their depression/anxiety. Nobody has ever told me they did. The closest I ever get is that people say they dull their emotions.

Humans are so weirdly detached from really deeply looking into and exploring the mind. It's literally taboo, to the point of incarceration. That says it all IMO.
 
Tranced said:
I have this thing whenever people mention SSRI's, where I ask them if they have cured their depression/anxiety. Nobody has ever told me they did. The closest I ever get is that people say they dull their emotions.
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which is a 'result' as far as the drug manufacturers and most doctors are concerned. Not depressed, but no happiness either. Just a zombie
 
Forever Changes said:
which is a 'result' as far as the drug manufacturers and most doctors are concerned. Not depressed, but no happiness either. Just a zombie
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Exactly. I was trying to find a really interesting and relevant point brought up on a Joe Rogan podcast but all I could find was this clip which pretty much sums up my opinion anyway. Very interesting thoughts from this guy. I'll listen to to the whole thing and post the thing that's lurking somewhere in the back of my brain, but this is worth a watch.

 
I’ve been taking Zoloft (sertraline) myself for quite a long time now, and honestly it’s worked very well for me in terms of anxiety and mood. The first couple of weeks can be a bit odd — things like dilated pupils, jitteriness, mild nausea or sleep changes aren’t unusual early on and often settle as the body adjusts. For many people, including me, the real benefits became clearer after a few weeks rather than immediately, so patience is important, especially at the start. It’s also really important to use only high-quality, legitimate Zoloft (sertraline) from a reliable pharmacy, because inconsistent or substandard products can lead to unstable blood levels, more side effects, or reduced effectiveness, which can seriously interfere with both adjustment and long-term results.

That's why I order effective Zoloft (Sertraline) from this reliable online pharmacy 👉 viteron.com/zoloft-sertraline, always excellent quality and fast delivery!

As for the grapefruit warning, that’s pretty standard now and more about being cautious with drug metabolism than something unique or especially dangerous with sertraline. I’ve always been advised to just avoid grapefruit products altogether while on SSRIs. My main advice would be to keep an eye on side effects during the first weeks, stay in close contact with the prescriber, and give it enough time before judging whether it’s helping — for a lot of us, sertraline turns out to be a very solid and reliable option.
 
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I've been on sertraline for about five months now. No complaints; little bit of insomnia here, little bit of temporary erectile dysfunction. All gone.

I'm on two other powerful medications. Sertraline made me feel like a zombie for a few weeks, then it kicked in. It's not bad.

I think part of the resistance of the likes of @Forever Changes (no, it's not placebo) is that they want something enjoyable. Well I'll tell you what's enjoyable; that's relief from deep depression.
 
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Perkins : Reborn said:
I've been on sertraline for about five months now. No complaints; little bit of insomnia here, little bit of temporary erectile dysfunction. All gone.

I'm on two other powerful medications. Sertraline made me feel like a zombie for a few weeks, then it kicked in. It's not bad.

I think part of the resistance of the likes of @Forever Changes (no, it's not placebo) is that they want something enjoyable. Well I'll tell you what's enjoyable; that's relief from deep depression.
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Is that what it's providing then? Noticeable relief?

edit - it does appear to be the 'lightest' ssri in terms of bad side effects
 
Yeah. I really didn't want to try it, but a psychiatrist encouraged me to give it a go, and it really did something.

Problem now is a charming young woman who's been keeping a diary on how 'offensive' I am. Despite working with 95% women who absolutely love me. So one step forward, two steps backward. Down in a Babylon.
 
Perkins : Reborn said:
Yeah. I really didn't want to try it, but a psychiatrist encouraged me to give it a go, and it really did something.

Problem now is a charming young woman who's been keeping a diary on how 'offensive' I am. Despite working with 95% women who absolutely love me. So one step forward, two steps backward. Down in a Babylon.
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Tune
 
I couldnt tolerate any SSRIs and I gave them a good go thinking that all those late nights in the 90s might be paying me back. It was mainly nuasue and confufion, proxac made me proectile vomit and Sertraline may well have caused minor internal bleeding. Tried all kinds, tricyslics did nothing at all in the end I went on Venlafaxine but the WD is a bitch
 
Well I'm on an experimental doubled dose, and the first two nights have been interesting.

I woke up feeling like I was on MDMA, and had my own club night with a duvet, some vodka and a bit of weed, plus tunes. I almost felt like going out, but the quetiapine meant I'd end up in hospital or the cells.

Those effects will wear off soon enough. Other effects (mania) I'll have to watch.
 
Mate if nothing ssri wise works you could go picking shrooms and microdose. Empty the ssris out the capsules he's stopped taking if you dont want him knowing, but I'd probably be honest with the laddie.
Pm me if you want anything more mate.
My good friend friend was on sertraline cos of stress and anxiety and he said it helped a lot. Sorry lotta pages so don't know whats been said already he said it helped.
My late fiancée was on it too but only started a few weeks before she died. She said it made her anxiety worse and got side effects.
 
Perkins : Reborn said:
Well I'm on an experimental doubled dose, and the first two nights have been interesting.

I woke up feeling like I was on MDMA, and had my own club night with a duvet, some vodka and a bit of weed, plus tunes. I almost felt like going out, but the quetiapine meant I'd end up in hospital or the cells.

Those effects will wear off soon enough. Other effects (mania) I'll have to watch.
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Aye! A long time ago I tried an snri called venlafaxine or summit. Felt like I was coming up on an e but in a horrible dirty way. Got the horn for some reason so stuck on some porn. As bad as pregabalin for the inability to come.
Fuck if I couldn't come or wank at 15 id probably have carved a fucking palace!
 
axe battler said:
Mate if nothing ssri wise works you could go picking shrooms and microdose. Empty the ssris out the capsules he's stopped taking if you dont want him knowing, but I'd probably be honest with the laddie.
Pm me if you want anything more mate.
My good friend friend was on sertraline cos of stress and anxiety and he said it helped a lot. Sorry lotta pages so don't know whats been said already he said it helped.
My late fiancée was on it too but only started a few weeks before she died. She said it made her anxiety worse and got side effects.
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Strangely enough, a dose of mushrooms was the last revelatory experience I had. The only reason I haven't followed up is the real life shit I've had on my plate over the past eighteen months.

It's hard to take a decent dose and then go back into an office with people who behave like chimpanzees without ever knowing it.
 
AI reckons that SSRIs in general have substantial benefits for 50%-70% of people who need help with their depression or anxiety.

I think that figure is far too high, as although I'm aware that more people tend to post online about negative experiences rather than positive ones, it still seems to me that vast numbers of people find this class of meds offer them very little help, especially for anxiety. Which they are supposed to be also helpful for.

Mirtazapine does help me sleep, even years after starting it, but neither it nor the 2 other SSRIs I tried previously; paroxetine, and sertaline, made the slightest difference to my anxiety. The Drs told me that each one would help me with my anxiety. They did absolutely fuck all for me in that regard. I get the impression that the whole class of drugs are broadly similar. If one doesnt work, there's not going to be a huge difference in another. Kind of like how all benzos are broadly similar, with only relatively minor differnces between different ones, along the hypnotic and anxiolytic scales.

.I don't see any point in going through the horrors of withdrawring from a long term mirtazapine script, just to try one more SSRI that most likely wont do anything for my anxiety either. I have heard it said by many that venlefaxine helped their anxiety. If I knew that earlier, before I'd been on Mirtazapine for so long, I'd have tried it. But now that I have, I don't think it's worth it. I very highly doubt it would help in the least bit, and all the horrors of withdrawing from a long term mirtazapine script would be totally in vain.

With hindisght I now believe that my low mood was more a reaction to my life situation, with the difficulties being caused by my undiagnosed Autism and ADHD, rather than actual clinical depression. I faked a couple of the ridiculously brief 5 question "depression test" I had to answer with the GP in order to get started on the scripts. It was obvious how I needed to answer, in order to 'pass' the test. Within less then 5 minutes I was started on a long SSRI journey, with no idea of how difficult coming off these meds is. I either wish I'd never started them at all, or at least tried venlefaxine much sooner, and then if that wasnt working after a few months, I'd have just stopped using them completely.

Isn't hindsight wonderful. If I'd have known what I know now all those years ago, I would have done things very differently. I was not advised well by the GPs at all. No mention was made of the difficulties of the 'withdrawl syndromes', said by some to be even worse than the withdrawals following long term benzodiazepine use. I'm not entirely convinced about that. But at some point I may try coming off mirtazapine. I'll probably have at least a couple of months of severe insomnia to look forward to, and God knows what other symptoms besides. No mention was made of the benefits of trying something like Venlefaxine for anxiety, when the other 3 anti-depressants had failed. Either the GPs did not know about any of this, or they neglected to inform me.

There was no internet back then, with ready access to huge numbers of individual experiences, and any other information that might have been life changingly helpful.
 
Bleaney said:
AI reckons that SSRIs in general have substantial benefits for 50%-70% of people who need help with their depression or anxiety.

I think that figure is far too high, as although I'm aware that more people tend to post online about negative experiences rather than positive ones, it still seems to me that vast numbers of people find this class of meds offer them very little help, especially for anxiety. Which they are supposed to be also helpful for.

Mirtazapine does help me sleep, even years after starting it, but neither it nor the 2 other SSRIs I tried previously; paroxetine, and sertaline, made the slightest difference to my anxiety. The Drs told me that each one would help me with my anxiety. They did absolutely fuck all for me in that regard. I get the impression that the whole class of drugs are broadly similar. If one doesnt work, there's not going to be a huge difference in another. Kind of like how all benzos are broadly similar, with only relatively minor differnces between different ones, along the hypnotic and anxiolytic scales.

.I don't see any point in going through the horrors of withdrawring from a long term mirtazapine script, just to try one more SSRI that most likely wont do anything for my anxiety either. I have heard it said by many that venlefaxine helped their anxiety. If I knew that earlier, before I'd been on Mirtazapine for so long, I'd have tried it. But now that I have, I don't think it's worth it. I very highly doubt it would help in the least bit, and all the horrors of withdrawing from a long term mirtazapine script would be totally in vain.

With hindisght I now believe that my low mood was more a reaction to my life situation, with the difficulties being caused by my undiagnosed Autism and ADHD, rather than actual clinical depression. I faked a couple of the ridiculously brief 5 question "depression test" I had to answer with the GP in order to get started on the scripts. It was obvious how I needed to answer, in order to 'pass' the test. Within less then 5 minutes I was started on a long SSRI journey, with no idea of how difficult coming off these meds is. I either wish I'd never started them at all, or at least tried venlefaxine much sooner, and then if that wasnt working after a few months, I'd have just stopped using them completely.

Isn't hindsight wonderful. If I'd have known what I know now all those years ago, I would have done things very differently. I was not advised well by the GPs at all. No mention was made of the difficulties of the 'withdrawl syndromes', said by some to be even worse than the withdrawals following long term benzodiazepine use. I'm not entirely convinced about that. But at some point I may try coming off mirtazapine. I'll probably have at least a couple of months of severe insomnia to look forward to, and God knows what other symptoms besides. No mention was made of the benefits of trying something like Venlefaxine for anxiety, when the other 3 anti-depressants had failed. Either the GPs did not know about any of this, or they neglected to inform me.

There was no internet back then, with ready access to huge numbers of individual experiences, and any other information that might have been life changingly helpful.
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Having been on setraline and now venlafaxin for a while i do want to say its felt like an actual "depression medication" and not the wishy washyness of base ssris, setraline at 200mgs felt no different than 100mgs. Venla is very different there, i can certainly say it helped me like no med so far has in staying alive and functioning. You speak off the withdrawls associated with mirta and i just wanted to add that at a dose that actually affects the norephedrine, venla could likely be worse there. I only missed a 225mg dose once so far and i dont intend to repeat it. Tapering is basically requierd, if you ask your gp for it you might be able to bridge it with the venla though and side effects are more common with it. I'd reccomend it if you know about the high side effect chances and the unbelievable physical depndance.
 
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